Chlorine in PDB 8fh8: Crystal Structure of Aldose Reductase (AKR1B1) Complexed with Nadp+ and at-003 Soaked in Hydrogen Peroxide

Enzymatic activity of Crystal Structure of Aldose Reductase (AKR1B1) Complexed with Nadp+ and at-003 Soaked in Hydrogen Peroxide

All present enzymatic activity of Crystal Structure of Aldose Reductase (AKR1B1) Complexed with Nadp+ and at-003 Soaked in Hydrogen Peroxide:
1.1.1.21; 1.1.1.300; 1.1.1.372; 1.1.1.54;

Protein crystallography data

The structure of Crystal Structure of Aldose Reductase (AKR1B1) Complexed with Nadp+ and at-003 Soaked in Hydrogen Peroxide, PDB code: 8fh8 was solved by R.Arenas, D.K.Wilson, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 36.48 / 1.60
Space group P 1
Cell size a, b, c (Å), α, β, γ (°) 40.061, 46.989, 48.237, 77.11, 66.94, 77.24
R / Rfree (%) 16.7 / 19.5

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Crystal Structure of Aldose Reductase (AKR1B1) Complexed with Nadp+ and at-003 Soaked in Hydrogen Peroxide (pdb code 8fh8). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Aldose Reductase (AKR1B1) Complexed with Nadp+ and at-003 Soaked in Hydrogen Peroxide, PDB code: 8fh8:

Chlorine binding site 1 out of 1 in 8fh8

Go back to Chlorine Binding Sites List in 8fh8
Chlorine binding site 1 out of 1 in the Crystal Structure of Aldose Reductase (AKR1B1) Complexed with Nadp+ and at-003 Soaked in Hydrogen Peroxide


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Aldose Reductase (AKR1B1) Complexed with Nadp+ and at-003 Soaked in Hydrogen Peroxide within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl402

b:32.6
occ:1.00
 CL19 A:XY0402 0.0 32.6 1.0
C15 A:XY0402 1.7 26.9 1.0
C16 A:XY0402 2.6 26.1 1.0
C14 A:XY0402 2.7 27.3 1.0
H16 A:XY0402 2.7 25.5 1.0
H14 A:XY0402 2.8 27.4 1.0
HA A:LEU300 2.8 20.9 1.0
HG A:SER302 2.9 32.3 0.0
HD13 A:LEU300 3.0 25.0 1.0
HB2 A:SER302 3.0 25.2 1.0
H A:SER302 3.1 22.6 1.0
HE1 A:PHE122 3.6 22.2 1.0
OG A:SER302 3.6 32.1 1.0
HG A:LEU300 3.7 22.6 1.0
CA A:LEU300 3.7 20.9 1.0
CD1 A:LEU300 3.7 26.2 1.0
H A:LEU301 3.7 21.6 1.0
CB A:SER302 3.7 23.3 1.0
HD11 A:LEU300 3.8 25.1 1.0
C A:LEU300 3.8 22.0 1.0
N A:SER302 3.9 21.0 1.0
C12 A:XY0402 3.9 22.7 1.0
N A:LEU301 3.9 21.0 1.0
C13 A:XY0402 4.0 28.0 1.0
CE1 A:PHE122 4.1 23.3 1.0
CG A:LEU300 4.1 22.6 1.0
O A:HOH611 4.2 29.2 1.0
O A:LEU300 4.3 23.1 1.0
CA A:SER302 4.4 23.4 1.0
C11 A:XY0402 4.4 27.3 1.0
CB A:LEU300 4.5 21.1 1.0
HB3 A:SER302 4.5 25.1 1.0
HD12 A:LEU300 4.5 25.0 1.0
HD1 A:PHE122 4.6 21.1 1.0
CD1 A:PHE122 4.7 20.5 1.0
H A:LEU300 4.7 19.9 1.0
O A:HOH606 4.7 28.0 1.0
N A:LEU300 4.7 19.1 1.0
H13 A:XY0402 4.7 27.7 1.0
SG A:CYS303 4.8 23.0 1.0
HZ A:PHE122 4.8 22.3 1.0
H A:CYS303 4.8 19.8 1.0
CZ A:PHE122 4.8 21.5 1.0
C A:LEU301 4.9 25.7 1.0
HB2 A:LEU300 5.0 21.4 1.0
HG A:CYS303 5.0 23.1 0.0
CA A:LEU301 5.0 22.7 1.0

Reference:

R.Arenas, D.K.Wilson. Crystal Structure of Aldose Reductase (AKR1B1) Complexed with Nadp+ and at-003 Soaked in Hydrogen Peroxide To Be Published.
Page generated: Tue Jul 30 09:30:25 2024

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