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Atomistry » Chlorine » PDB 8aka-8aro » 8aqf » |
Chlorine in PDB 8aqf: Crystal Structure of Human Monoglyceride Lipase with Compound Lei-515Enzymatic activity of Crystal Structure of Human Monoglyceride Lipase with Compound Lei-515
All present enzymatic activity of Crystal Structure of Human Monoglyceride Lipase with Compound Lei-515:
3.1.1.23; Protein crystallography data
The structure of Crystal Structure of Human Monoglyceride Lipase with Compound Lei-515, PDB code: 8aqf
was solved by
M.Jiang,
M.Huizenga,
J.Wirt,
J.Paloczi,
A.Amedi,
R.Van Der Berg,
J.Benz,
L.Collin,
H.Deng,
W.Driever,
B.Florea,
U.Grether,
A.Janssen,
L.Heitman,
T.W.Lam,
F.Mohr,
A.Pavlovic,
I.Ruf,
H.Rutjes,
F.Stevens,
D.Van Der Vliet,
T.Van Der Wel,
M.Wittwer,
C.Boeckel,
P.Pacher,
A.Hohmann,
M.Van Der Stelt,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 8aqf:
The structure of Crystal Structure of Human Monoglyceride Lipase with Compound Lei-515 also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of Human Monoglyceride Lipase with Compound Lei-515
(pdb code 8aqf). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of Human Monoglyceride Lipase with Compound Lei-515, PDB code: 8aqf: Jump to Chlorine binding site number: 1; 2; Chlorine binding site 1 out of 2 in 8aqfGo back to Chlorine Binding Sites List in 8aqf
Chlorine binding site 1 out
of 2 in the Crystal Structure of Human Monoglyceride Lipase with Compound Lei-515
Mono view Stereo pair view
Chlorine binding site 2 out of 2 in 8aqfGo back to Chlorine Binding Sites List in 8aqf
Chlorine binding site 2 out
of 2 in the Crystal Structure of Human Monoglyceride Lipase with Compound Lei-515
Mono view Stereo pair view
Reference:
M.Jiang,
M.Van Der Stelt.
Discovery of A Peripheral Restricted, Reversible Monoacylglycerol Lipase Inhibitor That Reduces Liver Injury and Chemotherapy-Induced Neuropathy To Be Published.
Page generated: Thu Dec 28 03:00:36 2023
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