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Atomistry » Chlorine » PDB 8c6t-8chn » 8cb6 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 8c6t-8chn » 8cb6 » |
Chlorine in PDB 8cb6: Crystal Structure of Human Lysosomal Acid-Alpha-Glucosidase, Gaa, in Covalent Complex with Tamra Tagged 1,6-Epi-Cylcophellitol Aziridine Activity Based ProbeProtein crystallography data
The structure of Crystal Structure of Human Lysosomal Acid-Alpha-Glucosidase, Gaa, in Covalent Complex with Tamra Tagged 1,6-Epi-Cylcophellitol Aziridine Activity Based Probe, PDB code: 8cb6
was solved by
G.Sulzenbacher,
V.Roig-Zamboni,
H.Overkleeft,
M.Artola,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of Human Lysosomal Acid-Alpha-Glucosidase, Gaa, in Covalent Complex with Tamra Tagged 1,6-Epi-Cylcophellitol Aziridine Activity Based Probe
(pdb code 8cb6). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 10 binding sites of Chlorine where determined in the Crystal Structure of Human Lysosomal Acid-Alpha-Glucosidase, Gaa, in Covalent Complex with Tamra Tagged 1,6-Epi-Cylcophellitol Aziridine Activity Based Probe, PDB code: 8cb6: Jump to Chlorine binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10; Chlorine binding site 1 out of 10 in 8cb6Go back to Chlorine Binding Sites List in 8cb6
Chlorine binding site 1 out
of 10 in the Crystal Structure of Human Lysosomal Acid-Alpha-Glucosidase, Gaa, in Covalent Complex with Tamra Tagged 1,6-Epi-Cylcophellitol Aziridine Activity Based Probe
Mono view Stereo pair view
Chlorine binding site 2 out of 10 in 8cb6Go back to Chlorine Binding Sites List in 8cb6
Chlorine binding site 2 out
of 10 in the Crystal Structure of Human Lysosomal Acid-Alpha-Glucosidase, Gaa, in Covalent Complex with Tamra Tagged 1,6-Epi-Cylcophellitol Aziridine Activity Based Probe
Mono view Stereo pair view
Chlorine binding site 3 out of 10 in 8cb6Go back to Chlorine Binding Sites List in 8cb6
Chlorine binding site 3 out
of 10 in the Crystal Structure of Human Lysosomal Acid-Alpha-Glucosidase, Gaa, in Covalent Complex with Tamra Tagged 1,6-Epi-Cylcophellitol Aziridine Activity Based Probe
Mono view Stereo pair view
Chlorine binding site 4 out of 10 in 8cb6Go back to Chlorine Binding Sites List in 8cb6
Chlorine binding site 4 out
of 10 in the Crystal Structure of Human Lysosomal Acid-Alpha-Glucosidase, Gaa, in Covalent Complex with Tamra Tagged 1,6-Epi-Cylcophellitol Aziridine Activity Based Probe
Mono view Stereo pair view
Chlorine binding site 5 out of 10 in 8cb6Go back to Chlorine Binding Sites List in 8cb6
Chlorine binding site 5 out
of 10 in the Crystal Structure of Human Lysosomal Acid-Alpha-Glucosidase, Gaa, in Covalent Complex with Tamra Tagged 1,6-Epi-Cylcophellitol Aziridine Activity Based Probe
Mono view Stereo pair view
Chlorine binding site 6 out of 10 in 8cb6Go back to Chlorine Binding Sites List in 8cb6
Chlorine binding site 6 out
of 10 in the Crystal Structure of Human Lysosomal Acid-Alpha-Glucosidase, Gaa, in Covalent Complex with Tamra Tagged 1,6-Epi-Cylcophellitol Aziridine Activity Based Probe
Mono view Stereo pair view
Chlorine binding site 7 out of 10 in 8cb6Go back to Chlorine Binding Sites List in 8cb6
Chlorine binding site 7 out
of 10 in the Crystal Structure of Human Lysosomal Acid-Alpha-Glucosidase, Gaa, in Covalent Complex with Tamra Tagged 1,6-Epi-Cylcophellitol Aziridine Activity Based Probe
Mono view Stereo pair view
Chlorine binding site 8 out of 10 in 8cb6Go back to Chlorine Binding Sites List in 8cb6
Chlorine binding site 8 out
of 10 in the Crystal Structure of Human Lysosomal Acid-Alpha-Glucosidase, Gaa, in Covalent Complex with Tamra Tagged 1,6-Epi-Cylcophellitol Aziridine Activity Based Probe
Mono view Stereo pair view
Chlorine binding site 9 out of 10 in 8cb6Go back to Chlorine Binding Sites List in 8cb6
Chlorine binding site 9 out
of 10 in the Crystal Structure of Human Lysosomal Acid-Alpha-Glucosidase, Gaa, in Covalent Complex with Tamra Tagged 1,6-Epi-Cylcophellitol Aziridine Activity Based Probe
Mono view Stereo pair view
Chlorine binding site 10 out of 10 in 8cb6Go back to Chlorine Binding Sites List in 8cb6
Chlorine binding site 10 out
of 10 in the Crystal Structure of Human Lysosomal Acid-Alpha-Glucosidase, Gaa, in Covalent Complex with Tamra Tagged 1,6-Epi-Cylcophellitol Aziridine Activity Based Probe
Mono view Stereo pair view
Reference:
D.Van Der Gracht,
R.J.Rowland,
V.Roig-Zamboni,
M.J.Ferraz,
M.Louwerse,
P.P.Geurink,
J.M.F.G.Aerts,
G.Sulzenbacher,
G.J.Davies,
H.S.Overkleeft,
M.Artola.
Fluorescence Polarisation Activity-Based Protein Profiling For the Identification of Deoxynojirimycin-Type Inhibitors Selective For Lysosomal Retaining Alpha- and Beta-Glucosidases. Chem Sci V. 14 9136 2023.
Page generated: Thu Dec 28 03:08:12 2023
ISSN: ISSN 2041-6520 PubMed: 37655021 DOI: 10.1039/D3SC01021J |
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