Chlorine in PDB 8fhq: Cryo-Em Structure of Human Ncc (Class 3-2)

Other elements in 8fhq:

The structure of Cryo-Em Structure of Human Ncc (Class 3-2) also contains other interesting chemical elements:

Sodium (Na) 2 atoms
Fluorine (F) 6 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Cryo-Em Structure of Human Ncc (Class 3-2) (pdb code 8fhq). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Cryo-Em Structure of Human Ncc (Class 3-2), PDB code: 8fhq:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in 8fhq

Go back to Chlorine Binding Sites List in 8fhq
Chlorine binding site 1 out of 2 in the Cryo-Em Structure of Human Ncc (Class 3-2)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Cryo-Em Structure of Human Ncc (Class 3-2) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl1101

b:42.1
occ:1.00
CL01 A:XZF1101 0.0 42.1 1.0
C23 A:XZF1101 1.8 42.1 1.0
C21 A:XZF1101 2.7 42.1 1.0
C22 A:XZF1101 2.7 42.1 1.0
O10 A:XZF1101 3.0 42.1 1.0
S04 A:XZF1101 3.2 42.1 1.0
O11 A:XZF1101 3.2 42.1 1.0
CD1 A:LEU355 3.5 38.3 1.0
CG A:LEU355 3.5 38.3 1.0
CB A:LEU355 3.7 38.3 1.0
CE1 A:PHE223 3.9 36.2 1.0
CZ A:PHE223 4.0 36.2 1.0
C20 A:XZF1101 4.0 42.1 1.0
C17 A:XZF1101 4.0 42.1 1.0
CE1 A:TYR540 4.1 34.1 1.0
OH A:TYR540 4.2 34.1 1.0
CD1 A:PHE536 4.2 36.7 1.0
N A:LEU355 4.3 38.3 1.0
CE1 A:PHE536 4.4 36.7 1.0
CA A:GLY353 4.4 35.7 1.0
N A:GLY353 4.5 35.7 1.0
C16 A:XZF1101 4.5 42.1 1.0
CA A:LEU355 4.6 38.3 1.0
N A:ILE354 4.6 35.8 1.0
CZ A:TYR540 4.6 34.1 1.0
C A:GLY353 4.8 35.7 1.0
N14 A:XZF1101 4.9 42.1 1.0
CD2 A:LEU355 4.9 38.3 1.0

Chlorine binding site 2 out of 2 in 8fhq

Go back to Chlorine Binding Sites List in 8fhq
Chlorine binding site 2 out of 2 in the Cryo-Em Structure of Human Ncc (Class 3-2)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Cryo-Em Structure of Human Ncc (Class 3-2) within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl1101

b:42.2
occ:1.00
CL01 B:XZF1101 0.0 42.2 1.0
C23 B:XZF1101 1.8 42.2 1.0
C21 B:XZF1101 2.7 42.2 1.0
C22 B:XZF1101 2.7 42.2 1.0
O10 B:XZF1101 3.0 42.2 1.0
S04 B:XZF1101 3.2 42.2 1.0
O11 B:XZF1101 3.2 42.2 1.0
CD1 B:LEU355 3.5 38.1 1.0
CG B:LEU355 3.5 38.1 1.0
CB B:LEU355 3.7 38.1 1.0
CE1 B:PHE223 3.9 35.8 1.0
CZ B:PHE223 4.0 35.8 1.0
C20 B:XZF1101 4.0 42.2 1.0
C17 B:XZF1101 4.0 42.2 1.0
CE1 B:TYR540 4.1 34.4 1.0
OH B:TYR540 4.2 34.4 1.0
CD1 B:PHE536 4.2 36.8 1.0
N B:LEU355 4.3 38.1 1.0
CE1 B:PHE536 4.4 36.8 1.0
CA B:GLY353 4.4 35.6 1.0
N B:GLY353 4.5 35.6 1.0
C16 B:XZF1101 4.5 42.2 1.0
CA B:LEU355 4.6 38.1 1.0
N B:ILE354 4.6 35.7 1.0
CZ B:TYR540 4.6 34.4 1.0
C B:GLY353 4.8 35.6 1.0
N14 B:XZF1101 4.9 42.2 1.0
CD2 B:LEU355 4.9 38.1 1.0

Reference:

M.Fan, J.Zhang, C.Lee, J.Zhang, L.Feng. Structure and Thiazide Inhibition Mechanism of the Human Na-Cl Cotransporter Nature 2023.
ISSN: ESSN 1476-4687
DOI: 10.1038/S41586-023-05718-0
Page generated: Tue Apr 4 22:55:12 2023

Last articles

Cl in 3SNG
Cl in 3SN7
Cl in 3SN4
Cl in 3SN1
Cl in 3SN0
Cl in 3SMP
Cl in 3SMR
Cl in 3SMC
Cl in 3SMQ
Cl in 3SMN
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy