Chlorine in PDB 8hq5: G6 in Complex with CRM1-Ran-RANBP1

The structure of G6 in Complex with CRM1-Ran-RANBP1, PDB code: 8hq5 was solved by Q.Sun, Y.Lei, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.01 / 2.25
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	105.58, 105.58, 304.909, 90, 90, 90
R / Rfree (%)	17.5 / 20.9

The structure of G6 in Complex with CRM1-Ran-RANBP1 also contains other interesting chemical elements:

Magnesium	(Mg)	1 atom
Bromine	(Br)	1 atom

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 12;

Binding sites:

The binding sites of Chlorine atom in the G6 in Complex with CRM1-Ran-RANBP1 (pdb code 8hq5). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 12 binding sites of Chlorine where determined in the G6 in Complex with CRM1-Ran-RANBP1, PDB code: 8hq5:
Jump to Chlorine binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Chlorine binding site 1 out of 12 in the G6 in Complex with CRM1-Ran-RANBP1


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of G6 in Complex with CRM1-Ran-RANBP1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl304 b:89.3 occ:1.00 O A:HOH472 3.5 62.2 1.0 O A:PRO49 3.6 55.9 1.0 N A:VAL51 3.9 53.2 1.0 CA A:LEU50 4.1 53.0 1.0 C A:PRO49 4.4 54.6 1.0 C A:LEU50 4.5 53.6 1.0 CD1 A:LEU50 4.5 54.8 1.0 CG2 A:VAL51 4.6 60.8 1.0 CD2 A:LEU31 4.6 56.3 1.0 CB A:VAL51 4.6 59.7 1.0 N A:LEU50 4.6 53.7 1.0 CA A:VAL51 4.8 55.3 1.0 O A:LEU31 4.9 49.9 1.0 O A:VAL51 5.0 53.0 1.0

Chlorine binding site 2 out of 12 in the G6 in Complex with CRM1-Ran-RANBP1


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of G6 in Complex with CRM1-Ran-RANBP1 within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl1101 b:93.8 occ:1.00 O C:HOH1482 3.5 63.8 1.0 CD C:LYS567 3.6 59.2 1.0 NE2 C:HIS609 3.7 55.0 1.0 CE C:LYS567 3.8 62.9 1.0 CD2 C:HIS609 3.9 55.6 1.0 NZ C:LYS567 4.0 66.3 1.0 CB C:TYR608 4.2 64.2 1.0 CG C:LYS567 4.2 55.3 1.0 CD2 C:TYR608 4.4 70.3 1.0 CG C:TYR608 4.6 67.8 1.0 O C:HOH1557 4.7 73.5 1.0 CE1 C:HIS609 4.9 57.5 1.0 CB C:LYS567 4.9 53.7 1.0

Chlorine binding site 3 out of 12 in the G6 in Complex with CRM1-Ran-RANBP1


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of G6 in Complex with CRM1-Ran-RANBP1 within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl1102 b:78.6 occ:1.00 N C:ALA328 3.7 51.2 1.0 O C:ARG325 3.7 45.7 1.0 CB C:ALA328 3.9 52.2 1.0 N C:ARG327 3.9 49.1 1.0 O C:HOH1596 4.0 69.6 1.0 C C:ARG325 4.0 49.2 1.0 O C:ALA324 4.0 49.5 1.0 CG C:ARG327 4.1 51.7 1.0 N C:ASN326 4.3 48.8 1.0 CA C:ALA328 4.4 52.4 1.0 O C:LEU323 4.4 45.3 1.0 C C:ASN326 4.4 48.8 1.0 C C:ARG327 4.6 49.6 1.0 CA C:ARG327 4.6 52.5 1.0 O C:HOH1473 4.7 56.3 1.0 CA C:ASN326 4.7 48.7 1.0 C C:ALA324 4.7 45.9 1.0 NE C:ARG327 4.8 50.1 1.0 CA C:ARG325 4.8 49.5 1.0 CB C:ARG327 4.9 51.9 1.0 CZ C:ARG327 5.0 51.2 1.0

Chlorine binding site 4 out of 12 in the G6 in Complex with CRM1-Ran-RANBP1


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of G6 in Complex with CRM1-Ran-RANBP1 within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl1103 b:92.2 occ:1.00 NH1 C:ARG77 3.2 95.2 1.0 NE2 C:HIS1005 3.9 49.5 1.0 O C:LYS1040 4.0 51.4 1.0 CD2 C:HIS1005 4.1 49.1 1.0 O C:ILE1039 4.1 48.9 1.0 C C:LYS1040 4.2 48.5 1.0 CE1 C:HIS1005 4.2 49.5 1.0 N C:GLU1041 4.4 48.0 1.0 CG C:HIS1005 4.4 48.8 1.0 CZ C:ARG77 4.5 91.4 1.0 ND1 C:HIS1005 4.5 50.8 1.0 CA C:GLU1041 4.5 50.1 1.0 O C:GLU1041 4.5 48.2 1.0 C C:GLU1041 4.6 48.8 1.0 CG2 C:VAL1042 4.7 47.7 1.0 CA C:LYS1040 4.8 50.6 1.0

Chlorine binding site 5 out of 12 in the G6 in Complex with CRM1-Ran-RANBP1


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 5 of G6 in Complex with CRM1-Ran-RANBP1 within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl1104 b:99.1 occ:1.00 CB C:SER187 4.2 57.6 1.0 OG C:SER187 4.2 58.9 1.0 OD1 C:ASN184 4.2 52.4 1.0 O C:LYS183 4.2 47.4 1.0 CB C:LYS183 4.3 49.1 1.0 C C:LYS183 4.3 50.5 1.0 CE1 C:PHE167 4.4 45.9 1.0 CZ C:PHE167 4.5 47.9 1.0 N C:ASN184 4.6 49.0 1.0 CA C:LYS183 4.9 50.1 1.0 CA C:ASN184 4.9 49.5 1.0

