Chlorine in PDB 8fcb: Cryo-Em Structure of the Human TRPV4 - Rhoa in Complex with GSK1016790A

Enzymatic activity of Cryo-Em Structure of the Human TRPV4 - Rhoa in Complex with GSK1016790A

All present enzymatic activity of Cryo-Em Structure of the Human TRPV4 - Rhoa in Complex with GSK1016790A:
3.6.5.2;

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Cryo-Em Structure of the Human TRPV4 - Rhoa in Complex with GSK1016790A (pdb code 8fcb). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 8 binding sites of Chlorine where determined in the Cryo-Em Structure of the Human TRPV4 - Rhoa in Complex with GSK1016790A, PDB code: 8fcb:
Jump to Chlorine binding site number: 1; 2; 3; 4; 5; 6; 7; 8;

Chlorine binding site 1 out of 8 in 8fcb

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Chlorine binding site 1 out of 8 in the Cryo-Em Structure of the Human TRPV4 - Rhoa in Complex with GSK1016790A


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Cryo-Em Structure of the Human TRPV4 - Rhoa in Complex with GSK1016790A within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl901

b:68.4
occ:1.00
 CL34 A:XQ3901 0.0 68.4 1.0
C33 A:XQ3901 1.8 68.4 1.0
C35 A:XQ3901 2.8 68.4 1.0
C32 A:XQ3901 2.8 68.4 1.0
H351 A:XQ3901 2.8 68.4 1.0
HG22 A:THR527 2.9 81.7 1.0
O40 A:XQ3901 3.0 68.4 1.0
O41 A:XQ3901 3.0 68.4 1.0
HD1 A:PHE524 3.1 75.0 1.0
S30 A:XQ3901 3.2 68.4 1.0
HB A:THR527 3.3 81.7 1.0
HG21 A:THR527 3.5 81.7 1.0
CG2 A:THR527 3.6 81.7 1.0
CD1 A:PHE524 3.6 75.0 1.0
N29 A:XQ3901 3.7 68.4 1.0
OD1 A:ASN528 3.7 83.6 1.0
HA A:PHE524 3.8 75.0 1.0
C25 A:XQ3901 3.8 68.4 1.0
O A:PHE524 3.9 75.0 1.0
H291 A:XQ3901 4.0 68.4 1.0
CB A:THR527 4.0 81.7 1.0
HB2 A:ASN528 4.0 83.6 1.0
HE1 A:PHE524 4.0 75.0 1.0
C36 A:XQ3901 4.0 68.4 1.0
C39 A:XQ3901 4.1 68.4 1.0
CE1 A:PHE524 4.2 75.0 1.0
HB3 A:TYR553 4.2 73.5 1.0
CG A:ASN528 4.2 83.6 1.0
C26 A:XQ3901 4.3 68.4 1.0
HB2 A:TYR553 4.3 73.5 1.0
N A:ASN528 4.4 83.6 1.0
HG23 A:THR527 4.4 81.7 1.0
HB3 A:PHE524 4.4 75.0 1.0
H A:ASN528 4.5 83.6 1.0
HA A:ASN528 4.5 83.6 1.0
CB A:ASN528 4.5 83.6 1.0
CG A:PHE524 4.5 75.0 1.0
CA A:PHE524 4.5 75.0 1.0
H212 A:XQ3901 4.6 68.4 1.0
C38 A:XQ3901 4.6 68.4 1.0
O31 A:XQ3901 4.6 68.4 1.0
C A:PHE524 4.6 75.0 1.0
H261 A:XQ3901 4.6 68.4 1.0
CB A:TYR553 4.6 73.5 1.0
C A:THR527 4.7 81.7 1.0
CB A:PHE524 4.7 75.0 1.0
CA A:ASN528 4.7 83.6 1.0
H391 A:XQ3901 4.8 68.4 1.0
N22 A:XQ3901 4.8 68.4 1.0
CG A:TYR553 4.9 73.5 1.0
HD2 A:TYR553 4.9 73.5 1.0
CA A:THR527 5.0 81.7 1.0
H201 A:XQ3901 5.0 68.4 1.0
OG1 A:THR527 5.0 81.7 1.0
ND2 A:ASN528 5.0 83.6 1.0

