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Chlorine in PDB 7zvl: Human PRMT5:MEP50 Crystal Structure with Mta and Fragment BoundEnzymatic activity of Human PRMT5:MEP50 Crystal Structure with Mta and Fragment Bound
All present enzymatic activity of Human PRMT5:MEP50 Crystal Structure with Mta and Fragment Bound:
2.1.1.320; Protein crystallography data
The structure of Human PRMT5:MEP50 Crystal Structure with Mta and Fragment Bound, PDB code: 7zvl
was solved by
M.U.Ahmad,
W.Koelmel,
V.Arkhipova,
J.D.Lawson,
C.R.Smith,
R.J.Gunn,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Human PRMT5:MEP50 Crystal Structure with Mta and Fragment Bound
(pdb code 7zvl). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Human PRMT5:MEP50 Crystal Structure with Mta and Fragment Bound, PDB code: 7zvl: Chlorine binding site 1 out of 1 in 7zvlGo back to Chlorine Binding Sites List in 7zvl
Chlorine binding site 1 out
of 1 in the Human PRMT5:MEP50 Crystal Structure with Mta and Fragment Bound
Mono view Stereo pair view
Reference:
C.R.Smith,
S.Kulyk,
M.U.D.Ahmad,
V.Arkhipova,
J.G.Christensen,
R.J.Gunn,
A.Ivetac,
J.M.Ketcham,
J.Kuehler,
J.D.Lawson,
N.C.Thomas,
X.Wang,
M.A.Marx.
Fragment Optimization and Elaboration Strategies - the Discovery of Two Lead Series of PRMT5/Mta Inhibitors From Five Fragment Hits Rsc Med Chem 2022.
Page generated: Tue Apr 4 22:26:30 2023
ISSN: ESSN 2632-8682 DOI: 10.1039/D2MD00163B |
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