Chlorine in PDB 7ytq: Human Langerin Carbohydrate Recognition Domain in Complex with An Alpha-Mannoside Ligand

The structure of Human Langerin Carbohydrate Recognition Domain in Complex with An Alpha-Mannoside Ligand, PDB code: 7ytq was solved by K.Wangkanont, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.94 / 1.60
Space group	P 42
Cell size a, b, c (Å), α, β, γ (°)	80.03, 80.03, 90.07, 90, 90, 90
R / Rfree (%)	18.3 / 21.3

The structure of Human Langerin Carbohydrate Recognition Domain in Complex with An Alpha-Mannoside Ligand also contains other interesting chemical elements:

Calcium

(Ca)

4 atoms

The binding sites of Chlorine atom in the Human Langerin Carbohydrate Recognition Domain in Complex with An Alpha-Mannoside Ligand (pdb code 7ytq). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the Human Langerin Carbohydrate Recognition Domain in Complex with An Alpha-Mannoside Ligand, PDB code: 7ytq:
Jump to Chlorine binding site number: 1; 2; 3; 4;

Chlorine binding site 1 out of 4 in the Human Langerin Carbohydrate Recognition Domain in Complex with An Alpha-Mannoside Ligand


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Human Langerin Carbohydrate Recognition Domain in Complex with An Alpha-Mannoside Ligand within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl403 b:42.2 occ:0.85 OH A:TYR208 3.0 33.7 1.0 N A:LEU211 3.2 27.6 1.0 CG1 A:ILE212 3.4 38.2 1.0 N A:ILE212 3.6 29.2 1.0 CB A:SER210 3.8 18.5 1.0 CA A:SER210 3.8 17.8 1.0 CE1 A:TYR208 3.8 22.1 1.0 CZ A:TYR208 3.8 35.2 1.0 CD1 A:ILE212 3.9 40.8 1.0 C A:SER210 4.1 20.2 1.0 CA A:LEU211 4.1 30.0 1.0 C A:LEU211 4.3 33.3 1.0 CB A:ILE212 4.4 33.6 1.0 CB A:LEU211 4.4 37.8 1.0 CG2 A:ILE212 4.5 40.7 1.0 CA A:ILE212 4.6 29.4 1.0 OG A:SER210 4.7 19.5 1.0 CZ A:PHE222 4.8 34.3 1.0 O A:ILE212 4.8 26.1 1.0

Chlorine binding site 2 out of 4 in the Human Langerin Carbohydrate Recognition Domain in Complex with An Alpha-Mannoside Ligand


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Human Langerin Carbohydrate Recognition Domain in Complex with An Alpha-Mannoside Ligand within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl403 b:33.6 occ:0.82 OH B:TYR208 2.9 33.1 1.0 N B:LEU211 3.2 23.8 0.5 N B:LEU211 3.2 23.8 0.5 CD1 B:LEU211 3.3 27.2 0.5 CG B:LEU211 3.4 27.4 0.5 N B:ILE212 3.6 26.0 1.0 CG1 B:ILE212 3.6 37.8 1.0 CE1 B:TYR208 3.8 23.8 1.0 CZ B:TYR208 3.8 35.5 1.0 CB B:SER210 4.0 23.8 1.0 CA B:LEU211 4.0 27.3 0.5 CA B:LEU211 4.0 27.3 0.5 CA B:SER210 4.0 20.5 1.0 CB B:LEU211 4.1 28.9 0.5 CB B:ILE212 4.1 29.7 1.0 C B:SER210 4.1 21.8 1.0 C B:LEU211 4.1 29.1 0.5 C B:LEU211 4.1 29.1 0.5 CB B:LEU211 4.2 28.9 0.5 CA B:ILE212 4.4 25.9 1.0 CD2 B:LEU211 4.5 30.5 0.5 CG B:LEU211 4.5 24.6 0.5 CD1 B:ILE212 4.6 35.7 1.0 OG B:SER210 4.7 22.0 1.0 CZ B:PHE222 4.8 33.4 1.0

Chlorine binding site 3 out of 4 in the Human Langerin Carbohydrate Recognition Domain in Complex with An Alpha-Mannoside Ligand


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Human Langerin Carbohydrate Recognition Domain in Complex with An Alpha-Mannoside Ligand within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl404 b:37.9 occ:0.84 OH C:TYR208 2.8 49.2 1.0 N C:LEU211 3.1 29.7 1.0 N C:ILE212 3.6 24.6 1.0 CZ C:TYR208 3.7 35.9 1.0 CE1 C:TYR208 3.9 21.8 1.0 CA C:SER210 3.9 22.5 1.0 CB C:SER210 3.9 21.1 1.0 CA C:LEU211 3.9 28.8 1.0 C C:SER210 4.0 25.3 1.0 CB C:LEU211 4.1 29.8 1.0 C C:LEU211 4.2 32.1 1.0 CB C:ILE212 4.3 30.8 1.0 CG1 C:ILE212 4.4 41.6 1.0 CA C:ILE212 4.5 26.4 1.0 CG C:LEU211 4.7 36.2 1.0 CD1 C:ILE212 4.7 53.5 1.0 OG C:SER210 4.7 23.6 1.0 O C:ILE212 4.9 26.8 1.0 CZ C:PHE222 5.0 35.9 1.0 CE2 C:TYR208 5.0 40.0 1.0

Chlorine binding site 4 out of 4 in the Human Langerin Carbohydrate Recognition Domain in Complex with An Alpha-Mannoside Ligand


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Human Langerin Carbohydrate Recognition Domain in Complex with An Alpha-Mannoside Ligand within 5.0Å range: probe atom residue distance (Å) B Occ D:Cl404 b:30.8 occ:0.69 OH D:TYR208 2.8 41.7 1.0 N D:LEU211 3.3 20.4 1.0 N D:ILE212 3.6 25.8 1.0 CG1 D:ILE212 3.7 41.2 1.0 CB D:SER210 3.8 17.9 1.0 CZ D:TYR208 3.8 32.5 1.0 CE1 D:TYR208 3.9 23.0 1.0 CA D:SER210 3.9 18.2 1.0 CB D:ILE212 4.0 31.6 1.0 CA D:LEU211 4.1 24.6 1.0 C D:SER210 4.1 17.7 1.0 CB D:LEU211 4.2 26.5 1.0 C D:LEU211 4.2 27.1 1.0 CA D:ILE212 4.4 24.8 1.0 OG D:SER210 4.7 18.1 1.0 CG D:LEU211 4.7 35.7 1.0 CZ D:PHE222 4.7 28.4 1.0 O D:ILE212 4.8 25.4 1.0 CZ D:PHE317 4.9 15.6 1.0

K.Wangkanont, K.Wangkanont. N/A N/A.