Chlorine in PDB 7zgo: Cryo-Em Structure of Human NKCC1 (Tm Domain)

The structure of Cryo-Em Structure of Human NKCC1 (Tm Domain) also contains other interesting chemical elements:

Sodium	(Na)	2 atoms
Potassium	(K)	2 atoms

The binding sites of Chlorine atom in the Cryo-Em Structure of Human NKCC1 (Tm Domain) (pdb code 7zgo). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the Cryo-Em Structure of Human NKCC1 (Tm Domain), PDB code: 7zgo:
Jump to Chlorine binding site number: 1; 2; 3; 4;

Chlorine binding site 1 out of 4 in the Cryo-Em Structure of Human NKCC1 (Tm Domain)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Cryo-Em Structure of Human NKCC1 (Tm Domain) within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1303 b:49.9 occ:1.00 O A:HOH1404 2.8 44.5 1.0 N A:VAL302 3.1 47.7 1.0 N A:MET303 3.3 47.6 1.0 CA A:ALA497 3.4 42.8 1.0 CA A:GLY301 3.5 45.2 1.0 C A:GLY301 3.6 45.2 1.0 CE1 A:TYR383 3.6 45.0 1.0 N A:GLY301 3.7 45.2 1.0 K A:K1302 3.7 41.9 1.0 O A:PRO496 3.7 42.6 1.0 CG A:MET303 3.8 47.6 1.0 CG1 A:VAL302 3.8 47.7 1.0 N A:ALA497 3.8 42.8 1.0 C A:PRO496 3.9 42.6 1.0 O A:ILE299 3.9 42.7 1.0 CB A:MET303 4.0 47.6 1.0 CA A:VAL302 4.0 47.7 1.0 CB A:ALA497 4.0 42.8 1.0 OH A:TYR383 4.0 45.0 1.0 C A:VAL302 4.1 47.7 1.0 CA A:MET303 4.2 47.6 1.0 CZ A:TYR383 4.3 45.0 1.0 C A:ALA497 4.4 42.8 1.0 CB A:VAL302 4.5 47.7 1.0 O A:ALA497 4.5 42.8 1.0 CD1 A:TYR383 4.5 45.0 1.0 O A:GLY301 4.6 45.2 1.0 OH A:TYR533 4.8 42.3 1.0 C A:TRP300 4.9 43.4 1.0 N A:LEU304 4.9 49.0 1.0 CB A:PRO496 5.0 42.6 1.0 CE A:MET382 5.0 47.1 1.0

Chlorine binding site 2 out of 4 in the Cryo-Em Structure of Human NKCC1 (Tm Domain)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Cryo-Em Structure of Human NKCC1 (Tm Domain) within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1304 b:49.8 occ:1.00 OH A:TYR686 2.6 41.4 1.0 N A:GLY500 3.1 45.6 1.0 O A:HOH1411 3.1 51.9 1.0 CA A:GLY500 3.3 45.6 1.0 N A:ILE501 3.4 46.9 1.0 N A:LEU502 3.5 49.8 1.0 CZ A:PHE372 3.5 48.1 1.0 CE1 A:PHE682 3.5 41.9 1.0 C A:GLY500 3.6 45.6 1.0 CZ A:TYR686 3.7 41.4 1.0 CE1 A:PHE372 3.7 48.1 1.0 CE1 A:TYR686 3.8 41.4 1.0 CG A:LEU502 3.8 49.8 1.0 CB A:LEU502 3.9 49.8 1.0 CD1 A:PHE682 3.9 41.9 1.0 CG1 A:ILE501 4.2 46.9 1.0 C A:THR499 4.2 41.9 1.0 CA A:LEU502 4.3 49.8 1.0 CA A:ILE501 4.4 46.9 1.0 C A:ILE501 4.4 46.9 1.0 O A:GLY500 4.5 45.6 1.0 CD1 A:LEU502 4.6 49.8 1.0 O A:HOH1403 4.6 50.2 1.0 CB A:THR499 4.6 41.9 1.0 CA A:THR499 4.6 41.9 1.0 CZ A:PHE682 4.7 41.9 1.0 CE2 A:PHE372 4.8 48.1 1.0 CB A:ILE501 4.9 46.9 1.0 CE2 A:TYR686 4.9 41.4 1.0 CD2 A:LEU502 5.0 49.8 1.0

