Chlorine in PDB 8hug: F1 in Complex with CRM1-Ran-RANBP1

The structure of F1 in Complex with CRM1-Ran-RANBP1, PDB code: 8hug was solved by Q.Sun, Y.Lei, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.84 / 2.15
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	105.57, 105.57, 304, 90, 90, 90
R / Rfree (%)	18.7 / 22.4

The structure of F1 in Complex with CRM1-Ran-RANBP1 also contains other interesting chemical elements:

Fluorine	(F)	1 atom
Magnesium	(Mg)	1 atom

The binding sites of Chlorine atom in the F1 in Complex with CRM1-Ran-RANBP1 (pdb code 8hug). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the F1 in Complex with CRM1-Ran-RANBP1, PDB code: 8hug:
Jump to Chlorine binding site number: 1; 2; 3; 4;

Chlorine binding site 1 out of 4 in the F1 in Complex with CRM1-Ran-RANBP1


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of F1 in Complex with CRM1-Ran-RANBP1 within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl1101 b:85.1 occ:1.00 O C:ARG325 3.5 45.4 1.0 N C:ALA328 3.6 50.5 1.0 N C:ARG327 3.7 47.1 1.0 C C:ARG325 3.8 47.3 1.0 O C:ALA324 3.9 50.6 1.0 CB C:ALA328 4.0 51.5 1.0 CG C:ARG327 4.0 48.3 1.0 N C:ASN326 4.1 44.6 1.0 O C:HOH1610 4.1 65.9 1.0 C C:ASN326 4.3 46.2 1.0 O C:LEU323 4.3 48.0 1.0 CA C:ALA328 4.4 53.1 1.0 CA C:ASN326 4.5 45.8 1.0 C C:ARG327 4.5 49.8 1.0 CA C:ARG327 4.5 50.0 1.0 C C:ALA324 4.5 47.1 1.0 CA C:ARG325 4.6 48.1 1.0 O C:HOH1479 4.6 81.3 1.0 O C:HOH1480 4.7 66.4 1.0 NE C:ARG327 4.7 48.3 1.0 CB C:ARG327 4.8 49.7 1.0 N C:ARG325 4.9 47.2 1.0 CZ C:ARG327 5.0 48.9 1.0

Chlorine binding site 2 out of 4 in the F1 in Complex with CRM1-Ran-RANBP1


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of F1 in Complex with CRM1-Ran-RANBP1 within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl1102 b:90.2 occ:1.00 NH1 C:ARG77 3.5 86.2 1.0 O C:LYS1040 3.9 56.8 1.0 C C:LYS1040 4.1 55.7 1.0 NE2 C:HIS1005 4.3 51.5 1.0 N C:GLU1041 4.3 54.9 1.0 CD2 C:HIS1005 4.3 51.2 1.0 CA C:GLU1041 4.4 57.5 1.0 O C:ILE1039 4.4 53.6 1.0 CG2 C:VAL1042 4.5 57.5 1.0 C C:GLU1041 4.5 55.1 1.0 CE1 C:HIS1005 4.5 50.9 1.0 CZ C:ARG77 4.5 84.1 1.0 O C:ARG77 4.6 59.4 1.0 CG C:HIS1005 4.7 51.0 1.0 O C:GLU1041 4.7 52.9 1.0 ND1 C:HIS1005 4.7 51.7 1.0 CB C:ARG77 4.8 66.0 1.0 CA C:LYS1040 4.9 55.9 1.0 N C:VAL1042 4.9 53.0 1.0 CE C:LYS78 4.9 74.4 1.0 O C:HOH1611 5.0 81.5 1.0

Chlorine binding site 3 out of 4 in the F1 in Complex with CRM1-Ran-RANBP1


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of F1 in Complex with CRM1-Ran-RANBP1 within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl1108 b:30.0 occ:1.00 O C:HOH1459 3.6 62.8 1.0 NE2 C:HIS609 3.7 61.4 1.0 CD C:LYS567 3.8 64.7 1.0 CE C:LYS567 3.9 66.5 1.0 CD2 C:HIS609 4.0 62.5 1.0 NZ C:LYS567 4.2 71.8 1.0 CB C:TYR608 4.3 65.8 1.0 CG C:LYS567 4.4 62.1 1.0 CD1 C:TYR608 4.5 74.1 1.0 CG C:TYR608 4.6 70.4 1.0 CE1 C:HIS609 4.9 65.3 1.0

Chlorine binding site 4 out of 4 in the F1 in Complex with CRM1-Ran-RANBP1


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of F1 in Complex with CRM1-Ran-RANBP1 within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl1110 b:109.6 occ:1.00 CL7 C:N591110 0.0 109.6 1.0 C05 C:N591110 1.8 103.6 1.0 C06 C:N591110 2.7 102.2 1.0 C04 C:N591110 2.8 103.8 1.0 CG C:MET556 3.8 60.8 1.0 CG2 C:ILE555 3.9 60.0 1.0 C01 C:N591110 4.0 105.5 1.0 CA C:MET556 4.1 57.2 1.0 N C:MET556 4.1 56.2 1.0 C03 C:N591110 4.1 103.4 1.0 CD2 C:LEU580 4.5 57.0 1.0 C C:ILE555 4.5 57.4 1.0 CB C:MET556 4.5 58.6 1.0 CE2 C:PHE583 4.5 72.3 1.0 C02 C:N591110 4.6 104.2 1.0 CB C:LYS579 4.7 71.0 1.0 CG1 C:VAL576 4.7 57.4 1.0 CB C:ILE555 4.7 58.2 1.0 O C:ILE555 4.7 56.3 1.0 CG C:LYS579 4.7 76.3 1.0 CG2 C:VAL559 4.8 60.1 1.0 O C:VAL576 4.9 54.5 1.0

Q.Sun, Y.Lei. F1 in Complex with CRM1-Ran-RANBP1 To Be Published.