Chlorine binding site 2 out of 8 in 8fcb

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Chlorine binding site 2 out of 8 in the Cryo-Em Structure of the Human TRPV4 - Rhoa in Complex with GSK1016790A


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Cryo-Em Structure of the Human TRPV4 - Rhoa in Complex with GSK1016790A within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl901

b:68.4
occ:1.00
 CL37 A:XQ3901 0.0 68.4 1.0
C36 A:XQ3901 1.8 68.4 1.0
C35 A:XQ3901 2.7 68.4 1.0
C38 A:XQ3901 2.8 68.4 1.0
H351 A:XQ3901 2.8 68.4 1.0
H381 A:XQ3901 2.9 68.4 1.0
HZ A:PHE592 3.0 71.4 1.0
H091 A:XQ3901 3.1 68.4 1.0
C09 A:XQ3901 3.2 68.4 1.0
HZ A:PHE524 3.3 75.0 1.0
H201 A:XQ3901 3.5 68.4 1.0
C10 A:XQ3901 3.6 68.4 1.0
CZ A:PHE524 3.7 75.0 1.0
OD1 A:ASN474 3.7 68.0 1.0
C08 A:XQ3901 3.8 68.4 1.0
HE1 A:PHE524 3.8 75.0 1.0
H111 A:XQ3901 3.9 68.4 1.0
CZ A:PHE592 3.9 71.4 1.0
C11 A:XQ3901 3.9 68.4 1.0
CE1 A:PHE524 4.0 75.0 1.0
C33 A:XQ3901 4.0 68.4 1.0
C39 A:XQ3901 4.1 68.4 1.0
HE1 A:PHE592 4.3 71.4 1.0
H061 A:XQ3901 4.3 68.4 1.0
C15 A:XQ3901 4.3 68.4 1.0
C07 A:XQ3901 4.4 68.4 1.0
C20 A:XQ3901 4.4 68.4 1.0
HD21 A:ASN474 4.4 68.0 1.0
CE2 A:PHE524 4.5 75.0 1.0
N06 A:XQ3901 4.5 68.4 1.0
HD1 A:TYR478 4.5 66.2 1.0
C32 A:XQ3901 4.6 68.4 1.0
CE1 A:PHE592 4.6 71.4 1.0
S16 A:XQ3901 4.6 68.4 1.0
HB2 A:TYR478 4.6 66.2 1.0
H202 A:XQ3901 4.6 68.4 1.0
CG A:ASN474 4.6 68.0 1.0
H241 A:XQ3901 4.6 68.4 1.0
HE2 A:PHE524 4.7 75.0 1.0
HE2 A:TYR591 4.8 77.3 1.0
H391 A:XQ3901 4.8 68.4 1.0
N19 A:XQ3901 4.8 68.4 1.0
ND2 A:ASN474 4.9 68.0 1.0
HE2 A:PHE592 4.9 71.4 1.0
C12 A:XQ3901 4.9 68.4 1.0
CE2 A:PHE592 4.9 71.4 1.0
CD1 A:PHE524 5.0 75.0 1.0

Chlorine binding site 3 out of 8 in 8fcb

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Chlorine binding site 3 out of 8 in the Cryo-Em Structure of the Human TRPV4 - Rhoa in Complex with GSK1016790A


