Chlorine in PDB 8hfi: Cryo-Em Structure of Human Norepinephrine Transporter Net in the Presence of the Antidepressant Desipramine in An Inward-Open State at Resolution of 2.5 Angstrom.

The binding sites of Chlorine atom in the Cryo-Em Structure of Human Norepinephrine Transporter Net in the Presence of the Antidepressant Desipramine in An Inward-Open State at Resolution of 2.5 Angstrom. (pdb code 8hfi). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Cryo-Em Structure of Human Norepinephrine Transporter Net in the Presence of the Antidepressant Desipramine in An Inward-Open State at Resolution of 2.5 Angstrom., PDB code: 8hfi:

Chlorine binding site 1 out of 1 in the Cryo-Em Structure of Human Norepinephrine Transporter Net in the Presence of the Antidepressant Desipramine in An Inward-Open State at Resolution of 2.5 Angstrom.


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Cryo-Em Structure of Human Norepinephrine Transporter Net in the Presence of the Antidepressant Desipramine in An Inward-Open State at Resolution of 2.5 Angstrom. within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl702 b:27.9 occ:1.00 OG A:SER354 2.5 16.8 1.0 OG A:SER318 2.8 14.5 1.0 OH A:TYR98 2.9 18.6 1.0 NE2 A:GLN314 3.1 6.8 1.0 ND2 A:ASN78 3.2 22.6 1.0 CD2 A:PHE82 3.4 10.8 1.0 CB A:PHE82 3.7 6.9 1.0 CB A:SER354 3.7 14.3 1.0 CB A:SER318 3.7 12.0 1.0 CG A:PHE82 3.8 7.5 1.0 CZ A:TYR98 3.8 13.4 1.0 CG A:ASN78 3.8 17.1 1.0 CA A:ASN78 3.9 11.0 1.0 CD A:GLN314 4.1 7.4 1.0 CE1 A:TYR98 4.2 11.3 1.0 CG A:GLN314 4.2 7.3 1.0 CB A:ASN78 4.2 14.7 1.0 N A:ASN78 4.3 13.1 1.0 CE2 A:PHE82 4.3 12.8 1.0 ND2 A:ASN350 4.4 24.6 1.0 OD1 A:ASN78 4.6 12.9 1.0 C A:ALA77 4.6 12.4 1.0 CA A:SER354 4.7 14.1 1.0 CE2 A:TYR98 4.8 9.4 1.0 O A:ALA77 4.8 16.3 1.0 CA A:PHE82 4.9 11.0 1.0 CD1 A:PHE82 4.9 8.6 1.0 CA A:SER318 5.0 12.0 1.0

J.Tan, Y.Xiao, F.Kong, J.Lei, Y.Yuan, C.Yan. Molecular Basis For the Reuptake and Inhibition of Human Norepinephrine Transporter To Be Published.