Chlorine binding site 6 out of 12 in the G6 in Complex with CRM1-Ran-RANBP1


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 6 of G6 in Complex with CRM1-Ran-RANBP1 within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl1107 b:88.4 occ:1.00 O C:HOH1541 3.5 69.2 1.0 O C:HOH1428 3.8 67.2 1.0 CB C:TRP891 4.0 50.6 1.0 CB C:ASN846 4.1 52.8 1.0 CG C:TRP891 4.1 49.5 1.0 O C:ASP887 4.1 53.5 1.0 CD2 C:TRP891 4.2 51.0 1.0 CE3 C:TRP891 4.3 52.4 1.0 CB C:ASP887 4.3 57.2 1.0 C C:ASP887 4.5 54.0 1.0 ND2 C:ASN846 4.5 50.9 1.0 CD1 C:TRP891 4.8 50.9 1.0 CG C:ASN846 4.8 52.9 1.0 CE2 C:TRP891 4.9 51.0 1.0 CA C:ASP887 4.9 54.0 1.0

Chlorine binding site 7 out of 12 in the G6 in Complex with CRM1-Ran-RANBP1


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 7 of G6 in Complex with CRM1-Ran-RANBP1 within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl1108 b:106.0 occ:1.00 O C:HOH1512 3.3 47.5 1.0 OE1 C:GLU839 3.5 71.0 1.0 CD2 C:LEU877 3.8 72.8 1.0 CB C:ALA881 4.2 61.2 1.0 CA C:GLN835 4.3 57.0 1.0 CD C:GLU839 4.4 63.5 1.0 CG C:GLU839 4.4 59.4 1.0 CD2 C:PHE838 4.4 52.6 1.0 CG C:GLN835 4.8 62.0 1.0 O C:LEU834 4.8 56.6 1.0 N C:GLN835 4.8 53.3 1.0 O C:GLN835 5.0 63.0 1.0

Chlorine binding site 8 out of 12 in the G6 in Complex with CRM1-Ran-RANBP1


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 8 of G6 in Complex with CRM1-Ran-RANBP1 within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl1110 b:99.3 occ:1.00 OG1 C:THR944 3.9 53.0 1.0 CB C:ALA1002 3.9 48.1 1.0 CA C:PHE941 4.1 58.8 1.0 N C:PHE941 4.1 55.3 1.0 C C:PHE940 4.3 52.6 1.0 CE2 C:PHE1003 4.3 45.6 1.0 O C:PHE940 4.4 51.8 1.0 CB C:PHE940 4.5 53.6 1.0 CZ C:PHE1003 4.6 44.9 1.0 CE C:MET998 4.7 55.9 1.0 CB C:PHE941 4.7 64.3 1.0 CD1 C:PHE941 4.8 74.0 1.0 SD C:MET998 4.9 54.9 1.0 CG C:MET998 5.0 52.0 1.0 O C:SER937 5.0 51.2 1.0

Chlorine binding site 9 out of 12 in the G6 in Complex with CRM1-Ran-RANBP1


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 9 of G6 in Complex with CRM1-Ran-RANBP1 within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl1111 b:72.0 occ:1.00 O C:HOH1382 3.4 48.4 1.0 CB C:GLU357 3.9 44.0 1.0 CD C:GLN313 3.9 43.6 1.0 O A:LEU144 4.1 43.2 1.0 CG C:GLN313 4.1 44.1 1.0 OE1 C:GLN313 4.1 45.8 1.0 NE2 C:GLN313 4.1 41.3 1.0 N C:LEU358 4.2 43.4 1.0 C C:GLU357 4.3 45.1 1.0 CD2 A:HIS139 4.5 43.9 1.0 CA A:ARG140 4.6 42.2 1.0 CA C:LEU358 4.6 43.7 1.0 O C:GLU357 4.7 48.0 1.0 CB C:LEU358 4.7 43.5 1.0 CA C:GLU357 4.7 45.7 1.0 O A:HIS139 4.8 41.0 1.0 O A:ARG140 4.9 42.8 1.0 CB C:GLN313 4.9 42.5 1.0

Chlorine binding site 10 out of 12 in the G6 in Complex with CRM1-Ran-RANBP1


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 10 of G6 in Complex with CRM1-Ran-RANBP1 within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl1112 b:93.3 occ:1.00 O C:HOH1516 3.1 61.3 1.0 OG1 C:THR705 3.4 48.5 1.0 O C:ASN701 3.9 49.2 1.0 C C:ASN701 4.0 48.0 1.0 N C:ILE702 4.1 47.0 1.0 CA C:ILE702 4.1 48.1 1.0 CG1 C:ILE702 4.3 48.8 1.0 O C:HOH1649 4.3 60.4 1.0 CB C:THR705 4.4 49.5 1.0 CB C:ASN701 4.4 51.0 1.0 CB C:PRO672 4.7 49.3 1.0 CA C:ASN701 4.8 49.8 1.0 CB C:ILE702 4.8 48.9 1.0 CG2 C:THR705 4.9 48.7 1.0 CA C:PRO672 4.9 49.9 1.0

Q.Sun, Y.Lei. F1 in Complex with CRM1-Ran-RANBP1 To Be Published.