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Cryo-Em Structure of the Human TRPV4 - Rhoa in Complex with GSK1016790A within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl901

b:68.4
occ:1.00
 CL34 B:XQ3901 0.0 68.4 1.0
C33 B:XQ3901 1.8 68.4 1.0
C35 B:XQ3901 2.7 68.4 1.0
C32 B:XQ3901 2.8 68.4 1.0
H351 B:XQ3901 2.8 68.4 1.0
HG22 B:THR527 2.9 81.7 1.0
O40 B:XQ3901 3.0 68.4 1.0
O41 B:XQ3901 3.0 68.4 1.0
HD1 B:PHE524 3.1 75.0 1.0
S30 B:XQ3901 3.2 68.4 1.0
HB B:THR527 3.3 81.7 1.0
HG21 B:THR527 3.5 81.7 1.0
CG2 B:THR527 3.6 81.7 1.0
CD1 B:PHE524 3.6 75.0 1.0
N29 B:XQ3901 3.7 68.4 1.0
OD1 B:ASN528 3.7 83.6 1.0
HA B:PHE524 3.8 75.0 1.0
C25 B:XQ3901 3.8 68.4 1.0
O B:PHE524 3.9 75.0 1.0
H291 B:XQ3901 4.0 68.4 1.0
CB B:THR527 4.0 81.7 1.0
HB2 B:ASN528 4.0 83.6 1.0
HE1 B:PHE524 4.0 75.0 1.0
C36 B:XQ3901 4.0 68.4 1.0
C39 B:XQ3901 4.1 68.4 1.0
CE1 B:PHE524 4.2 75.0 1.0
HB3 B:TYR553 4.2 73.5 1.0
CG B:ASN528 4.2 83.6 1.0
C26 B:XQ3901 4.3 68.4 1.0
HB2 B:TYR553 4.3 73.5 1.0
N B:ASN528 4.4 83.6 1.0
HG23 B:THR527 4.4 81.7 1.0
HB3 B:PHE524 4.4 75.0 1.0
H B:ASN528 4.5 83.6 1.0
HA B:ASN528 4.5 83.6 1.0
CB B:ASN528 4.5 83.6 1.0
CG B:PHE524 4.5 75.0 1.0
CA B:PHE524 4.5 75.0 1.0
H212 B:XQ3901 4.6 68.4 1.0
C38 B:XQ3901 4.6 68.4 1.0
O31 B:XQ3901 4.6 68.4 1.0
C B:PHE524 4.6 75.0 1.0
H261 B:XQ3901 4.6 68.4 1.0
CB B:TYR553 4.6 73.5 1.0
C B:THR527 4.7 81.7 1.0
CB B:PHE524 4.7 75.0 1.0
CA B:ASN528 4.7 83.6 1.0
H391 B:XQ3901 4.8 68.4 1.0
N22 B:XQ3901 4.8 68.4 1.0
CG B:TYR553 4.9 73.5 1.0
HD2 B:TYR553 4.9 73.5 1.0
CA B:THR527 5.0 81.7 1.0
H201 B:XQ3901 5.0 68.4 1.0
OG1 B:THR527 5.0 81.7 1.0
ND2 B:ASN528 5.0 83.6 1.0

Chlorine binding site 4 out of 8 in 8fcb

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Chlorine binding site 4 out of 8 in the Cryo-Em Structure of the Human TRPV4 - Rhoa in Complex with GSK1016790A


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Cryo-Em Structure of the Human TRPV4 - Rhoa in Complex with GSK1016790A within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl901

