Chlorine in PDB 8hnn: Structure of CXCR3 Complexed with Antagonist SCH546738

The binding sites of Chlorine atom in the Structure of CXCR3 Complexed with Antagonist SCH546738 (pdb code 8hnn). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Structure of CXCR3 Complexed with Antagonist SCH546738, PDB code: 8hnn:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Structure of CXCR3 Complexed with Antagonist SCH546738


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of CXCR3 Complexed with Antagonist SCH546738 within 5.0Å range: probe atom residue distance (Å) B Occ R:Cl401 b:62.0 occ:1.00 CL1 R:43I401 0.0 62.0 1.0 C16 R:43I401 1.7 62.0 1.0 C15 R:43I401 2.7 62.0 1.0 C17 R:43I401 2.7 62.0 1.0 CE1 R:PHE272 3.4 44.1 1.0 CD1 R:PHE272 3.8 44.1 1.0 C14 R:43I401 3.9 62.0 1.0 C18 R:43I401 3.9 62.0 1.0 CE1 R:PHE135 4.4 54.9 1.0 CB R:ALA139 4.4 43.9 1.0 CE R:MET231 4.4 46.5 1.0 C13 R:43I401 4.5 62.0 1.0 CD1 R:PHE224 4.5 58.6 1.0 CZ R:PHE272 4.6 44.1 1.0 CE1 R:PHE224 4.6 58.6 1.0 CZ R:PHE135 4.7 54.9 1.0 CA R:ALA139 4.8 43.9 1.0 CB R:PRO227 4.8 47.3 1.0 O R:GLY223 5.0 53.5 1.0

Chlorine binding site 2 out of 2 in the Structure of CXCR3 Complexed with Antagonist SCH546738


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Structure of CXCR3 Complexed with Antagonist SCH546738 within 5.0Å range: probe atom residue distance (Å) B Occ R:Cl401 b:62.0 occ:1.00 CL2 R:43I401 0.0 62.0 1.0 C22 R:43I401 1.7 62.0 1.0 C4 R:43I401 2.4 62.0 1.0 N5 R:43I401 2.6 62.0 1.0 C19 R:43I401 2.7 62.0 1.0 N1 R:43I401 2.9 62.0 1.0 C2 R:43I401 3.1 62.0 1.0 C3 R:43I401 3.2 62.0 1.0 C21 R:43I401 3.9 62.0 1.0 N4 R:43I401 3.9 62.0 1.0 C5 R:43I401 4.3 62.0 1.0 C20 R:43I401 4.4 62.0 1.0 C1 R:43I401 4.5 62.0 1.0 N2 R:43I401 4.5 62.0 1.0 C6 R:43I401 4.9 62.0 1.0

H.Jiao, B.Pang, A.Liu, Q.Chen, Q.Pan, X.Wang, Y.Xu, Y.Chiang, R.Ren, H.Hu. Structural Insights Into the Activation and Inhibition of Cxc Chemokine Receptor 3 Nat.Struct.Mol.Biol. 2023.
ISSN: ESSN 1545-9985
DOI: 10.1038/S41594-023-01175-5