Chlorine in PDB 8c7m: Interleukin 12 Receptor Subunit Beta-1 Fn Domains in Complex with Antagonistic Fab Fragment.

The structure of Interleukin 12 Receptor Subunit Beta-1 Fn Domains in Complex with Antagonistic Fab Fragment., PDB code: 8c7m was solved by Y.Bloch, S.N.Savvides, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	70.09 / 2.56
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	73.663, 140.178, 219.363, 90, 90, 90
R / Rfree (%)	20.3 / 22.8

The binding sites of Chlorine atom in the Interleukin 12 Receptor Subunit Beta-1 Fn Domains in Complex with Antagonistic Fab Fragment. (pdb code 8c7m). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Interleukin 12 Receptor Subunit Beta-1 Fn Domains in Complex with Antagonistic Fab Fragment., PDB code: 8c7m:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Interleukin 12 Receptor Subunit Beta-1 Fn Domains in Complex with Antagonistic Fab Fragment.


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Interleukin 12 Receptor Subunit Beta-1 Fn Domains in Complex with Antagonistic Fab Fragment. within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl605 b:113.2 occ:1.00 NH1 A:ARG484 3.4 99.8 1.0 NE1 A:TRP531 3.7 92.1 1.0 NH1 A:ARG528 4.1 116.2 1.0 CD1 A:TRP531 4.1 76.7 1.0 NH2 A:ARG484 4.1 104.7 1.0 CZ A:ARG484 4.2 101.4 1.0 CE2 A:TRP531 4.9 84.7 1.0

Chlorine binding site 2 out of 2 in the Interleukin 12 Receptor Subunit Beta-1 Fn Domains in Complex with Antagonistic Fab Fragment.


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Interleukin 12 Receptor Subunit Beta-1 Fn Domains in Complex with Antagonistic Fab Fragment. within 5.0Å range: probe atom residue distance (Å) B Occ H:Cl301 b:92.5 occ:1.00 NH2 H:ARG98 3.4 73.8 1.0 NE2 A:HIS423 3.5 88.6 1.0 CE1 A:HIS423 3.9 86.7 1.0 OH H:TYR32 4.2 74.9 1.0 CZ H:ARG98 4.4 77.3 1.0 NH1 H:ARG98 4.4 84.6 1.0 CD2 A:HIS423 4.7 81.4 1.0 CE2 H:TYR32 4.8 84.4 1.0 CE2 H:TYR110 4.8 67.3 1.0 OD2 H:ASP109 4.9 100.7 1.0 CZ H:TYR32 4.9 79.0 1.0

Y.Bloch, S.N.Savvides. Interleukin 12 Receptor Subunit Beta-1 Fn Domains in Complex with Antagonistic Fab Fragment. To Be Published.