Chlorine binding site 3 out of 4 in the Cryo-Em Structure of Human NKCC1 (Tm Domain)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Cryo-Em Structure of Human NKCC1 (Tm Domain) within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl1303 b:52.9 occ:1.00 OH B:TYR686 2.7 42.1 1.0 O B:HOH1410 3.0 53.5 1.0 N B:GLY500 3.1 47.1 1.0 N B:ILE501 3.3 48.3 1.0 CA B:GLY500 3.3 47.1 1.0 CZ B:PHE372 3.5 48.7 1.0 N B:LEU502 3.6 52.4 1.0 C B:GLY500 3.6 47.1 1.0 CE1 B:PHE682 3.6 42.2 1.0 CE1 B:PHE372 3.7 48.7 1.0 CZ B:TYR686 3.7 42.1 1.0 CG B:LEU502 3.8 52.4 1.0 CE1 B:TYR686 3.9 42.1 1.0 CB B:LEU502 3.9 52.4 1.0 CD1 B:PHE682 4.0 42.2 1.0 CG1 B:ILE501 4.2 48.3 1.0 C B:THR499 4.3 43.3 1.0 CA B:ILE501 4.3 48.3 1.0 CA B:LEU502 4.3 52.4 1.0 C B:ILE501 4.4 48.3 1.0 O B:GLY500 4.5 47.1 1.0 O B:HOH1403 4.5 50.6 1.0 CD1 B:LEU502 4.6 52.4 1.0 CB B:THR499 4.6 43.3 1.0 CA B:THR499 4.6 43.3 1.0 CZ B:PHE682 4.7 42.2 1.0 CE2 B:PHE372 4.8 48.7 1.0 CB B:ILE501 4.8 48.3 1.0 CD2 B:LEU502 5.0 52.4 1.0 CE2 B:TYR686 5.0 42.1 1.0

Chlorine binding site 4 out of 4 in the Cryo-Em Structure of Human NKCC1 (Tm Domain)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Cryo-Em Structure of Human NKCC1 (Tm Domain) within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl1304 b:50.9 occ:1.00 O B:HOH1404 3.1 45.5 1.0 N B:VAL302 3.2 48.6 1.0 CA B:ALA497 3.4 43.9 1.0 N B:MET303 3.5 48.5 1.0 CA B:GLY301 3.5 46.6 1.0 CE1 B:TYR383 3.6 45.7 1.0 CG B:MET303 3.6 48.5 1.0 C B:GLY301 3.7 46.6 1.0 K B:K1302 3.7 43.5 1.0 N B:GLY301 3.7 46.6 1.0 O B:PRO496 3.7 43.4 1.0 N B:ALA497 3.8 43.9 1.0 CG1 B:VAL302 3.9 48.6 1.0 OH B:TYR383 3.9 45.7 1.0 C B:PRO496 4.0 43.4 1.0 O B:ILE299 4.0 43.9 1.0 CB B:ALA497 4.0 43.9 1.0 CB B:MET303 4.0 48.5 1.0 CA B:VAL302 4.2 48.6 1.0 CZ B:TYR383 4.2 45.7 1.0 C B:VAL302 4.3 48.6 1.0 CA B:MET303 4.4 48.5 1.0 C B:ALA497 4.4 43.9 1.0 O B:ALA497 4.5 43.9 1.0 CD1 B:TYR383 4.6 45.7 1.0 CB B:VAL302 4.6 48.6 1.0 O B:GLY301 4.7 46.6 1.0 CE B:MET382 4.8 47.2 1.0 C B:TRP300 4.9 43.2 1.0 OH B:TYR533 4.9 42.1 1.0 N B:LEU304 4.9 48.8 1.0 CB B:PRO496 5.0 43.4 1.0

P.Nissen, R.Fenton, C.Neumann, L.Lindtoft Rosenbaek, R.Kock Flygaard, M.Habeck, J.Lykkegaard Karlsen, Y.Wang, K.Lindorff-Larsen, H.Gad, R.Hartmann, J.Lyons. Cryo-Em Structure of Human NKCC1 (Tm Domain) To Be Published.