Chlorine in PDB 7xi2: Crystal Structure of Escherichia Coli Adenine Phosphoribosyltransferase (Aprt) in Complex with Phosphate

All present enzymatic activity of Crystal Structure of Escherichia Coli Adenine Phosphoribosyltransferase (Aprt) in Complex with Phosphate:
2.4.2.7;

The structure of Crystal Structure of Escherichia Coli Adenine Phosphoribosyltransferase (Aprt) in Complex with Phosphate, PDB code: 7xi2 was solved by P.Yadav, G.S.Kushwaha, N.S.Bhavesh, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	35.61 / 1.65
Space group	P 1
Cell size a, b, c (Å), α, β, γ (°)	40.014, 47.752, 54.074, 106.72, 103.09, 111.02
R / Rfree (%)	15.7 / 18.4

The binding sites of Chlorine atom in the Crystal Structure of Escherichia Coli Adenine Phosphoribosyltransferase (Aprt) in Complex with Phosphate (pdb code 7xi2). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of Escherichia Coli Adenine Phosphoribosyltransferase (Aprt) in Complex with Phosphate, PDB code: 7xi2:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Crystal Structure of Escherichia Coli Adenine Phosphoribosyltransferase (Aprt) in Complex with Phosphate


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Escherichia Coli Adenine Phosphoribosyltransferase (Aprt) in Complex with Phosphate within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl203 b:42.4 occ:1.00 N A:GLY132 2.9 17.6 1.0 N A:ALA130 3.0 15.6 1.0 O A:HOH327 3.2 22.6 1.0 O A:HOH346 3.3 33.8 1.0 N A:THR131 3.4 19.3 1.0 CA A:GLY132 3.4 17.3 1.0 O A:HOH445 3.5 22.1 1.0 CA A:ALA130 3.5 16.5 1.0 C A:ALA130 3.5 16.7 1.0 CB A:ALA130 3.6 18.9 1.0 O A:HOH384 3.8 39.5 1.0 O A:LEU128 4.0 16.4 1.0 C A:LEU129 4.0 14.6 1.0 C A:THR131 4.0 17.8 1.0 C A:GLY132 4.1 15.9 1.0 CA A:LEU129 4.2 14.3 1.0 CD1 A:LEU129 4.3 15.5 1.0 O A:ALA130 4.3 17.3 1.0 CA A:THR131 4.3 18.8 1.0 OG1 A:THR131 4.3 24.5 1.0 N A:GLY133 4.3 15.8 1.0 OG1 A:THR134 4.4 16.3 1.0 C A:LEU128 4.8 13.9 1.0 CB A:THR131 4.9 21.9 1.0 N A:LEU129 5.0 13.9 1.0 O A:GLY132 5.0 15.8 1.0

Chlorine binding site 2 out of 2 in the Crystal Structure of Escherichia Coli Adenine Phosphoribosyltransferase (Aprt) in Complex with Phosphate


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Escherichia Coli Adenine Phosphoribosyltransferase (Aprt) in Complex with Phosphate within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl202 b:32.2 occ:1.00 O B:HOH361 3.0 27.5 1.0 NH1 A:ARG86 3.2 19.7 1.0 NH2 B:ARG66 3.2 35.4 1.0 NE B:ARG66 3.2 31.4 1.0 CZ B:ARG66 3.7 35.6 1.0 CD A:ARG86 3.7 17.7 1.0 CD2 A:LEU91 3.7 19.0 1.0 O A:LYS90 3.8 23.5 1.0 CG2 B:THR32 3.8 20.4 1.0 CD A:PRO92 4.1 21.6 1.0 CA A:LEU91 4.2 17.8 1.0 CZ A:ARG86 4.3 19.0 1.0 C A:LYS90 4.3 22.1 1.0 CD B:ARG66 4.4 25.3 1.0 NE A:ARG86 4.4 17.8 1.0 CG A:LEU91 4.5 17.4 1.0 N A:LEU91 4.5 18.1 1.0 CG B:ARG66 4.7 20.9 1.0 CB A:LEU91 4.9 17.8 1.0 CG A:ARG86 4.9 18.3 1.0

P.Yadav, G.S.Kushwaha, N.S.Bhavesh. Crystal Structure of Escherichia Coli Adenine Phosphoribosyltransferase (Aprt) in Complex with Phosphate To Be Published.