Chlorine in PDB 8efl: SR17018-Bound Mu-Opioid Receptor-Gi Complex

The binding sites of Chlorine atom in the SR17018-Bound Mu-Opioid Receptor-Gi Complex (pdb code 8efl). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 6 binding sites of Chlorine where determined in the SR17018-Bound Mu-Opioid Receptor-Gi Complex, PDB code: 8efl:
Jump to Chlorine binding site number: 1; 2; 3; 4; 5; 6;

Chlorine binding site 1 out of 6 in the SR17018-Bound Mu-Opioid Receptor-Gi Complex


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of SR17018-Bound Mu-Opioid Receptor-Gi Complex within 5.0Å range: probe atom residue distance (Å) B Occ R:Cl401 b:35.5 occ:1.00 CL1 R:WH9401 0.0 35.5 1.0 C19 R:WH9401 1.7 35.5 1.0 C17 R:WH9401 2.7 35.5 1.0 C16 R:WH9401 2.7 35.5 1.0 CD2 R:HIS299 3.7 11.6 1.0 CG2 R:VAL302 3.8 7.5 1.0 CG1 R:ILE298 3.9 12.1 1.0 NE2 R:HIS299 3.9 11.6 1.0 O R:ILE298 4.0 12.1 1.0 C14 R:WH9401 4.0 35.5 1.0 C15 R:WH9401 4.0 35.5 1.0 CG R:HIS299 4.0 11.6 1.0 CA R:HIS299 4.0 11.6 1.0 C R:ILE298 4.1 12.1 1.0 N R:HIS299 4.2 11.6 1.0 CE1 R:HIS299 4.3 11.6 1.0 CB R:VAL302 4.3 7.5 1.0 ND1 R:HIS299 4.3 11.6 1.0 CG2 R:ILE298 4.5 12.1 1.0 C18 R:WH9401 4.5 35.5 1.0 CB R:ILE298 4.6 12.1 1.0 CB R:HIS299 4.6 11.6 1.0 CG1 R:VAL302 4.7 7.5 1.0 CD1 R:ILE298 4.9 12.1 1.0 CA R:ILE298 5.0 12.1 1.0

Chlorine binding site 2 out of 6 in the SR17018-Bound Mu-Opioid Receptor-Gi Complex


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of SR17018-Bound Mu-Opioid Receptor-Gi Complex within 5.0Å range: probe atom residue distance (Å) B Occ R:Cl401 b:35.5 occ:1.00 CL2 R:WH9401 0.0 35.5 1.0 C04 R:WH9401 1.7 35.5 1.0 C02 R:WH9401 2.7 35.5 1.0 C06 R:WH9401 2.7 35.5 1.0 CL3 R:WH9401 3.1 35.5 1.0 CG1 R:VAL145 3.5 16.9 1.0 CG R:GLN126 3.5 22.3 1.0 NE2 R:GLN126 3.8 22.3 1.0 C01 R:WH9401 4.0 35.5 1.0 C05 R:WH9401 4.0 35.5 1.0 CD R:GLN126 4.2 22.3 1.0 CG1 R:ILE146 4.4 16.5 1.0 O R:THR122 4.4 12.7 1.0 C03 R:WH9401 4.5 35.5 1.0 CB R:VAL145 4.5 16.9 1.0 OD2 R:ASP149 4.7 15.1 1.0 CB R:GLN126 4.7 22.3 1.0 N R:GLN126 4.8 22.3 1.0 C R:VAL145 4.8 16.9 1.0 N R:ILE146 4.8 16.5 1.0 CA R:GLN126 4.9 22.3 1.0 O R:VAL145 4.9 16.9 1.0 CA R:ILE146 5.0 16.5 1.0

Chlorine binding site 3 out of 6 in the SR17018-Bound Mu-Opioid Receptor-Gi Complex


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of SR17018-Bound Mu-Opioid Receptor-Gi Complex within 5.0Å range: probe atom residue distance (Å) B Occ R:Cl401 b:35.5 occ:1.00 CL3 R:WH9401 0.0 35.5 1.0 C02 R:WH9401 1.7 35.5 1.0 C04 R:WH9401 2.7 35.5 1.0 C01 R:WH9401 2.7 35.5 1.0 CL2 R:WH9401 3.1 35.5 1.0 ND2 R:ASN129 3.1 26.2 1.0 CZ3 R:TRP135 3.5 28.9 1.0 SG R:CYS219 3.6 30.3 1.0 CB R:CYS219 3.8 30.3 1.0 CE3 R:TRP135 3.9 28.9 1.0 CH2 R:TRP135 3.9 28.9 1.0 C03 R:WH9401 4.0 35.5 1.0 C06 R:WH9401 4.0 35.5 1.0 CG R:ASN129 4.2 26.2 1.0 O R:CYS219 4.3 30.3 1.0 CB R:ASN129 4.4 26.2 1.0 C05 R:WH9401 4.5 35.5 1.0 CD2 R:TRP135 4.7 28.9 1.0 CZ2 R:TRP135 4.7 28.9 1.0 CG R:GLN126 4.8 22.3 1.0 CA R:GLN126 4.9 22.3 1.0 O R:PHE125 5.0 22.2 1.0

