Chlorine in PDB 8fq5: GLUA2 Flip Q Isoform of Ampa Receptor in Complex with Gain-of-Function Tarp GAMMA2, with 140MM Nmdg, 330UM Ctz, and 100MM L-Glutamate (Open- NA110)

Chlorine Binding Sites:

The binding sites of Chlorine atom in the GLUA2 Flip Q Isoform of Ampa Receptor in Complex with Gain-of-Function Tarp GAMMA2, with 140MM Nmdg, 330UM Ctz, and 100MM L-Glutamate (Open- NA110) (pdb code 8fq5). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the GLUA2 Flip Q Isoform of Ampa Receptor in Complex with Gain-of-Function Tarp GAMMA2, with 140MM Nmdg, 330UM Ctz, and 100MM L-Glutamate (Open- NA110), PDB code: 8fq5:
Jump to Chlorine binding site number: 1; 2; 3; 4;

Chlorine binding site 1 out of 4 in 8fq5

Go back to Chlorine Binding Sites List in 8fq5
Chlorine binding site 1 out of 4 in the GLUA2 Flip Q Isoform of Ampa Receptor in Complex with Gain-of-Function Tarp GAMMA2, with 140MM Nmdg, 330UM Ctz, and 100MM L-Glutamate (Open- NA110)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of GLUA2 Flip Q Isoform of Ampa Receptor in Complex with Gain-of-Function Tarp GAMMA2, with 140MM Nmdg, 330UM Ctz, and 100MM L-Glutamate (Open- NA110) within 5.0Å range:
probe atom residue distance (Å) B Occ
E:Cl401

b:61.9
occ:1.00
 N E:TRP64 2.7 49.0 1.0
N E:ARG65 2.8 68.2 1.0
N E:LEU63 3.0 34.7 1.0
OD1 E:ASP31 3.1 57.5 1.0
CA E:GLY62 3.4 36.1 1.0
O E:ARG65 3.4 71.1 1.0
CA E:TRP64 3.5 48.8 1.0
C E:GLY62 3.5 33.5 1.0
CD1 E:TRP64 3.5 46.6 1.0
O E:THR30 3.6 39.2 1.0
C E:TRP64 3.6 49.7 1.0
C E:LEU63 3.7 41.1 1.0
CB E:TRP64 3.8 47.0 1.0
CA E:ARG65 3.8 69.3 1.0
CA E:LEU63 3.8 35.1 1.0
N E:GLY62 4.0 36.8 1.0
O E:HOH501 4.0 40.1 1.0
CG E:TRP64 4.0 48.8 1.0
CG E:ASP31 4.0 56.8 1.0
CA E:ASP31 4.0 53.4 1.0
C E:ARG65 4.1 71.2 1.0
CB E:ARG65 4.1 70.6 1.0
CB E:ASP31 4.2 53.7 1.0
C E:THR30 4.3 41.9 1.0
CG E:ARG65 4.5 71.4 1.0
O E:GLY62 4.5 33.6 1.0
CB E:LEU63 4.5 36.1 1.0
N E:ASP31 4.6 54.4 1.0
NE1 E:TRP64 4.7 44.0 1.0
O E:TRP64 4.8 52.1 1.0
O E:LEU63 4.9 39.5 1.0
CD E:ARG65 4.9 71.4 1.0

Chlorine binding site 2 out of 4 in 8fq5

Go back to Chlorine Binding Sites List in 8fq5
Chlorine binding site 2 out of 4 in the GLUA2 Flip Q Isoform of Ampa Receptor in Complex with Gain-of-Function Tarp GAMMA2, with 140MM Nmdg, 330UM Ctz, and 100MM L-Glutamate (Open- NA110)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of GLUA2 Flip Q Isoform of Ampa Receptor in Complex with Gain-of-Function Tarp GAMMA2, with 140MM Nmdg, 330UM Ctz, and 100MM L-Glutamate (Open- NA110) within 5.0Å range:
probe atom residue distance (Å) B Occ
G:Cl401

b:61.2
occ:1.00
 N G:TRP64 2.8 48.9 1.0
N G:ARG65 2.8 66.7 1.0
OD1 G:ASP31 3.2 56.9 1.0
N G:LEU63 3.2 33.8 1.0
CA G:GLY62 3.4 37.6 1.0
CA G:TRP64 3.5 49.5 1.0
C G:GLY62 3.5 34.3 1.0
O G:ARG65 3.5 69.9 1.0
C G:TRP64 3.6 50.5 1.0
O G:THR30 3.6 38.0 1.0
CD1 G:TRP64 3.7 46.8 1.0
CB G:TRP64 3.7 47.7 1.0
CA G:ARG65 3.8 67.7 1.0
C G:LEU63 3.8 40.2 1.0
O G:HOH501 3.9 40.4 1.0
CA G:ASP31 3.9 52.2 1.0
N G:GLY62 3.9 39.4 1.0
CB G:ARG65 4.0 69.5 1.0
CA G:LEU63 4.0 34.3 1.0
CG G:ASP31 4.0 55.4 1.0
CG G:TRP64 4.0 49.0 1.0
C G:ARG65 4.1 69.7 1.0
CB G:ASP31 4.1 52.6 1.0
C G:THR30 4.1 41.6 1.0
N G:ASP31 4.3 51.9 1.0
O G:GLY62 4.4 37.0 1.0
CB G:LEU63 4.6 33.7 1.0
CG G:ARG65 4.7 69.9 1.0
O G:TRP64 4.8 51.9 1.0
NE1 G:TRP64 4.8 44.2 1.0
CD G:ARG65 4.9 70.4 1.0
O G:LEU63 5.0 37.8 1.0