b:68.4
occ:1.00
 CL37 B:XQ3901 0.0 68.4 1.0
C36 B:XQ3901 1.8 68.4 1.0
C35 B:XQ3901 2.7 68.4 1.0
C38 B:XQ3901 2.8 68.4 1.0
H351 B:XQ3901 2.8 68.4 1.0
H381 B:XQ3901 2.9 68.4 1.0
HZ B:PHE592 3.0 71.4 1.0
H091 B:XQ3901 3.1 68.4 1.0
C09 B:XQ3901 3.2 68.4 1.0
HZ B:PHE524 3.3 75.0 1.0
H201 B:XQ3901 3.5 68.4 1.0
C10 B:XQ3901 3.6 68.4 1.0
CZ B:PHE524 3.7 75.0 1.0
OD1 B:ASN474 3.7 68.0 1.0
C08 B:XQ3901 3.8 68.4 1.0
HE1 B:PHE524 3.8 75.0 1.0
H111 B:XQ3901 3.9 68.4 1.0
CZ B:PHE592 3.9 71.4 1.0
C11 B:XQ3901 3.9 68.4 1.0
CE1 B:PHE524 4.0 75.0 1.0
C33 B:XQ3901 4.0 68.4 1.0
C39 B:XQ3901 4.1 68.4 1.0
HE1 B:PHE592 4.3 71.4 1.0
H061 B:XQ3901 4.3 68.4 1.0
C15 B:XQ3901 4.3 68.4 1.0
C07 B:XQ3901 4.4 68.4 1.0
C20 B:XQ3901 4.4 68.4 1.0
HD21 B:ASN474 4.4 68.0 1.0
CE2 B:PHE524 4.5 75.0 1.0
N06 B:XQ3901 4.5 68.4 1.0
HD1 B:TYR478 4.5 66.2 1.0
C32 B:XQ3901 4.6 68.4 1.0
CE1 B:PHE592 4.6 71.4 1.0
S16 B:XQ3901 4.6 68.4 1.0
HB2 B:TYR478 4.6 66.2 1.0
H202 B:XQ3901 4.6 68.4 1.0
CG B:ASN474 4.6 68.0 1.0
H241 B:XQ3901 4.6 68.4 1.0
HE2 B:PHE524 4.7 75.0 1.0
HE2 B:TYR591 4.8 77.3 1.0
H391 B:XQ3901 4.8 68.4 1.0
N19 B:XQ3901 4.8 68.4 1.0
ND2 B:ASN474 4.9 68.0 1.0
HE2 B:PHE592 4.9 71.4 1.0
C12 B:XQ3901 4.9 68.4 1.0
CE2 B:PHE592 4.9 71.4 1.0
CD1 B:PHE524 5.0 75.0 1.0

Chlorine binding site 5 out of 8 in 8fcb

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Chlorine binding site 5 out of 8 in the Cryo-Em Structure of the Human TRPV4 - Rhoa in Complex with GSK1016790A


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 5 of Cryo-Em Structure of the Human TRPV4 - Rhoa in Complex with GSK1016790A within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Cl1002

