Chlorine in PDB 8gkv: Crystal Structure of Anti-Adaptor Irap That Regulates Rpos Proteolysis

The structure of Crystal Structure of Anti-Adaptor Irap That Regulates Rpos Proteolysis, PDB code: 8gkv was solved by G.X.Shaw, J.Gan, P.Suburaman, A.Battesti, Y.N.Zhou, S.Wickner, S.Gottesman, X.Ji, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.06 / 2.35
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	75.335, 57.013, 48.629, 90, 129.5, 90
R / Rfree (%)	21.5 / 23.9

The binding sites of Chlorine atom in the Crystal Structure of Anti-Adaptor Irap That Regulates Rpos Proteolysis (pdb code 8gkv). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 8 binding sites of Chlorine where determined in the Crystal Structure of Anti-Adaptor Irap That Regulates Rpos Proteolysis, PDB code: 8gkv:
Jump to Chlorine binding site number: 1; 2; 3; 4; 5; 6; 7; 8;

Chlorine binding site 1 out of 8 in the Crystal Structure of Anti-Adaptor Irap That Regulates Rpos Proteolysis


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Anti-Adaptor Irap That Regulates Rpos Proteolysis within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl105 b:93.7 occ:1.00 HD11 A:LEU8 3.2 49.9 1.0 HZ2 A:LYS11 3.3 110.9 1.0 O A:HOH220 3.6 48.0 1.0 HD3 A:LYS11 3.6 85.9 1.0 HD13 A:LEU8 3.6 49.9 1.0 CD1 A:LEU8 3.8 41.6 1.0 HB3 A:GLU7 3.9 43.4 1.0 HD12 A:LEU4 3.9 50.6 1.0 HD11 A:LEU4 4.0 50.6 1.0 HD12 A:LEU8 4.1 49.9 1.0 NZ A:LYS11 4.1 92.4 1.0 HZ3 A:LYS11 4.1 110.9 1.0 CD1 A:LEU4 4.3 42.1 1.0 HB2 A:GLU7 4.4 43.4 1.0 HD13 A:LEU4 4.4 50.6 1.0 CD A:LYS11 4.5 71.6 1.0 CB A:GLU7 4.6 36.1 1.0 HD2 A:LYS11 4.7 85.9 1.0 HZ1 A:LYS11 4.7 110.9 1.0 HA A:LEU8 4.8 40.0 1.0 CE A:LYS11 4.8 87.1 1.0

Chlorine binding site 2 out of 8 in the Crystal Structure of Anti-Adaptor Irap That Regulates Rpos Proteolysis


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Anti-Adaptor Irap That Regulates Rpos Proteolysis within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl106 b:64.5 occ:1.00 HE1 A:PHE10 3.6 70.3 1.0 HB1 A:ALA13 3.9 38.9 1.0 CE1 A:PHE10 4.2 58.6 1.0 HB3 A:ALA13 4.3 38.9 1.0 CB A:ALA13 4.5 32.4 1.0 HG3 A:GLU17 4.6 83.5 1.0 HD1 A:PHE10 4.7 66.3 1.0 HZ A:PHE10 4.8 71.2 1.0 CD1 A:PHE10 4.8 55.2 1.0 CZ A:PHE10 4.8 59.3 1.0

Chlorine binding site 3 out of 8 in the Crystal Structure of Anti-Adaptor Irap That Regulates Rpos Proteolysis


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Crystal Structure of Anti-Adaptor Irap That Regulates Rpos Proteolysis within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl107 b:68.2 occ:1.00 HB2 A:ALA41 3.1 73.8 1.0 CB A:ALA41 3.9 61.5 1.0 HB1 A:ALA41 4.1 73.8 1.0 HB3 A:ALA41 4.2 73.8 1.0 HA A:ARG38 4.3 50.9 1.0 HB3 A:LEU37 4.4 48.5 1.0 O A:LEU37 4.5 52.6 1.0 HG2 A:ARG38 4.8 65.6 1.0 C A:LEU37 4.9 44.3 1.0

Chlorine binding site 4 out of 8 in the Crystal Structure of Anti-Adaptor Irap That Regulates Rpos Proteolysis


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Crystal Structure of Anti-Adaptor Irap That Regulates Rpos Proteolysis within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl108 b:81.9 occ:1.00 HB3 A:GLU27 3.6 46.5 1.0 HB2 A:ALA28 4.0 42.6 1.0 HG2 A:GLU27 4.1 62.4 1.0 H A:ALA28 4.2 32.7 1.0 HD12 A:ILE31 4.2 57.6 1.0 O A:ALA24 4.2 34.1 1.0 HA A:ALA28 4.2 41.6 1.0 OE1 A:GLU27 4.2 66.4 1.0 CD A:GLU27 4.3 66.0 1.0 N A:ALA28 4.4 27.3 1.0 HA A:ALA24 4.4 48.4 1.0 CB A:GLU27 4.4 38.8 1.0 CG A:GLU27 4.4 52.0 1.0 HB1 A:ALA24 4.5 48.2 1.0 CA A:ALA28 4.7 34.7 1.0 OE2 A:GLU27 4.7 70.7 1.0 HD11 A:ILE31 4.7 57.6 1.0 CB A:ALA28 4.8 35.5 1.0 CD1 A:ILE31 4.8 48.0 1.0 C A:GLU27 4.9 29.8 1.0 HD13 A:ILE31 5.0 57.6 1.0 HB2 A:GLU27 5.0 46.5 1.0

Chlorine binding site 5 out of 8 in the Crystal Structure of Anti-Adaptor Irap That Regulates Rpos Proteolysis


