Chlorine in PDB 7w4o: The Structure of Katp H175K Mutant in Pre-Open State

The structure of The Structure of Katp H175K Mutant in Pre-Open State also contains other interesting chemical elements:

Magnesium

(Mg)

8 atoms

The binding sites of Chlorine atom in the The Structure of Katp H175K Mutant in Pre-Open State (pdb code 7w4o). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the The Structure of Katp H175K Mutant in Pre-Open State, PDB code: 7w4o:
Jump to Chlorine binding site number: 1; 2; 3; 4;

Chlorine binding site 1 out of 4 in the The Structure of Katp H175K Mutant in Pre-Open State


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of The Structure of Katp H175K Mutant in Pre-Open State within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl1604 b:107.2 occ:1.00 CL1 B:E2H1604 0.0 107.2 1.0 C17 B:E2H1604 1.8 85.5 1.0 C16 B:E2H1604 2.8 81.8 1.0 S03 B:E2H1604 3.0 88.4 1.0 O B:ILE552 3.4 76.6 1.0 SG B:CYS1072 3.5 93.6 1.0 CA B:ILE552 3.5 71.0 1.0 CG2 B:ILE552 3.6 77.8 1.0 CG1 B:VAL555 3.6 75.2 1.0 CB B:VAL555 3.8 70.3 1.0 C B:ILE552 3.9 73.4 1.0 CB B:ILE552 3.9 72.1 1.0 CG1 B:ILE552 4.1 70.0 1.0 CG2 B:ILE1030 4.2 71.8 1.0 C14 B:E2H1604 4.2 78.0 1.0 C15 B:E2H1604 4.3 79.8 1.0 N B:LEU556 4.5 73.6 1.0 CD1 B:ILE1030 4.5 76.0 1.0 CB B:CYS1072 4.6 82.5 1.0 O B:PRO551 4.6 80.0 1.0 CZ B:PHE1068 4.7 78.0 1.0 N B:ILE552 4.7 72.0 1.0 CG2 B:VAL555 4.8 75.7 1.0 CA B:VAL555 4.9 66.9 1.0 C B:VAL555 4.9 70.4 1.0

Chlorine binding site 2 out of 4 in the The Structure of Katp H175K Mutant in Pre-Open State


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of The Structure of Katp H175K Mutant in Pre-Open State within 5.0Å range: probe atom residue distance (Å) B Occ D:Cl1604 b:107.2 occ:1.00 CL1 D:E2H1604 0.0 107.2 1.0 C17 D:E2H1604 1.8 85.5 1.0 C16 D:E2H1604 2.8 81.8 1.0 S03 D:E2H1604 3.0 88.4 1.0 O D:ILE552 3.4 76.6 1.0 SG D:CYS1072 3.5 93.6 1.0 CA D:ILE552 3.5 71.0 1.0 CG2 D:ILE552 3.6 77.8 1.0 CG1 D:VAL555 3.6 75.2 1.0 CB D:VAL555 3.8 70.3 1.0 C D:ILE552 3.9 73.4 1.0 CB D:ILE552 3.9 72.1 1.0 CG1 D:ILE552 4.1 70.0 1.0 CG2 D:ILE1030 4.2 71.8 1.0 C14 D:E2H1604 4.2 78.0 1.0 C15 D:E2H1604 4.3 79.8 1.0 N D:LEU556 4.5 73.6 1.0 CD1 D:ILE1030 4.5 76.0 1.0 CB D:CYS1072 4.6 82.5 1.0 O D:PRO551 4.6 80.0 1.0 CZ D:PHE1068 4.7 78.0 1.0 N D:ILE552 4.7 72.0 1.0 CG2 D:VAL555 4.8 75.7 1.0 CA D:VAL555 4.9 66.9 1.0 C D:VAL555 4.9 70.4 1.0

Chlorine binding site 3 out of 4 in the The Structure of Katp H175K Mutant in Pre-Open State


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of The Structure of Katp H175K Mutant in Pre-Open State within 5.0Å range: probe atom residue distance (Å) B Occ F:Cl1604 b:107.2 occ:1.00 CL1 F:E2H1604 0.0 107.2 1.0 C17 F:E2H1604 1.8 85.5 1.0 C16 F:E2H1604 2.8 81.8 1.0 S03 F:E2H1604 3.0 88.4 1.0 O F:ILE552 3.4 76.6 1.0 SG F:CYS1072 3.5 93.6 1.0 CA F:ILE552 3.5 71.0 1.0 CG2 F:ILE552 3.6 77.8 1.0 CG1 F:VAL555 3.6 75.2 1.0 CB F:VAL555 3.8 70.3 1.0 C F:ILE552 3.9 73.4 1.0 CB F:ILE552 3.9 72.1 1.0 CG1 F:ILE552 4.1 70.0 1.0 CG2 F:ILE1030 4.2 71.8 1.0 C14 F:E2H1604 4.2 78.0 1.0 C15 F:E2H1604 4.3 79.8 1.0 N F:LEU556 4.5 73.6 1.0 CD1 F:ILE1030 4.5 76.0 1.0 CB F:CYS1072 4.6 82.5 1.0 O F:PRO551 4.6 80.0 1.0 CZ F:PHE1068 4.7 78.0 1.0 N F:ILE552 4.7 72.0 1.0 CG2 F:VAL555 4.8 75.7 1.0 CA F:VAL555 4.9 66.9 1.0 C F:VAL555 4.9 70.4 1.0

Chlorine binding site 4 out of 4 in the The Structure of Katp H175K Mutant in Pre-Open State


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of The Structure of Katp H175K Mutant in Pre-Open State within 5.0Å range: probe atom residue distance (Å) B Occ H:Cl1604 b:107.2 occ:1.00 CL1 H:E2H1604 0.0 107.2 1.0 C17 H:E2H1604 1.8 85.5 1.0 C16 H:E2H1604 2.8 81.8 1.0 S03 H:E2H1604 3.0 88.4 1.0 O H:ILE552 3.4 76.6 1.0 SG H:CYS1072 3.5 93.6 1.0 CA H:ILE552 3.5 71.0 1.0 CG2 H:ILE552 3.6 77.8 1.0 CG1 H:VAL555 3.6 75.2 1.0 CB H:VAL555 3.8 70.3 1.0 C H:ILE552 3.9 73.4 1.0 CB H:ILE552 3.9 72.1 1.0 CG1 H:ILE552 4.1 70.0 1.0 CG2 H:ILE1030 4.2 71.8 1.0 C14 H:E2H1604 4.2 78.0 1.0 C15 H:E2H1604 4.3 79.8 1.0 N H:LEU556 4.5 73.6 1.0 CD1 H:ILE1030 4.5 76.0 1.0 CB H:CYS1072 4.6 82.5 1.0 O H:PRO551 4.6 80.0 1.0 CZ H:PHE1068 4.7 78.0 1.0 N H:ILE552 4.7 72.0 1.0 CG2 H:VAL555 4.8 75.7 1.0 CA H:VAL555 4.9 66.9 1.0 C H:VAL555 4.9 70.4 1.0

M.Wang, J.X.Wu, D.Ding, L.Chen. Structural Insights Into the Mechanism of Pancreatic K Atp Channel Regulation By Nucleotides. Nat Commun V. 13 2770 2022.
ISSN: ESSN 2041-1723
PubMed: 35589716
DOI: 10.1038/S41467-022-30430-4