Chlorine in PDB 8g1w: Crystal Structure Matriptase (C731S) in Complex with Inhibitor VD4162B

All present enzymatic activity of Crystal Structure Matriptase (C731S) in Complex with Inhibitor VD4162B:
3.4.21.109;

The structure of Crystal Structure Matriptase (C731S) in Complex with Inhibitor VD4162B, PDB code: 8g1w was solved by S.Lovell, M.M.Kashipathy, K.P.Battaile, J.W.Janetka, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	31.37 / 1.20
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	75.259, 80.248, 40.361, 90, 95.45, 90
R / Rfree (%)	14.8 / 16.6

The binding sites of Chlorine atom in the Crystal Structure Matriptase (C731S) in Complex with Inhibitor VD4162B (pdb code 8g1w). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure Matriptase (C731S) in Complex with Inhibitor VD4162B, PDB code: 8g1w:

Chlorine binding site 1 out of 1 in the Crystal Structure Matriptase (C731S) in Complex with Inhibitor VD4162B


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure Matriptase (C731S) in Complex with Inhibitor VD4162B within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl901 b:44.0 occ:1.00 NH2 A:ARG769 3.2 19.2 1.0 NE A:ARG769 3.2 17.2 1.0 CZ A:ARG769 3.7 18.6 1.0 O A:HOH1165 3.7 26.4 1.0 CE1 A:PHE793 4.1 15.5 1.0 CD A:ARG769 4.4 16.7 1.0 CZ A:PHE793 4.5 15.4 1.0 NH1 A:ARG769 5.0 17.8 1.0

S.Lovell, J.W.Janetka. Crystal Structure Matriptase (C731S) in Complex with Inhibitor VD4162B To Be Published.