Chlorine in PDB 8fqg: Lbd Conformation 1 (LBDCONF1) of GLUA2 Flip Q Isoform of Ampa Receptor in Complex with Gain-of-Function Tarp Gamma-2, with 150MM Nacl, 330UM Ctz, and 100MM Glutamate (Open-NA260)

The binding sites of Chlorine atom in the Lbd Conformation 1 (LBDCONF1) of GLUA2 Flip Q Isoform of Ampa Receptor in Complex with Gain-of-Function Tarp Gamma-2, with 150MM Nacl, 330UM Ctz, and 100MM Glutamate (Open-NA260) (pdb code 8fqg). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the Lbd Conformation 1 (LBDCONF1) of GLUA2 Flip Q Isoform of Ampa Receptor in Complex with Gain-of-Function Tarp Gamma-2, with 150MM Nacl, 330UM Ctz, and 100MM Glutamate (Open-NA260), PDB code: 8fqg:
Jump to Chlorine binding site number: 1; 2; 3; 4;

Chlorine binding site 1 out of 4 in the Lbd Conformation 1 (LBDCONF1) of GLUA2 Flip Q Isoform of Ampa Receptor in Complex with Gain-of-Function Tarp Gamma-2, with 150MM Nacl, 330UM Ctz, and 100MM Glutamate (Open-NA260)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Lbd Conformation 1 (LBDCONF1) of GLUA2 Flip Q Isoform of Ampa Receptor in Complex with Gain-of-Function Tarp Gamma-2, with 150MM Nacl, 330UM Ctz, and 100MM Glutamate (Open-NA260) within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1302 b:69.6 occ:1.00 CL A:CYZ1302 0.0 69.6 1.0 C13 A:CYZ1302 1.8 31.7 1.0 C12 A:CYZ1302 2.7 26.2 1.0 C14 A:CYZ1302 2.8 24.3 1.0 O4 A:CYZ1302 2.9 40.2 1.0 N A:ASP760 3.2 31.9 1.0 S2 A:CYZ1302 3.2 45.6 1.0 CB A:LEU759 3.5 24.0 1.0 CA A:ASP760 3.5 35.5 1.0 N3 A:CYZ1302 3.6 42.4 1.0 C A:LEU759 3.6 33.1 1.0 CB A:ASP760 3.7 40.7 1.0 O A:HOH1401 3.8 5.8 1.0 C11 A:CYZ1302 4.0 23.3 1.0 C10 A:CYZ1302 4.1 24.6 1.0 CA A:LEU759 4.1 25.4 1.0 O A:LEU759 4.1 40.9 1.0 OD1 A:ASP760 4.5 56.5 1.0 CG A:ASP760 4.5 49.4 1.0 C9 A:CYZ1302 4.6 25.7 1.0 CG A:LEU759 4.7 27.2 1.0 CD1 A:LEU759 4.7 21.3 1.0 O3 A:CYZ1302 4.7 33.2 1.0 CB D:SER729 4.8 32.3 1.0 O A:PHE495 4.8 36.1 1.0 N A:LEU759 4.9 25.2 1.0 OG D:SER729 5.0 40.2 1.0

Chlorine binding site 2 out of 4 in the Lbd Conformation 1 (LBDCONF1) of GLUA2 Flip Q Isoform of Ampa Receptor in Complex with Gain-of-Function Tarp Gamma-2, with 150MM Nacl, 330UM Ctz, and 100MM Glutamate (Open-NA260)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Lbd Conformation 1 (LBDCONF1) of GLUA2 Flip Q Isoform of Ampa Receptor in Complex with Gain-of-Function Tarp Gamma-2, with 150MM Nacl, 330UM Ctz, and 100MM Glutamate (Open-NA260) within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl1302 b:86.1 occ:1.00 CL B:CYZ1302 0.0 86.1 1.0 C13 B:CYZ1302 1.8 47.5 1.0 C12 B:CYZ1302 2.7 40.2 1.0 C14 B:CYZ1302 2.8 42.0 1.0 O4 B:CYZ1302 2.9 44.8 1.0 OD1 B:ASP760 3.1 59.9 1.0 S2 B:CYZ1302 3.2 55.3 1.0 CG B:ASP760 3.2 60.7 1.0 O B:HOH1401 3.3 24.8 1.0 N B:ASP760 3.3 44.1 1.0 CB B:LEU759 3.4 34.4 1.0 OD2 B:ASP760 3.4 53.5 1.0 N3 B:CYZ1302 3.5 42.2 1.0 C B:LEU759 3.5 40.8 1.0 CA B:ASP760 3.6 46.4 1.0 O B:LEU759 3.9 45.5 1.0 CB B:ASP760 4.0 52.3 1.0 C11 B:CYZ1302 4.0 38.6 1.0 CA B:LEU759 4.1 36.1 1.0 C10 B:CYZ1302 4.1 41.1 1.0 O B:PHE495 4.4 37.8 1.0 C9 B:CYZ1302 4.6 41.0 1.0 CG B:LEU759 4.6 36.3 1.0 CD1 B:LEU759 4.6 37.9 1.0 O3 B:CYZ1302 4.7 49.5 1.0 OG C:SER729 4.8 50.8 1.0 C B:ASP760 5.0 53.5 1.0

