Chlorine in PDB 8cc6: Mouse Serotonin 5-HT3A Receptor in Complex with Pz-1922

The binding sites of Chlorine atom in the Mouse Serotonin 5-HT3A Receptor in Complex with Pz-1922 (pdb code 8cc6). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 5 binding sites of Chlorine where determined in the Mouse Serotonin 5-HT3A Receptor in Complex with Pz-1922, PDB code: 8cc6:
Jump to Chlorine binding site number: 1; 2; 3; 4; 5;

Chlorine binding site 1 out of 5 in the Mouse Serotonin 5-HT3A Receptor in Complex with Pz-1922


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Mouse Serotonin 5-HT3A Receptor in Complex with Pz-1922 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl502 b:63.8 occ:1.00 CL01 A:U9L502 0.0 63.8 1.0 C02 A:U9L502 1.7 34.2 1.0 C03 A:U9L502 2.7 28.4 1.0 C27 A:U9L502 2.7 31.5 1.0 OG A:SER179 2.8 57.5 1.0 CD1 B:ILE201 3.5 56.0 1.0 CD1 A:ILE44 3.6 32.2 1.0 CG2 A:ILE180 3.7 38.9 1.0 CB A:SER179 3.9 57.6 1.0 C04 A:U9L502 3.9 27.6 1.0 C06 A:U9L502 4.0 33.0 1.0 C05 A:U9L502 4.5 29.9 1.0 CG2 A:ILE44 4.6 35.8 1.0 CG1 A:ILE44 4.8 32.3 1.0 N A:ILE180 4.8 48.5 1.0 CB A:ILE180 4.9 37.8 1.0 CG1 B:ILE201 4.9 60.5 1.0 CG1 A:ILE180 4.9 40.8 1.0 CD1 A:ILE180 5.0 40.8 1.0

Chlorine binding site 2 out of 5 in the Mouse Serotonin 5-HT3A Receptor in Complex with Pz-1922


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Mouse Serotonin 5-HT3A Receptor in Complex with Pz-1922 within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl502 b:60.2 occ:1.00 CL01 B:U9L502 0.0 60.2 1.0 C02 B:U9L502 1.7 32.3 1.0 C03 B:U9L502 2.7 30.6 1.0 C27 B:U9L502 2.7 30.1 1.0 OG B:SER179 2.8 51.2 1.0 CD1 B:ILE44 3.4 29.6 1.0 CD1 C:ILE201 3.5 61.9 1.0 CG2 B:ILE180 3.7 36.7 1.0 CB B:SER179 3.9 53.8 1.0 C04 B:U9L502 3.9 33.1 1.0 C06 B:U9L502 4.0 32.0 1.0 C05 B:U9L502 4.5 31.6 1.0 N B:ILE180 4.7 48.7 1.0 CG1 B:ILE44 4.8 21.1 1.0 CB B:ILE180 4.9 37.8 1.0 CG2 B:ILE44 5.0 26.2 1.0

Chlorine binding site 3 out of 5 in the Mouse Serotonin 5-HT3A Receptor in Complex with Pz-1922


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Mouse Serotonin 5-HT3A Receptor in Complex with Pz-1922 within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl502 b:57.8 occ:1.00 CL01 C:U9L502 0.0 57.8 1.0 C02 C:U9L502 1.7 29.4 1.0 C03 C:U9L502 2.7 27.3 1.0 C27 C:U9L502 2.7 32.5 1.0 OG C:SER179 2.8 58.0 1.0 CD1 D:ILE201 3.5 57.6 1.0 CD1 C:ILE44 3.6 29.6 1.0 CG2 C:ILE180 3.8 41.1 1.0 CB C:SER179 3.9 58.1 1.0 C04 C:U9L502 3.9 30.1 1.0 C06 C:U9L502 4.0 33.1 1.0 C05 C:U9L502 4.5 27.1 1.0 CG2 C:ILE44 4.6 19.7 1.0 N C:ILE180 4.8 47.6 1.0 CG1 C:ILE44 4.9 31.6 1.0 CB C:ILE180 4.9 40.3 1.0 CG1 C:ILE180 4.9 36.9 1.0 CG1 D:ILE201 5.0 60.3 1.0 CD1 C:ILE180 5.0 36.1 1.0

Chlorine binding site 4 out of 5 in the Mouse Serotonin 5-HT3A Receptor in Complex with Pz-1922


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Mouse Serotonin 5-HT3A Receptor in Complex with Pz-1922 within 5.0Å range: probe atom residue distance (Å) B Occ D:Cl502 b:57.8 occ:1.00 CL01 D:U9L502 0.0 57.8 1.0 C02 D:U9L502 1.7 30.0 1.0 C03 D:U9L502 2.7 31.1 1.0 C27 D:U9L502 2.7 28.9 1.0 OG D:SER179 2.9 53.8 1.0 CD1 D:ILE44 3.4 28.8 1.0 CG2 D:ILE180 3.5 36.6 1.0 CD1 E:ILE201 3.5 55.9 1.0 C04 D:U9L502 3.9 31.1 1.0 C06 D:U9L502 4.0 30.8 1.0 CB D:SER179 4.0 53.8 1.0 C05 D:U9L502 4.5 28.0 1.0 N D:ILE180 4.7 46.5 1.0 CG1 D:ILE44 4.8 22.9 1.0 CB D:ILE180 4.9 38.3 1.0

Chlorine binding site 5 out of 5 in the Mouse Serotonin 5-HT3A Receptor in Complex with Pz-1922


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 5 of Mouse Serotonin 5-HT3A Receptor in Complex with Pz-1922 within 5.0Å range: probe atom residue distance (Å) B Occ E:Cl1001 b:64.5 occ:1.00 CL01 E:U9L1001 0.0 64.5 1.0 C02 E:U9L1001 1.7 31.3 1.0 C03 E:U9L1001 2.7 29.5 1.0 C27 E:U9L1001 2.7 31.4 1.0 OG E:SER179 2.8 53.8 1.0 CD1 E:ILE44 3.4 28.5 1.0 CD1 A:ILE201 3.5 56.5 1.0 CG2 E:ILE180 3.7 37.6 1.0 CB E:SER179 3.8 54.0 1.0 C04 E:U9L1001 3.9 30.0 1.0 C06 E:U9L1001 4.0 32.8 1.0 C05 E:U9L1001 4.5 29.1 1.0 N E:ILE180 4.7 48.1 1.0 CG1 E:ILE44 4.8 21.6 1.0 CB E:ILE180 5.0 39.6 1.0 CG1 A:ILE201 5.0 60.8 1.0

U.Lopez-Sanchez, H.Nury. Triple-Acting Mao-B Inhibitor and 5-HT6R/5-HT3R Antagonist J.Med.Chem. 2023.
ISSN: ISSN 0022-2623
DOI: 10.1021/ACS.JMEDCHEM.3C01482