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 5 of Crystal Structure of Anti-Adaptor Irap That Regulates Rpos Proteolysis within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl109 b:65.9 occ:1.00 HG A:LEU22 3.6 43.4 1.0 HD22 A:LEU22 3.6 40.6 1.0 HE22 A:GLN25 3.7 77.7 1.0 HG3 A:GLU18 3.8 72.7 1.0 HD21 A:LEU22 4.0 40.6 1.0 CD2 A:LEU22 4.1 33.8 1.0 O A:HOH206 4.2 54.0 1.0 CG A:LEU22 4.3 36.2 1.0 HB2 A:GLU21 4.3 51.2 1.0 OE1 A:GLU21 4.4 82.6 1.0 NE2 A:GLN25 4.4 64.8 1.0 HD13 A:LEU22 4.5 39.8 1.0 HB3 A:GLU21 4.5 51.2 1.0 HA A:GLU18 4.7 45.6 1.0 CG A:GLU18 4.7 60.6 1.0 O A:GLU18 4.8 35.7 1.0 CB A:GLU21 4.9 42.7 1.0 HE21 A:GLN25 4.9 77.7 1.0 CD1 A:LEU22 4.9 33.2 1.0 HG2 A:GLU18 5.0 72.7 1.0

Chlorine binding site 6 out of 8 in the Crystal Structure of Anti-Adaptor Irap That Regulates Rpos Proteolysis


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 6 of Crystal Structure of Anti-Adaptor Irap That Regulates Rpos Proteolysis within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl102 b:77.7 occ:1.00 HB3 B:MET1 2.8 71.5 1.0 HG2 B:LYS2 3.1 83.4 1.0 O B:HOH205 3.2 96.6 1.0 HB2 B:MET1 3.5 71.5 1.0 H B:LYS2 3.5 83.2 1.0 CB B:MET1 3.6 59.6 1.0 HG3 B:LYS2 3.6 83.4 1.0 HE2 B:LYS2 3.8 92.9 1.0 CG B:LYS2 3.8 69.5 1.0 H B:MET1 3.9 54.4 1.0 HE1 A:MET1 3.9 98.0 1.0 N B:LYS2 4.2 69.3 1.0 HE3 B:LYS2 4.2 92.9 1.0 HG2 B:MET1 4.3 90.6 1.0 CE B:LYS2 4.4 77.4 1.0 CG B:MET1 4.5 75.5 1.0 CA B:MET1 4.5 55.9 1.0 N B:MET1 4.6 45.3 1.0 CD B:LYS2 4.7 74.5 1.0 CE A:MET1 4.8 81.6 1.0 C B:MET1 4.8 63.5 1.0 CB B:LYS2 4.9 64.5 1.0 HG3 B:MET1 4.9 90.6 1.0 HB2 B:LYS2 5.0 77.4 1.0

Chlorine binding site 7 out of 8 in the Crystal Structure of Anti-Adaptor Irap That Regulates Rpos Proteolysis


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 7 of Crystal Structure of Anti-Adaptor Irap That Regulates Rpos Proteolysis within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl103 b:79.7 occ:1.00 HG2 B:GLN25 3.5 44.7 1.0 HA B:GLN25 3.7 45.5 1.0 HB1 B:ALA24 3.9 49.7 1.0 HB2 B:ALA28 4.0 45.8 1.0 HG3 B:GLN25 4.3 44.7 1.0 HB3 B:ALA24 4.3 49.7 1.0 CG B:GLN25 4.3 37.3 1.0 N B:GLN25 4.4 44.3 1.0 CA B:GLN25 4.4 37.9 1.0 HB3 B:ALA28 4.4 45.8 1.0 C B:ALA24 4.5 43.7 1.0 CB B:ALA24 4.5 41.4 1.0 O B:ALA24 4.5 39.1 1.0 H B:GLN25 4.6 53.2 1.0 CB B:ALA28 4.6 38.1 1.0 HB1 B:ALA28 4.9 45.8 1.0 CB B:GLN25 5.0 29.9 1.0

Chlorine binding site 8 out of 8 in the Crystal Structure of Anti-Adaptor Irap That Regulates Rpos Proteolysis


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 8 of Crystal Structure of Anti-Adaptor Irap That Regulates Rpos Proteolysis within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl104 b:72.6 occ:1.00 HG2 B:GLU30 3.8 56.1 1.0 HG11 B:VAL33 4.0 53.1 1.0 HG12 B:VAL33 4.1 53.1 1.0 HG1 B:THR34 4.2 52.2 1.0 HB B:VAL33 4.2 48.1 1.0 HA B:GLU30 4.3 49.6 1.0 CG1 B:VAL33 4.4 44.2 1.0 HD21 A:LEU29 4.5 25.5 1.0 HB3 B:GLU30 4.6 53.2 1.0 OG1 B:THR34 4.6 43.5 1.0 CG B:GLU30 4.7 46.8 1.0 HD12 B:LEU37 4.8 61.8 1.0 O B:GLU30 4.8 36.0 1.0 CB B:VAL33 4.9 40.1 1.0 HD11 B:LEU37 4.9 61.8 1.0 CB B:GLU30 5.0 44.4 1.0

A.Tripathi, J.Hoskins, G.X.Shaw, J.Gan, S.Tong, A.Battesti, L.M.Jenkins, X.Ji, S.Wickner, S.Gottesman. Structural and Functional Study of Anti-Adaptor Irap-Mediated Regulation of Rpos Proteolysis To Be Published.