Chlorine binding site 3 out of 4 in the Lbd Conformation 1 (LBDCONF1) of GLUA2 Flip Q Isoform of Ampa Receptor in Complex with Gain-of-Function Tarp Gamma-2, with 150MM Nacl, 330UM Ctz, and 100MM Glutamate (Open-NA260)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Lbd Conformation 1 (LBDCONF1) of GLUA2 Flip Q Isoform of Ampa Receptor in Complex with Gain-of-Function Tarp Gamma-2, with 150MM Nacl, 330UM Ctz, and 100MM Glutamate (Open-NA260) within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl1302 b:70.4 occ:1.00 CL C:CYZ1302 0.0 70.4 1.0 C13 C:CYZ1302 1.8 28.0 1.0 C12 C:CYZ1302 2.7 24.3 1.0 C14 C:CYZ1302 2.8 19.4 1.0 O4 C:CYZ1302 2.9 36.4 1.0 N C:ASP760 3.1 35.7 1.0 S2 C:CYZ1302 3.2 44.2 1.0 CB C:LEU759 3.5 25.2 1.0 CA C:ASP760 3.5 37.2 1.0 C C:LEU759 3.6 33.5 1.0 N3 C:CYZ1302 3.6 40.3 1.0 CB C:ASP760 3.7 43.4 1.0 O C:HOH1401 3.9 5.0 1.0 C11 C:CYZ1302 4.0 18.9 1.0 C10 C:CYZ1302 4.1 23.6 1.0 CA C:LEU759 4.1 24.3 1.0 O C:LEU759 4.1 38.1 1.0 OD1 C:ASP760 4.5 53.9 1.0 CG C:ASP760 4.5 51.6 1.0 C9 C:CYZ1302 4.6 23.4 1.0 CG C:LEU759 4.7 28.3 1.0 CD1 C:LEU759 4.7 21.1 1.0 CB B:SER729 4.7 30.8 1.0 O3 C:CYZ1302 4.8 32.5 1.0 O C:PHE495 4.8 34.4 1.0 N C:LEU759 4.8 26.0 1.0 C C:ASP760 5.0 39.7 1.0

Chlorine binding site 4 out of 4 in the Lbd Conformation 1 (LBDCONF1) of GLUA2 Flip Q Isoform of Ampa Receptor in Complex with Gain-of-Function Tarp Gamma-2, with 150MM Nacl, 330UM Ctz, and 100MM Glutamate (Open-NA260)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Lbd Conformation 1 (LBDCONF1) of GLUA2 Flip Q Isoform of Ampa Receptor in Complex with Gain-of-Function Tarp Gamma-2, with 150MM Nacl, 330UM Ctz, and 100MM Glutamate (Open-NA260) within 5.0Å range: probe atom residue distance (Å) B Occ D:Cl1302 b:87.1 occ:1.00 CL D:CYZ1302 0.0 87.1 1.0 C13 D:CYZ1302 1.8 47.9 1.0 C12 D:CYZ1302 2.7 42.5 1.0 C14 D:CYZ1302 2.8 41.5 1.0 O4 D:CYZ1302 2.9 43.3 1.0 S2 D:CYZ1302 3.2 56.6 1.0 N D:ASP760 3.2 42.3 1.0 CA D:ASP760 3.4 47.4 1.0 CB D:LEU759 3.4 38.8 1.0 O D:HOH1402 3.5 30.4 1.0 N3 D:CYZ1302 3.5 45.1 1.0 CB D:ASP760 3.5 51.8 1.0 C D:LEU759 3.5 40.5 1.0 C11 D:CYZ1302 4.0 41.8 1.0 O D:LEU759 4.0 47.4 1.0 C10 D:CYZ1302 4.1 42.4 1.0 CA D:LEU759 4.1 37.4 1.0 O D:PHE495 4.5 42.5 1.0 C9 D:CYZ1302 4.6 42.8 1.0 CD1 D:LEU759 4.7 38.0 1.0 CG D:LEU759 4.7 39.6 1.0 O3 D:CYZ1302 4.8 51.5 1.0 CG D:ASP760 4.8 59.8 1.0 C D:ASP760 4.9 54.9 1.0 OG A:SER729 4.9 50.2 1.0 CB A:SER729 4.9 41.1 1.0

T.Nakagawa, X.Wang, F.J.Miguez-Cabello, D.Bowie. Open Gate of Ampa Receptor Is A CA2+ Binding Site Critical to Ion Transport To Be Published.