Chlorine binding site 3 out of 4 in 8fq5

Go back to Chlorine Binding Sites List in 8fq5
Chlorine binding site 3 out of 4 in the GLUA2 Flip Q Isoform of Ampa Receptor in Complex with Gain-of-Function Tarp GAMMA2, with 140MM Nmdg, 330UM Ctz, and 100MM L-Glutamate (Open- NA110)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of GLUA2 Flip Q Isoform of Ampa Receptor in Complex with Gain-of-Function Tarp GAMMA2, with 140MM Nmdg, 330UM Ctz, and 100MM L-Glutamate (Open- NA110) within 5.0Å range:
probe atom residue distance (Å) B Occ
F:Cl401

b:65.6
occ:1.00
 N F:TRP64 3.0 46.6 1.0
N F:ARG65 3.0 54.6 1.0
CD1 F:TRP64 3.3 49.1 1.0
N F:LEU63 3.5 38.8 1.0
CB F:TRP64 3.5 49.5 1.0
CB F:ASP31 3.5 56.0 1.0
CA F:TRP64 3.6 50.5 1.0
C F:TRP64 3.7 50.6 1.0
CG F:TRP64 3.7 50.5 1.0
O F:THR30 3.8 43.8 1.0
CA F:GLY62 3.9 33.7 1.0
CA F:ASP31 3.9 55.1 1.0
O F:ARG65 3.9 55.5 1.0
C F:GLY62 4.0 34.9 1.0
CA F:ARG65 4.0 55.0 1.0
CB F:ARG65 4.0 54.8 1.0
C F:LEU63 4.0 38.2 1.0
N F:GLY62 4.2 34.2 1.0
CA F:LEU63 4.2 39.3 1.0
C F:THR30 4.3 42.8 1.0
CD F:ARG65 4.3 55.8 1.0
CG F:ARG65 4.3 54.0 1.0
N F:ASP31 4.4 55.3 1.0
C F:ARG65 4.4 54.2 1.0
O F:GLY29 4.4 35.9 1.0
NE F:ARG65 4.5 56.5 1.0
NE1 F:TRP64 4.5 47.2 1.0
OD1 F:ASP31 4.5 58.2 1.0
CG F:ASP31 4.6 58.3 1.0
CB F:LEU63 4.8 39.9 1.0
O F:GLY62 4.9 37.3 1.0
O F:TRP64 4.9 52.3 1.0

Chlorine binding site 4 out of 4 in 8fq5

Go back to Chlorine Binding Sites List in 8fq5
Chlorine binding site 4 out of 4 in the GLUA2 Flip Q Isoform of Ampa Receptor in Complex with Gain-of-Function Tarp GAMMA2, with 140MM Nmdg, 330UM Ctz, and 100MM L-Glutamate (Open- NA110)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of GLUA2 Flip Q Isoform of Ampa Receptor in Complex with Gain-of-Function Tarp GAMMA2, with 140MM Nmdg, 330UM Ctz, and 100MM L-Glutamate (Open- NA110) within 5.0Å range:
probe atom residue distance (Å) B Occ
H:Cl401

b:67.2
occ:1.00
 N H:TRP64 3.0 48.4 1.0
N H:ARG65 3.0 54.9 1.0
CD1 H:TRP64 3.3 50.1 1.0
N H:LEU63 3.5 38.2 1.0
CB H:ASP31 3.5 54.5 1.0
CA H:TRP64 3.6 51.1 1.0
CB H:TRP64 3.6 50.2 1.0
C H:TRP64 3.7 51.2 1.0
CG H:TRP64 3.8 51.2 1.0
O H:THR30 3.8 44.5 1.0
CA H:GLY62 3.9 33.9 1.0
CA H:ASP31 3.9 54.1 1.0
C H:GLY62 3.9 34.8 1.0
CA H:ARG65 4.0 55.5 1.0
CB H:ARG65 4.0 55.5 1.0
O H:ARG65 4.0 56.5 1.0
C H:LEU63 4.0 39.3 1.0
N H:GLY62 4.2 35.0 1.0
CA H:LEU63 4.3 39.5 1.0
C H:THR30 4.3 43.6 1.0
CD H:ARG65 4.4 55.7 1.0
N H:ASP31 4.4 53.5 1.0
NE1 H:TRP64 4.4 48.7 1.0
C H:ARG65 4.5 55.2 1.0
O H:GLY29 4.5 35.8 1.0
OD1 H:ASP31 4.5 57.0 1.0
CG H:ASP31 4.6 56.6 1.0
NE H:ARG65 4.6 56.2 1.0
CG H:ARG65 4.6 54.8 1.0
CB H:LEU63 4.9 40.8 1.0
O H:GLY62 4.9 38.6 1.0
O H:TRP64 4.9 52.8 1.0

Reference:

T.Nakagawa, X.Wang, F.J.Miguez-Cabello, D.Bowie. Open Gate of Ampa Receptor Is A CA2+ Binding Site Critical to Ion Transport To Be Published.
Page generated: Tue Jul 30 09:43:11 2024

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