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Chlorine in PDB 8a6h: Small Molecule Stabilizer (Compound 7) For C-Raf and 14-3-3Enzymatic activity of Small Molecule Stabilizer (Compound 7) For C-Raf and 14-3-3
All present enzymatic activity of Small Molecule Stabilizer (Compound 7) For C-Raf and 14-3-3:
2.7.11.1; Protein crystallography data
The structure of Small Molecule Stabilizer (Compound 7) For C-Raf and 14-3-3, PDB code: 8a6h
was solved by
D.N.Kenanova,
E.J.Visser,
J.Virta,
E.Sijbesma,
F.Centorrino,
M.Zhong,
H.Vickery,
J.Neitz,
L.Brunsveld,
C.Ottmann,
M.R.Arkin,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 8a6h:
The structure of Small Molecule Stabilizer (Compound 7) For C-Raf and 14-3-3 also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Small Molecule Stabilizer (Compound 7) For C-Raf and 14-3-3
(pdb code 8a6h). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Small Molecule Stabilizer (Compound 7) For C-Raf and 14-3-3, PDB code: 8a6h: Chlorine binding site 1 out of 1 in 8a6hGo back to Chlorine Binding Sites List in 8a6h
Chlorine binding site 1 out
of 1 in the Small Molecule Stabilizer (Compound 7) For C-Raf and 14-3-3
Mono view Stereo pair view
Reference:
D.N.Kenanova,
E.J.Visser,
J.M.Virta,
E.Sijbesma,
F.Centorrino,
H.R.Vickery,
M.Zhong,
R.J.Neitz,
L.Brunsveld,
C.Ottmann,
M.R.Arkin.
A Systematic Approach to the Discovery of Protein–Protein Interaction Stabilizers Acs Cent.Sci. 2023.
Page generated: Wed Jul 26 15:22:04 2023
ISSN: ESSN 2374-7951 DOI: 10.1021/ACSCENTSCI.2C01449 |
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