Chlorine in PDB 8i7w: Cryo-Em Structure of GSK256073 Bound Human Hydroxy-Carboxylic Acid Receptor 2 in Complex with Gi Heterotrimer

The binding sites of Chlorine atom in the Cryo-Em Structure of GSK256073 Bound Human Hydroxy-Carboxylic Acid Receptor 2 in Complex with Gi Heterotrimer (pdb code 8i7w). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Cryo-Em Structure of GSK256073 Bound Human Hydroxy-Carboxylic Acid Receptor 2 in Complex with Gi Heterotrimer, PDB code: 8i7w:

Chlorine binding site 1 out of 1 in the Cryo-Em Structure of GSK256073 Bound Human Hydroxy-Carboxylic Acid Receptor 2 in Complex with Gi Heterotrimer


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Cryo-Em Structure of GSK256073 Bound Human Hydroxy-Carboxylic Acid Receptor 2 in Complex with Gi Heterotrimer within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl401 b:87.6 occ:1.00 CL17 A:OKL401 0.0 87.6 1.0 C15 A:OKL401 1.8 87.1 1.0 N14 A:OKL401 2.8 84.2 1.0 N16 A:OKL401 2.8 80.7 1.0 OH A:TYR284 2.9 75.0 1.0 OH A:TYR87 3.3 106.6 1.0 CE2 A:TYR284 3.3 79.5 1.0 CD2 A:LEU83 3.5 102.6 1.0 CZ A:TYR284 3.5 74.7 1.0 C13 A:OKL401 3.9 77.7 1.0 C12 A:OKL401 3.9 77.0 1.0 CB A:LEU280 4.0 84.1 1.0 CZ A:TYR87 4.1 106.0 1.0 CD1 A:LEU280 4.2 83.0 1.0 N A:SER281 4.4 82.9 1.0 CE1 A:TYR87 4.4 107.1 1.0 C A:LEU280 4.5 86.4 1.0 CD2 A:TYR284 4.6 77.3 1.0 CG A:LEU280 4.6 82.2 1.0 CA A:SER281 4.7 84.3 1.0 O A:LEU280 4.8 89.9 1.0 CE1 A:TYR284 4.9 71.2 1.0 CA A:LEU280 4.9 85.6 1.0 O A:PHE277 4.9 98.5 1.0 CD2 A:LEU280 5.0 83.0 1.0

J.H.Park, K.Kawakami, N.Ishimoto, T.Ikuta, M.Ohki, T.Ekimoto, M.Ikeguchi, D.S.Lee, Y.H.Lee, J.R.H.Tame, A.Inoue, S.Y.Park. Structural Basis For Ligand Recognition and Signaling of Hydroxy-Carboxylic Acid Receptor 2. Nat Commun V. 14 7150 2023.
ISSN: ESSN 2041-1723
PubMed: 37932263
DOI: 10.1038/S41467-023-42764-8