b:68.4
occ:1.00
 CL34 C:XQ31002 0.0 68.4 1.0
C33 C:XQ31002 1.8 68.4 1.0
C35 C:XQ31002 2.8 68.4 1.0
C32 C:XQ31002 2.8 68.4 1.0
H351 C:XQ31002 2.8 68.4 1.0
HG22 C:THR527 2.9 81.7 1.0
O40 C:XQ31002 3.0 68.4 1.0
O41 C:XQ31002 3.0 68.4 1.0
HD1 C:PHE524 3.1 75.0 1.0
S30 C:XQ31002 3.2 68.4 1.0
HB C:THR527 3.3 81.7 1.0
HG21 C:THR527 3.5 81.7 1.0
CG2 C:THR527 3.6 81.7 1.0
CD1 C:PHE524 3.6 75.0 1.0
N29 C:XQ31002 3.7 68.4 1.0
OD1 C:ASN528 3.7 83.6 1.0
HA C:PHE524 3.8 75.0 1.0
C25 C:XQ31002 3.8 68.4 1.0
O C:PHE524 3.9 75.0 1.0
H291 C:XQ31002 4.0 68.4 1.0
CB C:THR527 4.0 81.7 1.0
HB2 C:ASN528 4.0 83.6 1.0
HE1 C:PHE524 4.0 75.0 1.0
C36 C:XQ31002 4.0 68.4 1.0
C39 C:XQ31002 4.1 68.4 1.0
CE1 C:PHE524 4.2 75.0 1.0
HB3 C:TYR553 4.2 73.5 1.0
CG C:ASN528 4.2 83.6 1.0
C26 C:XQ31002 4.3 68.4 1.0
HB2 C:TYR553 4.3 73.5 1.0
N C:ASN528 4.4 83.6 1.0
HG23 C:THR527 4.4 81.7 1.0
HB3 C:PHE524 4.4 75.0 1.0
H C:ASN528 4.5 83.6 1.0
HA C:ASN528 4.5 83.6 1.0
CB C:ASN528 4.5 83.6 1.0
CG C:PHE524 4.5 75.0 1.0
CA C:PHE524 4.5 75.0 1.0
H212 C:XQ31002 4.6 68.4 1.0
C38 C:XQ31002 4.6 68.4 1.0
O31 C:XQ31002 4.6 68.4 1.0
C C:PHE524 4.6 75.0 1.0
H261 C:XQ31002 4.6 68.4 1.0
CB C:TYR553 4.6 73.5 1.0
C C:THR527 4.7 81.7 1.0
CB C:PHE524 4.7 75.0 1.0
CA C:ASN528 4.7 83.6 1.0
H391 C:XQ31002 4.8 68.4 1.0
N22 C:XQ31002 4.8 68.4 1.0
CG C:TYR553 4.9 73.5 1.0
HD2 C:TYR553 4.9 73.5 1.0
CA C:THR527 5.0 81.7 1.0
H201 C:XQ31002 5.0 68.4 1.0
OG1 C:THR527 5.0 81.7 1.0
ND2 C:ASN528 5.0 83.6 1.0

Chlorine binding site 6 out of 8 in 8fcb

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Chlorine binding site 6 out of 8 in the Cryo-Em Structure of the Human TRPV4 - Rhoa in Complex with GSK1016790A


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 6 of Cryo-Em Structure of the Human TRPV4 - Rhoa in Complex with GSK1016790A within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Cl1002

b:68.4
occ:1.00
 CL37 C:XQ31002 0.0 68.4 1.0
C36 C:XQ31002 1.8 68.4 1.0
C35 C:XQ31002 2.7 68.4 1.0
C38 C:XQ31002 2.8 68.4 1.0
H351 C:XQ31002 2.8 68.4 1.0
H381 C:XQ31002 2.9 68.4 1.0
HZ C:PHE592 3.0 71.4 1.0
H091 C:XQ31002 3.1 68.4 1.0
C09 C:XQ31002 3.2 68.4 1.0
HZ C:PHE524 3.3 75.0 1.0
H201 C:XQ31002 3.5 68.4 1.0
C10 C:XQ31002 3.6 68.4 1.0
CZ C:PHE524 3.7 75.0 1.0
OD1 C:ASN474 3.7 68.0 1.0
C08 C:XQ31002 3.8 68.4 1.0
HE1 C:PHE524 3.8 75.0 1.0
H111 C:XQ31002 3.9 68.4 1.0
CZ C:PHE592 3.9 71.4 1.0
C11 C:XQ31002 3.9 68.4 1.0
CE1 C:PHE524 4.0 75.0 1.0
C33 C:XQ31002 4.0 68.4 1.0
C39 C:XQ31002 4.1 68.4 1.0
HE1 C:PHE592 4.3 71.4 1.0
H061 C:XQ31002 4.3 68.4 1.0
C15 C:XQ31002 4.3 68.4 1.0
C07 C:XQ31002 4.4 68.4 1.0
C20 C:XQ31002 4.4 68.4 1.0
HD21 C:ASN474 4.4 68.0 1.0
CE2 C:PHE524 4.5 75.0 1.0
N06 C:XQ31002 4.5 68.4 1.0
HD1 C:TYR478 4.5 66.2 1.0
C32 C:XQ31002 4.6 68.4 1.0
CE1 C:PHE592 4.6 71.4 1.0
S16 C:XQ31002 4.6 68.4 1.0
HB2 C:TYR478 4.6 66.2 1.0
H202 C:XQ31002 4.6 68.4 1.0
CG C:ASN474 4.6 68.0 1.0
H241 C:XQ31002 4.6 68.4 1.0
HE2 C:PHE524 4.7 75.0 1.0
HE2 C:TYR591 4.8 77.3 1.0
H391 C:XQ31002 4.8 68.4 1.0
N19 C:XQ31002 4.8 68.4 1.0
ND2 C:ASN474 4.9 68.0 1.0
HE2 C:PHE592 4.9 71.4 1.0
C12 C:XQ31002 4.9 68.4 1.0
CE2 C:PHE592 4.9 71.4 1.0
CD1 C:PHE524 5.0 75.0 1.0

