Chlorine in PDB 8e9y: Cryoem Structure of Minigq-Coupled HM3DQ in Complex with Cno

The binding sites of Chlorine atom in the Cryoem Structure of Minigq-Coupled HM3DQ in Complex with Cno (pdb code 8e9y). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Cryoem Structure of Minigq-Coupled HM3DQ in Complex with Cno, PDB code: 8e9y:

Chlorine binding site 1 out of 1 in the Cryoem Structure of Minigq-Coupled HM3DQ in Complex with Cno


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Cryoem Structure of Minigq-Coupled HM3DQ in Complex with Cno within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl801 b:69.9 occ:1.00 CL01 A:WE9801 0.0 69.9 1.0 C02 A:WE9801 1.8 44.7 1.0 C05 A:WE9801 2.7 41.7 1.0 C03 A:WE9801 2.8 47.4 1.0 OG1 A:THR232 3.1 64.9 1.0 CG1 A:VAL511 3.7 43.4 1.0 CD1 A:LEU226 3.8 63.2 1.0 CB A:THR232 3.8 63.2 1.0 CG2 A:THR235 4.0 54.8 1.0 C06 A:WE9801 4.1 43.7 1.0 CA A:THR232 4.1 58.9 1.0 C04 A:WE9801 4.1 53.3 1.0 CG A:LEU226 4.5 66.7 1.0 O A:THR232 4.5 66.4 1.0 CH2 A:TRP200 4.5 59.8 1.0 C07 A:WE9801 4.6 52.3 1.0 C A:THR232 4.8 63.1 1.0 O A:PHE225 4.8 62.7 1.0 CZ3 A:TRP200 4.9 62.6 1.0 CA A:LEU226 4.9 67.5 1.0

S.Zhang, R.H.Gumpper, X.P.Huang, Y.Liu, B.E.Krumm, C.Cao, J.F.Fay, B.L.Roth. Molecular Basis For Selective Activation of Dreadd-Based Chemogenetics. Nature V. 612 354 2022.
ISSN: ESSN 1476-4687
PubMed: 36450989
DOI: 10.1038/S41586-022-05489-0