Chlorine in PDB 8f1z: Egfr Kinase in Complex with Bayer #33

All present enzymatic activity of Egfr Kinase in Complex with Bayer #33:
2.7.10.1;

The structure of Egfr Kinase in Complex with Bayer #33, PDB code: 8f1z was solved by T.S.Beyett, M.J.Eck, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	59.66 / 2.40
Space group	I 2 3
Cell size a, b, c (Å), α, β, γ (°)	146.131, 146.131, 146.131, 90, 90, 90
R / Rfree (%)	19.2 / 21.2

The binding sites of Chlorine atom in the Egfr Kinase in Complex with Bayer #33 (pdb code 8f1z). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Egfr Kinase in Complex with Bayer #33, PDB code: 8f1z:

Chlorine binding site 1 out of 1 in the Egfr Kinase in Complex with Bayer #33


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Egfr Kinase in Complex with Bayer #33 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1101 b:57.8 occ:1.00 CL01 A:X9B1101 0.0 57.8 1.0 C02 A:X9B1101 1.7 57.0 1.0 C07 A:X9B1101 2.6 56.3 1.0 C03 A:X9B1101 2.8 51.3 1.0 O32 A:X9B1101 3.1 55.8 1.0 CB A:LEU788 3.4 57.4 1.0 SD A:MET766 3.6 65.8 1.0 CD1 A:LEU777 3.7 50.0 1.0 CB A:THR790 3.7 49.3 1.0 CE A:MET766 3.7 54.5 1.0 C33 A:X9B1101 3.8 53.7 1.0 CD1 A:LEU788 3.8 61.4 1.0 C06 A:X9B1101 3.9 48.7 1.0 C04 A:X9B1101 4.1 61.0 1.0 CG A:LEU788 4.2 70.0 1.0 CG2 A:THR790 4.2 45.7 1.0 O A:ILE789 4.3 53.5 1.0 C A:LEU788 4.3 61.5 1.0 C A:ILE789 4.3 60.2 1.0 N A:ILE789 4.3 58.0 1.0 OG1 A:THR790 4.3 47.1 1.0 CA A:LEU788 4.4 51.2 1.0 N A:THR790 4.5 55.0 1.0 C05 A:X9B1101 4.5 52.3 1.0 CA A:THR790 4.6 46.9 1.0 O A:LEU788 4.7 58.1 1.0 CA A:ILE789 4.9 60.9 1.0 CG A:LEU777 5.0 57.7 1.0 CA A:LEU777 5.0 50.8 1.0

T.S.Beyett, M.J.Eck. Egfr Kinase in Complex with Bayer #33 To Be Published.