Chlorine in PDB 8fz4: The Von Willebrand Factor A Domain of Anthrax Toxin Receptor 2

The structure of The Von Willebrand Factor A Domain of Anthrax Toxin Receptor 2, PDB code: 8fz4 was solved by M.J.Pedroza-Romo, S.Soleimani, A.Lewis, T.Smith, S.Brown, T.Doukov, J.D.Moody, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	39.08 / 2.19
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	78.244, 88.969, 59.779, 90, 128.13, 90
R / Rfree (%)	21.8 / 25.6

The structure of The Von Willebrand Factor A Domain of Anthrax Toxin Receptor 2 also contains other interesting chemical elements:

Magnesium

(Mg)

2 atoms

The binding sites of Chlorine atom in the The Von Willebrand Factor A Domain of Anthrax Toxin Receptor 2 (pdb code 8fz4). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the The Von Willebrand Factor A Domain of Anthrax Toxin Receptor 2, PDB code: 8fz4:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the The Von Willebrand Factor A Domain of Anthrax Toxin Receptor 2


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of The Von Willebrand Factor A Domain of Anthrax Toxin Receptor 2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl302 b:63.0 occ:1.00 OG1 A:THR118 3.1 44.3 1.0 O A:HOH414 3.2 39.6 1.0 O A:GLY116 3.2 48.4 1.0 N A:SER54 3.4 46.9 1.0 CB A:SER52 3.4 38.7 1.0 N A:GLY53 3.6 46.2 1.0 OG A:SER52 3.7 46.9 1.0 CB A:SER54 3.7 46.8 1.0 MG A:MG301 3.7 49.3 1.0 OG A:SER54 3.8 45.2 1.0 CA A:SER54 4.2 47.2 1.0 CA A:GLY53 4.2 47.7 1.0 C A:GLY53 4.2 47.7 1.0 C A:GLU117 4.3 45.6 1.0 C A:SER52 4.3 40.1 1.0 C A:GLY116 4.4 48.1 1.0 CA A:SER52 4.5 46.1 1.0 CA A:GLU117 4.5 47.6 1.0 O A:GLU117 4.5 44.6 1.0 CB A:THR118 4.5 43.6 1.0 N A:THR118 4.6 45.1 1.0 N A:GLU117 4.9 48.2 1.0

Chlorine binding site 2 out of 2 in the The Von Willebrand Factor A Domain of Anthrax Toxin Receptor 2


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of The Von Willebrand Factor A Domain of Anthrax Toxin Receptor 2 within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl302 b:65.9 occ:1.00 MG B:MG301 2.5 46.3 1.0 OG1 B:THR118 3.1 46.8 1.0 N B:SER54 3.3 48.2 1.0 OG B:SER52 3.3 45.2 1.0 CB B:SER52 3.4 44.7 1.0 OG B:SER54 3.4 45.8 1.0 O B:GLY116 3.4 47.0 1.0 CB B:SER54 3.5 48.5 1.0 N B:GLY53 3.7 48.5 1.0 CA B:SER54 4.0 48.9 1.0 C B:GLY53 4.2 49.2 1.0 C B:SER52 4.2 47.2 1.0 CA B:GLY53 4.2 49.1 1.0 O B:HOH447 4.3 41.7 1.0 C B:GLU117 4.4 48.5 1.0 CA B:SER52 4.4 45.2 1.0 CA B:GLU117 4.5 51.2 1.0 CB B:THR118 4.5 41.3 1.0 C B:GLY116 4.5 51.7 1.0 N B:THR118 4.6 43.3 1.0 O B:GLU117 4.6 43.8 1.0

P.L.Gajjar, M.J.Pedroza-Romo, C.Litchfield, M.Callahan, N.Redd, S.Nawarathnage, E.Wilson, J.Averett, S.Soleimani, A.Lewis, T.Smith, S.Brown, T.Doukov, A.Lebedev, J.D.Moody. Decreasing the Flexibility of the Telsam-Target Protein Linker and Omitting the Cleavable Fusion Tag Improves Crystal Order and Diffraction Limits To Be Published.