Chlorine in PDB 7w4p: The Structure of Katp H175K Mutant in Closed State

The structure of The Structure of Katp H175K Mutant in Closed State also contains other interesting chemical elements:

Magnesium

(Mg)

8 atoms

The binding sites of Chlorine atom in the The Structure of Katp H175K Mutant in Closed State (pdb code 7w4p). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the The Structure of Katp H175K Mutant in Closed State, PDB code: 7w4p:
Jump to Chlorine binding site number: 1; 2; 3; 4;

Chlorine binding site 1 out of 4 in the The Structure of Katp H175K Mutant in Closed State


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of The Structure of Katp H175K Mutant in Closed State within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl1604 b:84.5 occ:1.00 CL1 B:E2H1604 0.0 84.5 1.0 C17 B:E2H1604 1.8 79.1 1.0 C16 B:E2H1604 2.9 78.8 1.0 S03 B:E2H1604 3.0 89.8 1.0 SG B:CYS1072 3.4 79.0 1.0 CG1 B:VAL555 3.5 62.1 1.0 CG2 B:ILE1030 3.7 49.9 1.0 O B:ILE552 3.8 67.7 1.0 CG2 B:ILE552 3.9 53.5 1.0 CB B:VAL555 4.0 58.0 1.0 CA B:ILE552 4.1 54.6 1.0 CZ B:PHE1068 4.2 56.5 1.0 C14 B:E2H1604 4.2 79.0 1.0 C15 B:E2H1604 4.2 78.8 1.0 CD1 B:ILE1030 4.3 56.9 1.0 C B:ILE552 4.4 52.5 1.0 CB B:ILE552 4.4 52.6 1.0 N B:LEU556 4.6 47.5 1.0 CG1 B:ILE552 4.7 57.0 1.0 CB B:CYS1072 4.7 50.7 1.0 CE2 B:PHE1068 4.7 51.7 1.0 CE1 B:PHE1068 4.8 53.4 1.0 CB B:ILE1030 4.9 45.7 1.0 C B:VAL555 5.0 47.6 1.0

Chlorine binding site 2 out of 4 in the The Structure of Katp H175K Mutant in Closed State


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of The Structure of Katp H175K Mutant in Closed State within 5.0Å range: probe atom residue distance (Å) B Occ D:Cl1604 b:84.5 occ:1.00 CL1 D:E2H1604 0.0 84.5 1.0 C17 D:E2H1604 1.8 79.1 1.0 C16 D:E2H1604 2.9 78.8 1.0 S03 D:E2H1604 3.0 89.8 1.0 SG D:CYS1072 3.4 79.0 1.0 CG1 D:VAL555 3.5 62.1 1.0 CG2 D:ILE1030 3.7 49.9 1.0 O D:ILE552 3.8 67.7 1.0 CG2 D:ILE552 3.9 53.5 1.0 CB D:VAL555 4.0 58.0 1.0 CA D:ILE552 4.1 54.6 1.0 CZ D:PHE1068 4.2 56.5 1.0 C14 D:E2H1604 4.2 79.0 1.0 C15 D:E2H1604 4.2 78.8 1.0 CD1 D:ILE1030 4.3 56.9 1.0 C D:ILE552 4.4 52.5 1.0 CB D:ILE552 4.4 52.6 1.0 N D:LEU556 4.6 47.5 1.0 CG1 D:ILE552 4.7 57.0 1.0 CB D:CYS1072 4.7 50.7 1.0 CE2 D:PHE1068 4.7 51.7 1.0 CE1 D:PHE1068 4.8 53.4 1.0 CB D:ILE1030 4.9 45.7 1.0 C D:VAL555 5.0 47.6 1.0

Chlorine binding site 3 out of 4 in the The Structure of Katp H175K Mutant in Closed State


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of The Structure of Katp H175K Mutant in Closed State within 5.0Å range: probe atom residue distance (Å) B Occ F:Cl1604 b:84.5 occ:1.00 CL1 F:E2H1604 0.0 84.5 1.0 C17 F:E2H1604 1.8 79.1 1.0 C16 F:E2H1604 2.9 78.8 1.0 S03 F:E2H1604 3.0 89.8 1.0 SG F:CYS1072 3.4 79.0 1.0 CG1 F:VAL555 3.5 62.1 1.0 CG2 F:ILE1030 3.7 49.9 1.0 O F:ILE552 3.8 67.7 1.0 CG2 F:ILE552 3.9 53.5 1.0 CB F:VAL555 4.0 58.0 1.0 CA F:ILE552 4.1 54.6 1.0 CZ F:PHE1068 4.2 56.5 1.0 C14 F:E2H1604 4.2 79.0 1.0 C15 F:E2H1604 4.2 78.8 1.0 CD1 F:ILE1030 4.3 56.9 1.0 C F:ILE552 4.4 52.5 1.0 CB F:ILE552 4.4 52.6 1.0 N F:LEU556 4.6 47.5 1.0 CG1 F:ILE552 4.7 57.0 1.0 CB F:CYS1072 4.7 50.7 1.0 CE2 F:PHE1068 4.7 51.7 1.0 CE1 F:PHE1068 4.8 53.4 1.0 CB F:ILE1030 4.9 45.7 1.0 C F:VAL555 5.0 47.6 1.0

Chlorine binding site 4 out of 4 in the The Structure of Katp H175K Mutant in Closed State


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of The Structure of Katp H175K Mutant in Closed State within 5.0Å range: probe atom residue distance (Å) B Occ H:Cl1604 b:84.5 occ:1.00 CL1 H:E2H1604 0.0 84.5 1.0 C17 H:E2H1604 1.8 79.1 1.0 C16 H:E2H1604 2.9 78.8 1.0 S03 H:E2H1604 3.0 89.8 1.0 SG H:CYS1072 3.4 79.0 1.0 CG1 H:VAL555 3.5 62.1 1.0 CG2 H:ILE1030 3.7 49.9 1.0 O H:ILE552 3.8 67.7 1.0 CG2 H:ILE552 3.9 53.5 1.0 CB H:VAL555 4.0 58.0 1.0 CA H:ILE552 4.1 54.6 1.0 CZ H:PHE1068 4.2 56.5 1.0 C14 H:E2H1604 4.2 79.0 1.0 C15 H:E2H1604 4.2 78.8 1.0 CD1 H:ILE1030 4.3 56.9 1.0 C H:ILE552 4.4 52.5 1.0 CB H:ILE552 4.4 52.6 1.0 N H:LEU556 4.6 47.5 1.0 CG1 H:ILE552 4.7 57.0 1.0 CB H:CYS1072 4.7 50.7 1.0 CE2 H:PHE1068 4.7 51.7 1.0 CE1 H:PHE1068 4.8 53.4 1.0 CB H:ILE1030 4.9 45.7 1.0 C H:VAL555 5.0 47.6 1.0

M.Wang, J.X.Wu, D.Ding, L.Chen. Structural Insights Into the Mechanism of Pancreatic K Atp Channel Regulation By Nucleotides. Nat Commun V. 13 2770 2022.
ISSN: ESSN 2041-1723
PubMed: 35589716
DOI: 10.1038/S41467-022-30430-4