Chlorine binding site 7 out of 8 in 8fcb

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Chlorine binding site 7 out of 8 in the Cryo-Em Structure of the Human TRPV4 - Rhoa in Complex with GSK1016790A


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 7 of Cryo-Em Structure of the Human TRPV4 - Rhoa in Complex with GSK1016790A within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Cl901

b:68.4
occ:1.00
 CL34 D:XQ3901 0.0 68.4 1.0
C33 D:XQ3901 1.8 68.4 1.0
C35 D:XQ3901 2.8 68.4 1.0
C32 D:XQ3901 2.8 68.4 1.0
H351 D:XQ3901 2.8 68.4 1.0
HG22 D:THR527 2.9 81.7 1.0
O40 D:XQ3901 3.0 68.4 1.0
O41 D:XQ3901 3.0 68.4 1.0
HD1 D:PHE524 3.1 75.0 1.0
S30 D:XQ3901 3.2 68.4 1.0
HB D:THR527 3.3 81.7 1.0
HG21 D:THR527 3.5 81.7 1.0
CG2 D:THR527 3.6 81.7 1.0
CD1 D:PHE524 3.6 75.0 1.0
N29 D:XQ3901 3.7 68.4 1.0
OD1 D:ASN528 3.7 83.6 1.0
HA D:PHE524 3.8 75.0 1.0
C25 D:XQ3901 3.8 68.4 1.0
O D:PHE524 3.9 75.0 1.0
H291 D:XQ3901 4.0 68.4 1.0
CB D:THR527 4.0 81.7 1.0
HB2 D:ASN528 4.0 83.6 1.0
HE1 D:PHE524 4.0 75.0 1.0
C36 D:XQ3901 4.0 68.4 1.0
C39 D:XQ3901 4.1 68.4 1.0
CE1 D:PHE524 4.2 75.0 1.0
HB3 D:TYR553 4.2 73.5 1.0
CG D:ASN528 4.2 83.6 1.0
C26 D:XQ3901 4.3 68.4 1.0
HB2 D:TYR553 4.3 73.5 1.0
N D:ASN528 4.4 83.6 1.0
HG23 D:THR527 4.4 81.7 1.0
HB3 D:PHE524 4.4 75.0 1.0
H D:ASN528 4.5 83.6 1.0
HA D:ASN528 4.5 83.6 1.0
CB D:ASN528 4.5 83.6 1.0
CG D:PHE524 4.5 75.0 1.0
CA D:PHE524 4.5 75.0 1.0
H212 D:XQ3901 4.6 68.4 1.0
C38 D:XQ3901 4.6 68.4 1.0
O31 D:XQ3901 4.6 68.4 1.0
C D:PHE524 4.6 75.0 1.0
H261 D:XQ3901 4.6 68.4 1.0
CB D:TYR553 4.6 73.5 1.0
C D:THR527 4.7 81.7 1.0
CB D:PHE524 4.7 75.0 1.0
CA D:ASN528 4.7 83.6 1.0
H391 D:XQ3901 4.8 68.4 1.0
N22 D:XQ3901 4.8 68.4 1.0
CG D:TYR553 4.9 73.5 1.0
HD2 D:TYR553 4.9 73.5 1.0
CA D:THR527 5.0 81.7 1.0
H201 D:XQ3901 5.0 68.4 1.0
OG1 D:THR527 5.0 81.7 1.0
ND2 D:ASN528 5.0 83.6 1.0

