Chlorine in PDB 7zcb: Human Pikachurin/Egflam N-Terminal Fibronectin-III (1-2) Domains

The structure of Human Pikachurin/Egflam N-Terminal Fibronectin-III (1-2) Domains, PDB code: 7zcb was solved by S.Pantalone, S.Savino, L.V.Viti, F.Forneris, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	46.06 / 2.50
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	70.902, 62.077, 106.863, 90, 104.28, 90
R / Rfree (%)	24.4 / 27.7

The binding sites of Chlorine atom in the Human Pikachurin/Egflam N-Terminal Fibronectin-III (1-2) Domains (pdb code 7zcb). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 5 binding sites of Chlorine where determined in the Human Pikachurin/Egflam N-Terminal Fibronectin-III (1-2) Domains, PDB code: 7zcb:
Jump to Chlorine binding site number: 1; 2; 3; 4; 5;

Chlorine binding site 1 out of 5 in the Human Pikachurin/Egflam N-Terminal Fibronectin-III (1-2) Domains


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Human Pikachurin/Egflam N-Terminal Fibronectin-III (1-2) Domains within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl301 b:104.3 occ:1.00 N C:HIS130 3.2 65.6 1.0 ND1 C:HIS130 3.3 90.3 1.0 CA C:ARG129 3.8 63.8 1.0 CB C:HIS130 3.9 64.5 1.0 C C:ARG129 4.0 61.1 1.0 CG C:HIS130 4.1 78.3 1.0 CA C:HIS130 4.1 62.1 1.0 O C:PRO128 4.3 59.9 1.0 CE1 C:HIS130 4.4 86.3 1.0 CB C:ARG129 4.4 61.2 1.0 O C:HIS130 4.5 64.7 1.0 C C:HIS130 4.8 61.4 1.0 N C:ARG129 4.8 61.3 1.0 CG C:ARG129 5.0 60.9 1.0 C C:PRO128 5.0 63.0 1.0

Chlorine binding site 2 out of 5 in the Human Pikachurin/Egflam N-Terminal Fibronectin-III (1-2) Domains


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Human Pikachurin/Egflam N-Terminal Fibronectin-III (1-2) Domains within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl302 b:58.9 occ:1.00 O C:PRO145 2.9 58.9 1.0 CD1 C:TRP229 3.6 70.0 1.0 NE1 C:TRP229 3.6 63.9 1.0 N C:GLN147 3.7 50.0 1.0 CG C:TRP229 3.8 76.8 1.0 CE2 C:TRP229 3.8 69.4 1.0 N C:TRP229 3.8 46.3 1.0 CA C:GLN146 3.8 51.0 1.0 CD2 C:TRP229 3.8 70.6 1.0 C C:PRO145 3.9 50.6 1.0 C C:GLN146 4.0 49.2 1.0 CA C:SER228 4.2 47.6 1.0 N C:GLN146 4.3 51.3 1.0 CB C:SER228 4.4 46.1 1.0 CZ2 C:TRP229 4.4 71.1 1.0 CB C:TRP229 4.5 55.8 1.0 O C:ALA144 4.5 50.9 1.0 C C:SER228 4.5 45.1 1.0 CA C:GLN147 4.5 48.7 1.0 CE3 C:TRP229 4.6 70.2 1.0 CB C:ALA144 4.6 49.2 1.0 CA C:TRP229 4.8 60.5 1.0 C C:ALA144 4.9 50.4 1.0 O C:GLN146 4.9 47.4 1.0 CB C:GLN147 4.9 50.3 1.0

Chlorine binding site 3 out of 5 in the Human Pikachurin/Egflam N-Terminal Fibronectin-III (1-2) Domains


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Human Pikachurin/Egflam N-Terminal Fibronectin-III (1-2) Domains within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl303 b:60.7 occ:1.00 OE1 C:GLN213 3.5 65.5 1.0 CD C:GLN213 4.6 53.1 1.0 CZ2 C:TRP189 4.7 44.6 1.0 CD1 C:ILE181 4.9 56.5 1.0

Chlorine binding site 4 out of 5 in the Human Pikachurin/Egflam N-Terminal Fibronectin-III (1-2) Domains


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Human Pikachurin/Egflam N-Terminal Fibronectin-III (1-2) Domains within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl304 b:105.8 occ:1.00 CE2 C:PHE185 3.3 70.6 1.0 CZ C:PHE185 3.5 74.4 1.0 OG1 C:THR210 3.5 67.1 1.0 OD2 C:ASP207 4.0 80.0 1.0 CD2 C:PHE185 4.1 67.0 1.0 CG2 C:THR210 4.1 60.1 1.0 CB C:ASP207 4.4 75.1 1.0 CE1 C:PHE185 4.4 74.0 1.0 CB C:THR210 4.5 66.8 1.0 CG C:ASP207 4.5 86.8 1.0 CG C:PHE185 4.9 70.4 1.0

Chlorine binding site 5 out of 5 in the Human Pikachurin/Egflam N-Terminal Fibronectin-III (1-2) Domains


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 5 of Human Pikachurin/Egflam N-Terminal Fibronectin-III (1-2) Domains within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl305 b:46.0 occ:1.00 N C:SER191 3.5 53.3 1.0 NZ C:LYS188 3.5 60.4 1.0 CA C:THR190 4.1 49.0 1.0 CB C:SER191 4.1 53.2 1.0 CG2 C:THR190 4.2 47.8 1.0 C C:THR190 4.3 46.0 1.0 CA C:SER191 4.3 50.8 1.0 OG C:SER191 4.3 45.2 1.0 O C:TRP189 4.4 55.9 1.0 O C:SER191 4.6 54.2 1.0 CE1 C:HIS193 4.7 102.2 1.0 CB C:THR190 4.7 48.7 1.0 NE2 C:HIS193 4.8 106.3 1.0 CE C:LYS188 4.9 60.9 1.0 C C:SER191 5.0 50.5 1.0

D.N.Patil, S.Pantalone, F.Forneris, K.Martemyanov. Structure of the Photoreceptor Synaptic Assembly of the Extracellular Matrix Protein Pikachurin with the Orphan Receptor GPR179 Sci.Signal. 2023.
ISSN: ESSN 1937-9145