Chlorine in PDB 8bf4: Crystal Structure of Mouse Plexin-B1 (20-535) in Complex with VHH15 and VHH14

The structure of Crystal Structure of Mouse Plexin-B1 (20-535) in Complex with VHH15 and VHH14, PDB code: 8bf4 was solved by R.Cowan, G.Hall, M.Carr, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	95.26 / 2.15
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	95.267, 109.233, 95.478, 90, 90.7, 90
R / Rfree (%)	21.1 / 22.8

The binding sites of Chlorine atom in the Crystal Structure of Mouse Plexin-B1 (20-535) in Complex with VHH15 and VHH14 (pdb code 8bf4). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Mouse Plexin-B1 (20-535) in Complex with VHH15 and VHH14, PDB code: 8bf4:

Chlorine binding site 1 out of 1 in the Crystal Structure of Mouse Plexin-B1 (20-535) in Complex with VHH15 and VHH14


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Mouse Plexin-B1 (20-535) in Complex with VHH15 and VHH14 within 5.0Å range: probe atom residue distance (Å) B Occ F:Cl605 b:47.4 occ:1.00 O F:HOH830 2.8 38.3 1.0 N F:TYR358 3.0 37.0 1.0 NZ F:LYS238 3.4 45.2 1.0 NH2 F:ARG234 3.5 27.5 1.0 O F:HOH706 3.7 44.4 1.0 CA F:ALA357 3.8 35.0 1.0 CA F:TYR358 3.9 39.8 1.0 C F:ALA357 3.9 34.6 1.0 NH1 F:ARG234 4.0 29.5 1.0 CZ F:ARG234 4.2 26.0 1.0 CG1 F:VAL387 4.2 29.2 1.0 CB F:ALA357 4.4 33.0 1.0 CE F:LYS238 4.5 46.5 1.0 O F:ILE356 4.5 37.7 1.0 CD F:LYS238 4.6 43.3 1.0 O F:TYR358 4.6 47.6 1.0 C F:TYR358 4.7 45.6 1.0 CB F:VAL387 4.8 30.5 1.0 OH F:TYR214 4.9 42.6 1.0 CE1 F:TYR214 4.9 37.1 1.0 CG2 F:VAL387 4.9 23.0 1.0 CD1 F:TYR358 4.9 33.6 1.0 CG F:TYR358 4.9 35.8 1.0 N F:ALA357 5.0 38.5 1.0

R.Cowan, M.Trokter, A.Oleksy, M.Fedorova, K.Sawmynaden, T.Worzfeld, S.Offermanns, D.Matthews, M.D.Carr, G.Hall. Nanobody Inhibitors of Plexin-B1 Identify Allostery in Plexin-Semaphorin Interactions and Signalling. J.Biol.Chem. 04740 2023.
ISSN: ESSN 1083-351X
PubMed: 37088134
DOI: 10.1016/J.JBC.2023.104740