Chlorine in PDB 8bre: 1,6-Anhydro-N-Actetylmuramic Acid Kinase (Anmk)

All present enzymatic activity of 1,6-Anhydro-N-Actetylmuramic Acid Kinase (Anmk):
2.7.1.170;

The structure of 1,6-Anhydro-N-Actetylmuramic Acid Kinase (Anmk), PDB code: 8bre was solved by E.Jimenez-Faraco, J.A.Hermoso, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	47.29 / 2.00
Space group	P 63
Cell size a, b, c (Å), α, β, γ (°)	90.093, 90.093, 178.378, 90, 90, 120
R / Rfree (%)	17.8 / 21.2

The binding sites of Chlorine atom in the 1,6-Anhydro-N-Actetylmuramic Acid Kinase (Anmk) (pdb code 8bre). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the 1,6-Anhydro-N-Actetylmuramic Acid Kinase (Anmk), PDB code: 8bre:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the 1,6-Anhydro-N-Actetylmuramic Acid Kinase (Anmk)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of 1,6-Anhydro-N-Actetylmuramic Acid Kinase (Anmk) within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl401 b:70.0 occ:1.00 N A:LEU142 3.1 46.0 1.0 NH2 A:ARG129 3.6 44.1 1.0 CA A:PRO141 3.6 45.9 1.0 NH1 A:ARG129 3.7 45.3 1.0 CB A:PRO141 3.8 49.1 1.0 C A:PRO141 3.9 46.9 1.0 N A:VAL143 4.1 42.0 1.0 CZ A:ARG129 4.1 47.2 1.0 CA A:LEU142 4.1 42.9 1.0 CG1 A:VAL143 4.2 44.8 1.0 CB A:LEU142 4.2 44.2 1.0 CG2 A:VAL143 4.5 42.9 1.0 O A:HOH587 4.5 36.8 1.0 C A:LEU142 4.5 43.4 1.0 OE2 A:GLU326 4.7 58.2 1.0 CB A:VAL143 4.8 45.2 1.0 CG A:LEU142 4.8 41.8 1.0 CE2 A:PHE330 4.8 42.9 1.0 CZ A:PHE330 4.9 42.2 1.0 N A:PRO141 4.9 46.0 1.0

Chlorine binding site 2 out of 2 in the 1,6-Anhydro-N-Actetylmuramic Acid Kinase (Anmk)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of 1,6-Anhydro-N-Actetylmuramic Acid Kinase (Anmk) within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl401 b:68.8 occ:1.00 NH2 B:ARG129 2.7 54.7 1.0 N B:LEU142 3.1 48.5 1.0 CA B:PRO141 3.7 50.6 1.0 CZ B:ARG129 3.8 51.6 1.0 C B:PRO141 3.9 49.5 1.0 NH1 B:ARG129 4.0 56.5 1.0 CB B:LEU142 4.0 46.5 1.0 CB B:PRO141 4.0 49.6 1.0 CA B:LEU142 4.1 47.0 1.0 N B:VAL143 4.2 48.0 1.0 CG1 B:VAL143 4.4 49.5 1.0 OE2 B:GLU326 4.5 71.1 1.0 CG B:LEU142 4.5 43.1 1.0 C B:LEU142 4.6 48.9 1.0 CG2 B:VAL143 4.7 50.2 1.0 CE1 B:PHE330 4.8 41.1 1.0 CZ B:PHE330 4.8 41.3 1.0 CB B:ALA140 4.8 46.0 1.0 NE B:ARG129 4.9 54.9 1.0 CA B:ALA140 5.0 44.9 1.0 CB B:VAL143 5.0 49.3 1.0

A.M.El-Araby, E.Jimenez-Faraco, R.Feltzer, J.M.Martin-Garcia, B.R.Karri, B.Ramachandran, C.Kim, J.F.Fisher, J.A.Hermoso, S.Mobashery. Catalytic Process of Anhydro-N-Acetylmuramic Acid Kinase (Anmk) From Pseudomonas Aeruginosa. J.Biol.Chem. 05198 2023.
ISSN: ESSN 1083-351X
PubMed: 37660917
DOI: 10.1016/J.JBC.2023.105198