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Chlorine in PDB 7wcx: Crystal Structure of FGFR4(V550M) Kinase Domain with 7VEnzymatic activity of Crystal Structure of FGFR4(V550M) Kinase Domain with 7V
All present enzymatic activity of Crystal Structure of FGFR4(V550M) Kinase Domain with 7V:
2.7.10.1; Protein crystallography data
The structure of Crystal Structure of FGFR4(V550M) Kinase Domain with 7V, PDB code: 7wcx
was solved by
X.J.Chen,
Q.M.Lin,
S.Y.Dai,
Y.H.Chen,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 7wcx:
The structure of Crystal Structure of FGFR4(V550M) Kinase Domain with 7V also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of FGFR4(V550M) Kinase Domain with 7V
(pdb code 7wcx). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of FGFR4(V550M) Kinase Domain with 7V, PDB code: 7wcx: Jump to Chlorine binding site number: 1; 2; Chlorine binding site 1 out of 2 in 7wcxGo back to Chlorine Binding Sites List in 7wcx
Chlorine binding site 1 out
of 2 in the Crystal Structure of FGFR4(V550M) Kinase Domain with 7V
Mono view Stereo pair view
Chlorine binding site 2 out of 2 in 7wcxGo back to Chlorine Binding Sites List in 7wcx
Chlorine binding site 2 out
of 2 in the Crystal Structure of FGFR4(V550M) Kinase Domain with 7V
Mono view Stereo pair view
Reference:
M.Shao,
X.Chen,
F.Yang,
X.Song,
Y.Zhou,
Q.Lin,
Y.Fu,
R.Ortega,
X.Lin,
Z.Tu,
A.V.Patterson,
J.B.Smaill,
Y.Chen,
X.Lu.
Design, Synthesis, and Biological Evaluation of Aminoindazole Derivatives As Highly Selective Covalent Inhibitors of Wild-Type and Gatekeeper Mutant FGFR4. J.Med.Chem. V. 65 5113 2022.
Page generated: Tue Apr 4 22:13:11 2023
ISSN: ISSN 0022-2623 PubMed: 35271262 DOI: 10.1021/ACS.JMEDCHEM.2C00096 |
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