Chlorine binding site 4 out of 6 in the SR17018-Bound Mu-Opioid Receptor-Gi Complex


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of SR17018-Bound Mu-Opioid Receptor-Gi Complex within 5.0Å range: probe atom residue distance (Å) B Occ M:Cl401 b:39.8 occ:1.00 CL1 M:WH9401 0.0 39.8 1.0 C19 M:WH9401 1.7 39.8 1.0 C17 M:WH9401 2.7 39.8 1.0 C16 M:WH9401 2.7 39.8 1.0 CD2 M:HIS299 3.6 11.4 1.0 NE2 M:HIS299 3.8 11.4 1.0 C14 M:WH9401 4.0 39.8 1.0 C15 M:WH9401 4.0 39.8 1.0 CG2 M:VAL302 4.1 11.7 1.0 CG M:HIS299 4.1 11.4 1.0 CB M:VAL302 4.3 11.7 1.0 CA M:HIS299 4.3 11.4 1.0 CE1 M:HIS299 4.4 11.4 1.0 CG1 M:VAL302 4.5 11.7 1.0 O M:ILE298 4.5 12.4 1.0 C18 M:WH9401 4.5 39.8 1.0 ND1 M:HIS299 4.5 11.4 1.0 CG1 M:ILE298 4.6 12.4 1.0 N M:HIS299 4.7 11.4 1.0 CG1 M:VAL238 4.7 25.6 1.0 C M:ILE298 4.7 12.4 1.0 CB M:HIS299 4.8 11.4 1.0

Chlorine binding site 5 out of 6 in the SR17018-Bound Mu-Opioid Receptor-Gi Complex


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 5 of SR17018-Bound Mu-Opioid Receptor-Gi Complex within 5.0Å range: probe atom residue distance (Å) B Occ M:Cl401 b:39.8 occ:1.00 CL2 M:WH9401 0.0 39.8 1.0 C04 M:WH9401 1.7 39.8 1.0 C02 M:WH9401 2.7 39.8 1.0 C06 M:WH9401 2.7 39.8 1.0 CL3 M:WH9401 3.1 39.8 1.0 CG M:GLN126 3.5 27.3 1.0 CG1 M:VAL145 3.5 20.0 1.0 C01 M:WH9401 4.0 39.8 1.0 NE2 M:GLN126 4.0 27.3 1.0 C05 M:WH9401 4.0 39.8 1.0 O M:THR122 4.1 19.9 1.0 CD M:GLN126 4.3 27.3 1.0 N M:GLN126 4.4 27.3 1.0 C03 M:WH9401 4.5 39.8 1.0 CB M:PHE125 4.5 27.9 1.0 CB M:GLN126 4.7 27.3 1.0 OD2 M:ASP149 4.7 16.9 1.0 CA M:GLN126 4.7 27.3 1.0 CB M:VAL145 4.8 20.0 1.0 CB M:THR122 4.8 19.9 1.0 C M:PHE125 4.9 27.9 1.0

Chlorine binding site 6 out of 6 in the SR17018-Bound Mu-Opioid Receptor-Gi Complex


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 6 of SR17018-Bound Mu-Opioid Receptor-Gi Complex within 5.0Å range: probe atom residue distance (Å) B Occ M:Cl401 b:39.8 occ:1.00 CL3 M:WH9401 0.0 39.8 1.0 C02 M:WH9401 1.7 39.8 1.0 C01 M:WH9401 2.7 39.8 1.0 C04 M:WH9401 2.7 39.8 1.0 CL2 M:WH9401 3.1 39.8 1.0 ND2 M:ASN129 3.4 33.3 1.0 CZ3 M:TRP135 3.4 36.4 1.0 CE3 M:TRP135 3.7 36.4 1.0 SG M:CYS219 3.8 37.2 1.0 C03 M:WH9401 4.0 39.8 1.0 C06 M:WH9401 4.0 39.8 1.0 CB M:CYS219 4.0 37.2 1.0 CH2 M:TRP135 4.1 36.4 1.0 CG M:ASN129 4.3 33.3 1.0 CB M:ASN129 4.4 33.3 1.0 C05 M:WH9401 4.5 39.8 1.0 O M:CYS219 4.5 37.2 1.0 CD2 M:TRP135 4.7 36.4 1.0 O M:PHE125 4.7 27.9 1.0 C M:PHE125 5.0 27.9 1.0 CZ2 M:TRP135 5.0 36.4 1.0

Y.Zhuang, Y.Wang, B.He, X.He, X.E.Zhou, S.Guo, Q.Rao, J.Yang, J.Liu, Q.Zhou, X.Wang, M.Liu, W.Liu, X.Jiang, D.Yang, H.Jiang, J.Shen, K.Melcher, H.Chen, Y.Jiang, X.Cheng, M.W.Wang, X.Xie, H.E.Xu. Molecular Recognition of Morphine and Fentanyl By the Human Mu-Opioid Receptor. Cell V. 185 4361 2022.
ISSN: ISSN 1097-4172
PubMed: 36368306
DOI: 10.1016/J.CELL.2022.09.041