Chlorine in PDB 8bzw: Co-Soaked Stabilizers For Era - 14-3-3 Interaction (844_AZ210)

The structure of Co-Soaked Stabilizers For Era - 14-3-3 Interaction (844_AZ210), PDB code: 8bzw was solved by E.J.Visser, E.Sijbesma, C.Ottmann, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	45.34 / 1.10
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	81.806, 112.014, 62.335, 90, 90, 90
R / Rfree (%)	17.8 / 19.3

The structure of Co-Soaked Stabilizers For Era - 14-3-3 Interaction (844_AZ210) also contains other interesting chemical elements:

Magnesium

(Mg)

3 atoms

The binding sites of Chlorine atom in the Co-Soaked Stabilizers For Era - 14-3-3 Interaction (844_AZ210) (pdb code 8bzw). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Co-Soaked Stabilizers For Era - 14-3-3 Interaction (844_AZ210), PDB code: 8bzw:

Chlorine binding site 1 out of 1 in the Co-Soaked Stabilizers For Era - 14-3-3 Interaction (844_AZ210)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Co-Soaked Stabilizers For Era - 14-3-3 Interaction (844_AZ210) within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl305 b:18.0 occ:1.00 CL1 A:GEH305 0.0 18.0 1.0 C02 A:GEH305 1.8 14.8 1.0 C17 A:GEH305 2.7 16.5 1.0 C03 A:GEH305 2.7 14.7 1.0 H14 A:GEH305 2.8 19.8 1.0 HE3 A:LYS122 2.8 12.6 1.0 H1 A:GEH305 2.9 17.7 1.0 HD3 A:LYS122 2.9 11.7 1.0 HA A:ILE168 3.1 11.8 1.0 HG23 A:ILE168 3.3 14.3 1.0 HZ2 A:LYS122 3.4 13.3 1.0 CE A:LYS122 3.5 10.5 1.0 CD A:LYS122 3.5 9.7 1.0 HG12 A:ILE168 3.5 15.2 1.0 HE2 A:PHE119 3.6 19.5 1.0 HD2 A:LYS122 3.6 11.7 1.0 HG23 B:VAL595 3.8 15.9 1.0 HD2 A:PHE119 3.8 16.5 1.0 HA3 A:GLY171 3.9 11.8 1.0 NZ A:LYS122 3.9 11.1 1.0 CE2 A:PHE119 4.0 16.2 1.0 C16 A:GEH305 4.0 17.3 1.0 CA A:ILE168 4.0 9.8 1.0 C04 A:GEH305 4.0 14.8 1.0 CD2 A:PHE119 4.1 13.7 1.0 HZ1 A:LYS122 4.2 13.3 1.0 CG2 A:ILE168 4.2 11.9 1.0 O A:ILE168 4.3 10.4 1.0 CG1 A:ILE168 4.3 12.7 1.0 HE2 A:LYS122 4.4 12.6 1.0 CB A:ILE168 4.4 11.2 1.0 C05 A:GEH305 4.5 14.8 1.0 CG2 B:VAL595 4.6 13.2 1.0 H A:LEU172 4.7 10.5 1.0 HZ3 A:LYS122 4.7 13.3 1.0 HG21 B:VAL595 4.7 15.9 1.0 O A:PRO167 4.7 10.4 1.0 HG21 A:ILE168 4.7 14.3 1.0 C A:ILE168 4.7 9.5 1.0 HG13 A:ILE168 4.7 15.2 1.0 CA A:GLY171 4.7 9.8 1.0 HA A:PHE119 4.8 9.9 1.0 H13 A:GEH305 4.8 20.8 1.0 HG22 A:ILE168 4.8 14.3 1.0 H A:GLY171 4.9 10.7 1.0 H7 A:GEH305 4.9 17.7 1.0 N A:LEU172 4.9 8.8 1.0 CG A:LYS122 4.9 9.0 1.0 CZ A:PHE119 4.9 12.2 1.0 N A:ILE168 4.9 9.6 1.0 C A:GLY171 5.0 9.2 1.0

E.J.Visser, P.Jaishankar, E.Sijbesma, M.A.M.Pennings, E.M.F.Vandenboorn, X.Guillory, R.J.Neitz, J.Morrow, S.Dutta, A.R.Renslo, L.Brunsveld, M.R.Arkin, C.Ottmann. From Tethered to Freestanding Stabilizers of 14-3-3 Protein-Protein Interactions Via Fragment Linking. Angew.Chem.Int.Ed.Engl. 08004 2023.
ISSN: ESSN 1521-3773
PubMed: 37455289
DOI: 10.1002/ANIE.202308004