Chlorine in PDB 7xbi: The Crystal Structure of Human Trka Kinase Bound to the Inhibitor

Enzymatic activity of The Crystal Structure of Human Trka Kinase Bound to the Inhibitor

All present enzymatic activity of The Crystal Structure of Human Trka Kinase Bound to the Inhibitor:
2.7.10.1;

Protein crystallography data

The structure of The Crystal Structure of Human Trka Kinase Bound to the Inhibitor, PDB code: 7xbi was solved by C.Y.Wu, G.Wang, L.Ouyang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 29.16 / 2.16
Space group P 31 1 2
Cell size a, b, c (Å), α, β, γ (°) 52.01, 52.01, 229.51, 90, 90, 120
R / Rfree (%) 18.8 / 24.6

Other elements in 7xbi:

The structure of The Crystal Structure of Human Trka Kinase Bound to the Inhibitor also contains other interesting chemical elements:

Fluorine (F) 7 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the The Crystal Structure of Human Trka Kinase Bound to the Inhibitor (pdb code 7xbi). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the The Crystal Structure of Human Trka Kinase Bound to the Inhibitor, PDB code: 7xbi:

Chlorine binding site 1 out of 1 in 7xbi

Go back to Chlorine Binding Sites List in 7xbi
Chlorine binding site 1 out of 1 in the The Crystal Structure of Human Trka Kinase Bound to the Inhibitor


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of The Crystal Structure of Human Trka Kinase Bound to the Inhibitor within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl802

b:49.7
occ:1.00
 H A:SER672 2.4 97.8 1.0
HH21 A:ARG673 2.5 57.0 1.0
HE A:ARG673 2.5 59.1 1.0
H A:ARG673 2.6 78.2 1.0
HA A:MET671 2.7 78.7 1.0
N A:SER672 3.2 81.5 1.0
HB2 A:ARG673 3.2 81.9 1.0
NH2 A:ARG673 3.3 47.5 1.0
HB2 A:TYR676 3.3 39.3 1.0
NE A:ARG673 3.4 49.3 1.0
N A:ARG673 3.4 65.2 1.0
HE2 A:TYR680 3.4 31.6 1.0
CA A:MET671 3.5 65.6 1.0
H A:MET671 3.6 83.9 1.0
HD2 A:TYR676 3.7 47.3 1.0
HD2 A:ARG654 3.7 29.8 1.0
HB2 A:PHE669 3.7 58.0 1.0
CZ A:ARG673 3.8 41.5 1.0
C A:MET671 3.8 73.2 1.0
HB3 A:PHE669 3.9 58.0 1.0
N A:MET671 3.9 70.0 1.0
HH22 A:ARG673 4.0 57.0 1.0
CB A:ARG673 4.0 68.2 1.0
OH A:TYR680 4.0 31.4 1.0
HG3 A:ARG673 4.1 70.0 1.0
CE2 A:TYR680 4.2 26.4 1.0
CA A:SER672 4.2 74.2 1.0
CB A:TYR676 4.2 32.8 1.0
CA A:ARG673 4.2 74.4 1.0
C A:SER672 4.3 74.9 1.0
CB A:PHE669 4.3 48.4 1.0
O A:ARG673 4.3 64.4 1.0
HB3 A:TYR676 4.4 39.3 1.0
CG A:ARG673 4.4 58.4 1.0
CD2 A:TYR676 4.5 39.4 1.0
CZ A:TYR680 4.5 31.0 1.0
CD A:ARG673 4.5 50.7 1.0
HE A:ARG654 4.5 34.6 1.0
OG A:SER672 4.6 67.3 1.0
HH A:TYR680 4.7 37.7 1.0
CD A:ARG654 4.7 24.9 1.0
HB3 A:ARG673 4.8 81.9 1.0
C A:ARG673 4.8 61.9 1.0
CB A:MET671 4.8 52.4 1.0
CG A:TYR676 4.8 33.3 1.0
HG3 A:MET671 4.8 73.6 1.0
HB3 A:MET671 4.9 62.9 1.0
HG3 A:ARG654 4.9 27.4 1.0
CB A:SER672 4.9 70.9 1.0
HA A:SER672 4.9 89.0 1.0
O A:MET671 5.0 59.1 1.0

Reference:

C.Y.Wu, G.Wang, L.Ouyang. The Crystal Structure of Human Trka Kinase Bound to the Inhibitor To Be Published.
Page generated: Tue Jul 30 05:45:43 2024

Last articles

Zn in 9MJ5
Zn in 9HNW
Zn in 9G0L
Zn in 9FNE
Zn in 9DZN
Zn in 9E0I
Zn in 9D32
Zn in 9DAK
Zn in 8ZXC
Zn in 8ZUF
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy