Chlorine in PDB 7xbi: The Crystal Structure of Human Trka Kinase Bound to the Inhibitor

Enzymatic activity of The Crystal Structure of Human Trka Kinase Bound to the Inhibitor

All present enzymatic activity of The Crystal Structure of Human Trka Kinase Bound to the Inhibitor:
2.7.10.1;

Protein crystallography data

The structure of The Crystal Structure of Human Trka Kinase Bound to the Inhibitor, PDB code: 7xbi was solved by C.Y.Wu, G.Wang, L.Ouyang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 29.16 / 2.16
Space group P 31 1 2
Cell size a, b, c (Å), α, β, γ (°) 52.01, 52.01, 229.51, 90, 90, 120
R / Rfree (%) 18.8 / 24.6

Other elements in 7xbi:

The structure of The Crystal Structure of Human Trka Kinase Bound to the Inhibitor also contains other interesting chemical elements:

Fluorine (F) 7 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the The Crystal Structure of Human Trka Kinase Bound to the Inhibitor (pdb code 7xbi). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the The Crystal Structure of Human Trka Kinase Bound to the Inhibitor, PDB code: 7xbi:

Chlorine binding site 1 out of 1 in 7xbi

Go back to Chlorine Binding Sites List in 7xbi
Chlorine binding site 1 out of 1 in the The Crystal Structure of Human Trka Kinase Bound to the Inhibitor


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of The Crystal Structure of Human Trka Kinase Bound to the Inhibitor within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl802

b:49.7
occ:1.00
 H A:SER672 2.4 97.8 1.0
HH21 A:ARG673 2.5 57.0 1.0
HE A:ARG673 2.5 59.1 1.0
H A:ARG673 2.6 78.2 1.0
HA A:MET671 2.7 78.7 1.0
N A:SER672 3.2 81.5 1.0
HB2 A:ARG673 3.2 81.9 1.0
NH2 A:ARG673 3.3 47.5 1.0
HB2 A:TYR676 3.3 39.3 1.0
NE A:ARG673 3.4 49.3 1.0
N A:ARG673 3.4 65.2 1.0
HE2 A:TYR680 3.4 31.6 1.0
CA A:MET671 3.5 65.6 1.0
H A:MET671 3.6 83.9 1.0
HD2 A:TYR676 3.7 47.3 1.0
HD2 A:ARG654 3.7 29.8 1.0
HB2 A:PHE669 3.7 58.0 1.0
CZ A:ARG673 3.8 41.5 1.0
C A:MET671 3.8 73.2 1.0
HB3 A:PHE669 3.9 58.0 1.0
N A:MET671 3.9 70.0 1.0
HH22 A:ARG673 4.0 57.0 1.0
CB A:ARG673 4.0 68.2 1.0
OH A:TYR680 4.0 31.4 1.0
HG3 A:ARG673 4.1 70.0 1.0
CE2 A:TYR680 4.2 26.4 1.0
CA A:SER672 4.2 74.2 1.0
CB A:TYR676 4.2 32.8 1.0
CA A:ARG673 4.2 74.4 1.0
C A:SER672 4.3 74.9 1.0
CB A:PHE669 4.3 48.4 1.0
O A:ARG673 4.3 64.4 1.0
HB3 A:TYR676 4.4 39.3 1.0
CG A:ARG673 4.4 58.4 1.0
CD2 A:TYR676 4.5 39.4 1.0
CZ A:TYR680 4.5 31.0 1.0
CD A:ARG673 4.5 50.7 1.0
HE A:ARG654 4.5 34.6 1.0
OG A:SER672 4.6 67.3 1.0
HH A:TYR680 4.7 37.7 1.0
CD A:ARG654 4.7 24.9 1.0
HB3 A:ARG673 4.8 81.9 1.0
C A:ARG673 4.8 61.9 1.0
CB A:MET671 4.8 52.4 1.0
CG A:TYR676 4.8 33.3 1.0
HG3 A:MET671 4.8 73.6 1.0
HB3 A:MET671 4.9 62.9 1.0
HG3 A:ARG654 4.9 27.4 1.0
CB A:SER672 4.9 70.9 1.0
HA A:SER672 4.9 89.0 1.0
O A:MET671 5.0 59.1 1.0

Reference:

C.Y.Wu, G.Wang, L.Ouyang. The Crystal Structure of Human Trka Kinase Bound to the Inhibitor To Be Published.
Page generated: Tue Jul 30 05:45:43 2024

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