Chlorine binding site 8 out of 8 in 8fcb

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Chlorine binding site 8 out of 8 in the Cryo-Em Structure of the Human TRPV4 - Rhoa in Complex with GSK1016790A


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 8 of Cryo-Em Structure of the Human TRPV4 - Rhoa in Complex with GSK1016790A within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Cl901

b:68.4
occ:1.00
 CL37 D:XQ3901 0.0 68.4 1.0
C36 D:XQ3901 1.8 68.4 1.0
C35 D:XQ3901 2.7 68.4 1.0
C38 D:XQ3901 2.8 68.4 1.0
H351 D:XQ3901 2.8 68.4 1.0
H381 D:XQ3901 2.9 68.4 1.0
HZ D:PHE592 3.0 71.4 1.0
H091 D:XQ3901 3.1 68.4 1.0
C09 D:XQ3901 3.2 68.4 1.0
HZ D:PHE524 3.3 75.0 1.0
H201 D:XQ3901 3.5 68.4 1.0
C10 D:XQ3901 3.6 68.4 1.0
CZ D:PHE524 3.7 75.0 1.0
OD1 D:ASN474 3.7 68.0 1.0
C08 D:XQ3901 3.8 68.4 1.0
HE1 D:PHE524 3.8 75.0 1.0
H111 D:XQ3901 3.9 68.4 1.0
CZ D:PHE592 3.9 71.4 1.0
C11 D:XQ3901 3.9 68.4 1.0
CE1 D:PHE524 4.0 75.0 1.0
C33 D:XQ3901 4.0 68.4 1.0
C39 D:XQ3901 4.1 68.4 1.0
HE1 D:PHE592 4.3 71.4 1.0
H061 D:XQ3901 4.3 68.4 1.0
C15 D:XQ3901 4.3 68.4 1.0
C07 D:XQ3901 4.4 68.4 1.0
C20 D:XQ3901 4.4 68.4 1.0
HD21 D:ASN474 4.4 68.0 1.0
CE2 D:PHE524 4.5 75.0 1.0
N06 D:XQ3901 4.5 68.4 1.0
HD1 D:TYR478 4.5 66.2 1.0
C32 D:XQ3901 4.6 68.4 1.0
CE1 D:PHE592 4.6 71.4 1.0
S16 D:XQ3901 4.6 68.4 1.0
HB2 D:TYR478 4.6 66.2 1.0
H202 D:XQ3901 4.6 68.4 1.0
CG D:ASN474 4.6 68.0 1.0
H241 D:XQ3901 4.6 68.4 1.0
HE2 D:PHE524 4.7 75.0 1.0
HE2 D:TYR591 4.8 77.3 1.0
H391 D:XQ3901 4.8 68.4 1.0
N19 D:XQ3901 4.8 68.4 1.0
ND2 D:ASN474 4.9 68.0 1.0
HE2 D:PHE592 4.9 71.4 1.0
C12 D:XQ3901 4.9 68.4 1.0
CE2 D:PHE592 4.9 71.4 1.0
CD1 D:PHE524 5.0 75.0 1.0

Reference:

D.H.Kwon, F.Zhang, B.A.Mccray, S.Feng, M.Kumar, J.M.Sullivan, W.Im, C.J.Sumner, S.Y.Lee. TRPV4-Rho Gtpase Complex Structures Reveal Mechanisms of Gating and Disease. Nat Commun V. 14 3732 2023.
ISSN: ESSN 2041-1723
PubMed: 37353484
DOI: 10.1038/S41467-023-39345-0
Page generated: Tue Jul 30 09:25:24 2024

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