Chlorine in PDB 8e6m: X-Ray Structure of the Deinococcus Radiodurans Nramp/Mnth Divalent Transition Metal Transporter Wt in An Inward-Open, Cadmium-Bound State

The structure of X-Ray Structure of the Deinococcus Radiodurans Nramp/Mnth Divalent Transition Metal Transporter Wt in An Inward-Open, Cadmium-Bound State, PDB code: 8e6m was solved by S.Ray, R.Gaudet, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	45.54 / 2.48
Space group	P 2 21 21
Cell size a, b, c (Å), α, β, γ (°)	59.137, 71.369, 99.054, 90, 90, 90
R / Rfree (%)	20.3 / 25

The structure of X-Ray Structure of the Deinococcus Radiodurans Nramp/Mnth Divalent Transition Metal Transporter Wt in An Inward-Open, Cadmium-Bound State also contains other interesting chemical elements:

Cadmium

(Cd)

2 atoms

The binding sites of Chlorine atom in the X-Ray Structure of the Deinococcus Radiodurans Nramp/Mnth Divalent Transition Metal Transporter Wt in An Inward-Open, Cadmium-Bound State (pdb code 8e6m). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the X-Ray Structure of the Deinococcus Radiodurans Nramp/Mnth Divalent Transition Metal Transporter Wt in An Inward-Open, Cadmium-Bound State, PDB code: 8e6m:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the X-Ray Structure of the Deinococcus Radiodurans Nramp/Mnth Divalent Transition Metal Transporter Wt in An Inward-Open, Cadmium-Bound State


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of X-Ray Structure of the Deinococcus Radiodurans Nramp/Mnth Divalent Transition Metal Transporter Wt in An Inward-Open, Cadmium-Bound State within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl503 b:70.1 occ:1.00 O A:HOH635 3.6 37.5 1.0 CB A:ALA203 4.0 38.6 1.0 O A:HOH654 4.0 76.5 1.0 CD2 A:HIS287 4.8 48.0 1.0 NE2 A:HIS287 4.8 51.6 1.0

Chlorine binding site 2 out of 2 in the X-Ray Structure of the Deinococcus Radiodurans Nramp/Mnth Divalent Transition Metal Transporter Wt in An Inward-Open, Cadmium-Bound State


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of X-Ray Structure of the Deinococcus Radiodurans Nramp/Mnth Divalent Transition Metal Transporter Wt in An Inward-Open, Cadmium-Bound State within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl504 b:63.7 occ:1.00 O A:HOH652 2.6 51.6 1.0 O A:HOH640 2.7 52.4 1.0 CE1 A:PHE395 3.3 47.0 1.0 NE A:ARG110 3.4 45.3 1.0 NH2 A:ARG110 3.5 43.4 1.0 NE1 A:TRP111 3.6 40.9 1.0 NE A:ARG398 3.9 44.4 1.0 CD A:ARG398 3.9 45.6 1.0 CZ A:ARG110 3.9 49.2 1.0 CD1 A:PHE395 3.9 49.2 1.0 CZ A:ARG398 4.0 55.4 1.0 NH1 A:ARG398 4.1 49.4 1.0 CD1 A:TRP111 4.2 41.1 1.0 CZ A:PHE395 4.4 38.9 1.0 O A:HOH628 4.4 41.1 1.0 CB A:ARG110 4.5 46.7 1.0 O23 A:OLC508 4.5 72.2 1.0 CD A:ARG110 4.5 51.9 1.0 NH2 A:ARG398 4.6 45.3 1.0 CE2 A:TRP111 4.8 41.7 1.0 O A:HOH633 4.9 55.9 1.0 C24 A:OLC508 5.0 72.8 1.0

S.Ray, S.P.Berry, E.A.Wilson, C.H.Zhang, M.Shekhar, A.Singharoy, R.Gaudet. High-Resolution Structures with Bound Mn 2+ and Cd 2+ Map the Metal Import Pathway in An Nramp Transporter. Elife V. 12 2023.
ISSN: ESSN 2050-084X
PubMed: 37039477
DOI: 10.7554/ELIFE.84006