Chlorine in PDB 8dzr: GR89,696 Bound Kappa Opioid Receptor in Complex with Ggustducin

The binding sites of Chlorine atom in the GR89,696 Bound Kappa Opioid Receptor in Complex with Ggustducin (pdb code 8dzr). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the GR89,696 Bound Kappa Opioid Receptor in Complex with Ggustducin, PDB code: 8dzr:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the GR89,696 Bound Kappa Opioid Receptor in Complex with Ggustducin


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of GR89,696 Bound Kappa Opioid Receptor in Complex with Ggustducin within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl401 b:62.4 occ:1.00 CL1 A:U9I401 0.0 62.4 1.0 C10 A:U9I401 1.7 62.4 1.0 C9 A:U9I401 2.7 62.4 1.0 C11 A:U9I401 2.7 62.4 1.0 CL2 A:U9I401 3.2 62.4 1.0 O A:CYS210 3.9 65.9 1.0 C8 A:U9I401 4.0 62.4 1.0 C12 A:U9I401 4.0 62.4 1.0 O A:PHE114 4.2 72.5 1.0 SG A:CYS210 4.3 65.9 1.0 CB A:CYS210 4.4 65.9 1.0 CG A:GLN115 4.4 71.2 1.0 CD1 A:LEU135 4.5 59.7 1.0 C7 A:U9I401 4.5 62.4 1.0 CZ3 A:TRP124 4.5 67.7 1.0 NE2 A:GLN115 4.8 71.2 1.0 C A:CYS210 4.9 65.9 1.0 CG2 A:VAL118 4.9 67.4 1.0

Chlorine binding site 2 out of 2 in the GR89,696 Bound Kappa Opioid Receptor in Complex with Ggustducin


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of GR89,696 Bound Kappa Opioid Receptor in Complex with Ggustducin within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl401 b:62.4 occ:1.00 CL2 A:U9I401 0.0 62.4 1.0 C11 A:U9I401 1.7 62.4 1.0 C12 A:U9I401 2.7 62.4 1.0 C10 A:U9I401 2.7 62.4 1.0 CL1 A:U9I401 3.2 62.4 1.0 NE2 A:GLN115 3.5 71.2 1.0 CG A:GLN115 3.6 71.2 1.0 CG1 A:VAL134 3.8 63.3 1.0 CD A:GLN115 3.9 71.2 1.0 C7 A:U9I401 4.0 62.4 1.0 C9 A:U9I401 4.0 62.4 1.0 O A:PHE114 4.2 72.5 1.0 CG2 A:THR111 4.3 67.8 1.0 CB A:PHE114 4.4 72.5 1.0 CD1 A:LEU135 4.4 59.7 1.0 OD2 A:ASP138 4.5 58.2 1.0 C8 A:U9I401 4.5 62.4 1.0 C A:PHE114 4.6 72.5 1.0 CB A:GLN115 4.9 71.2 1.0 CB A:VAL134 5.0 63.3 1.0 N A:GLN115 5.0 71.2 1.0 OE1 A:GLN115 5.0 71.2 1.0 CG A:LEU135 5.0 59.7 1.0

J.Han, J.Zhang, A.L.Nazarova, S.M.Bernhard, B.E.Krumm, L.Zhao, J.H.Lam, V.A.Rangari, S.Majumdar, D.E.Nichols, V.Katritch, P.Yuan, J.F.Fay, T.Che. Ligand and G-Protein Selectivity in the Kappa-Opioid Receptor Nature 2023.
ISSN: ESSN 1476-4687
DOI: 10.1038/S41586-023-06030-7