Chlorine in PDB 8fqf: GLUA2 Flip Q Isoform of Ampa Receptor in Complex with Gain-of-Function Tarp Gamma-2, with 150MM Nacl, 330UM Ctz, and 100MM Glutamate (Open- NA260)

The binding sites of Chlorine atom in the GLUA2 Flip Q Isoform of Ampa Receptor in Complex with Gain-of-Function Tarp Gamma-2, with 150MM Nacl, 330UM Ctz, and 100MM Glutamate (Open- NA260) (pdb code 8fqf). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the GLUA2 Flip Q Isoform of Ampa Receptor in Complex with Gain-of-Function Tarp Gamma-2, with 150MM Nacl, 330UM Ctz, and 100MM Glutamate (Open- NA260), PDB code: 8fqf:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the GLUA2 Flip Q Isoform of Ampa Receptor in Complex with Gain-of-Function Tarp Gamma-2, with 150MM Nacl, 330UM Ctz, and 100MM Glutamate (Open- NA260)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of GLUA2 Flip Q Isoform of Ampa Receptor in Complex with Gain-of-Function Tarp Gamma-2, with 150MM Nacl, 330UM Ctz, and 100MM Glutamate (Open- NA260) within 5.0Å range: probe atom residue distance (Å) B Occ F:Cl401 b:58.5 occ:1.00 N F:TRP64 2.8 39.0 1.0 N F:ARG65 2.9 49.1 1.0 N F:LEU63 3.2 31.4 1.0 O F:HOH501 3.2 37.1 1.0 CD1 F:TRP64 3.3 39.0 1.0 CB F:ASP31 3.4 47.0 1.0 CA F:TRP64 3.4 41.0 1.0 CA F:GLY62 3.5 29.3 1.0 CB F:TRP64 3.6 40.0 1.0 C F:GLY62 3.6 29.0 1.0 C F:TRP64 3.6 48.0 1.0 CG F:TRP64 3.7 40.8 1.0 C F:LEU63 3.8 32.1 1.0 O F:ARG65 3.9 47.9 1.0 CA F:ASP31 3.9 43.6 1.0 CA F:ARG65 3.9 49.1 1.0 N F:GLY62 3.9 36.1 1.0 CA F:LEU63 4.0 31.1 1.0 O F:THR30 4.0 39.3 1.0 CB F:ARG65 4.0 51.1 1.0 CG F:ARG65 4.2 53.7 1.0 C F:ARG65 4.4 49.0 1.0 CD F:ARG65 4.4 63.3 1.0 NE1 F:TRP64 4.4 34.5 1.0 C F:THR30 4.5 40.1 1.0 CG F:ASP31 4.5 49.6 1.0 OD1 F:ASP31 4.5 57.3 1.0 N F:ASP31 4.5 42.2 1.0 O F:GLY29 4.6 41.0 1.0 O F:GLY62 4.6 32.4 1.0 CB F:LEU63 4.6 31.3 1.0 O F:TRP64 4.9 53.5 1.0 O F:LEU63 4.9 36.1 1.0

Chlorine binding site 2 out of 2 in the GLUA2 Flip Q Isoform of Ampa Receptor in Complex with Gain-of-Function Tarp Gamma-2, with 150MM Nacl, 330UM Ctz, and 100MM Glutamate (Open- NA260)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of GLUA2 Flip Q Isoform of Ampa Receptor in Complex with Gain-of-Function Tarp Gamma-2, with 150MM Nacl, 330UM Ctz, and 100MM Glutamate (Open- NA260) within 5.0Å range: probe atom residue distance (Å) B Occ H:Cl401 b:61.0 occ:1.00 N H:TRP64 2.8 38.9 1.0 N H:ARG65 3.0 49.0 1.0 N H:LEU63 3.2 32.4 1.0 O H:HOH501 3.2 36.4 1.0 CD1 H:TRP64 3.3 39.5 1.0 CB H:ASP31 3.4 47.2 1.0 CA H:TRP64 3.5 41.8 1.0 CA H:GLY62 3.6 29.6 1.0 CB H:TRP64 3.6 41.0 1.0 C H:GLY62 3.7 29.7 1.0 C H:TRP64 3.7 48.1 1.0 CG H:TRP64 3.8 41.1 1.0 C H:LEU63 3.8 33.4 1.0 N H:GLY62 3.9 35.3 1.0 O H:ARG65 3.9 47.7 1.0 CA H:ASP31 3.9 44.0 1.0 CA H:ARG65 4.0 49.8 1.0 CA H:LEU63 4.0 32.5 1.0 O H:THR30 4.1 37.9 1.0 CB H:ARG65 4.1 51.7 1.0 CD H:ARG65 4.2 62.7 1.0 CG H:ARG65 4.4 56.4 1.0 C H:ARG65 4.4 49.4 1.0 NE1 H:TRP64 4.5 35.8 1.0 C H:THR30 4.5 39.5 1.0 N H:ASP31 4.5 42.2 1.0 CG H:ASP31 4.5 50.1 1.0 OD2 H:ASP31 4.6 58.3 1.0 O H:GLY29 4.6 40.8 1.0 O H:GLY62 4.6 33.2 1.0 CB H:LEU63 4.7 31.5 1.0 O H:TRP64 4.9 53.5 1.0 O H:LEU63 5.0 37.5 1.0

T.Nakagawa, X.Wang, F.J.Miguez-Cabello, D.Bowie. Open Gate of Ampa Receptor Is A CA2+ Binding Site Critical to Ion Transport To Be Published.