Chlorine in PDB 8i91: ACE2-SIT1 Complex Bound with Proline

All present enzymatic activity of ACE2-SIT1 Complex Bound with Proline:
3.4.17.23;

The structure of ACE2-SIT1 Complex Bound with Proline also contains other interesting chemical elements:

Zinc

(Zn)

2 atoms

The binding sites of Chlorine atom in the ACE2-SIT1 Complex Bound with Proline (pdb code 8i91). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the ACE2-SIT1 Complex Bound with Proline, PDB code: 8i91:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the ACE2-SIT1 Complex Bound with Proline


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of ACE2-SIT1 Complex Bound with Proline within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl702 b:30.0 occ:1.00 OH B:TYR47 2.2 66.7 1.0 NE2 B:GLN247 2.8 71.7 1.0 OG B:SER287 3.2 57.0 1.0 OG B:SER251 3.2 68.4 1.0 CZ B:TYR47 3.3 66.7 1.0 CB B:SER251 3.4 68.4 1.0 ND2 B:ASN27 3.5 68.5 1.0 CE1 B:TYR47 3.8 66.7 1.0 ND2 B:ASN283 3.9 54.7 1.0 CD B:GLN247 3.9 71.7 1.0 CB B:SER287 4.1 57.0 1.0 O B:GLY26 4.3 69.3 1.0 CG B:GLN247 4.3 71.7 1.0 CE2 B:TYR47 4.4 66.7 1.0 OD1 B:ASN283 4.6 54.7 1.0 CG B:ASN283 4.7 54.7 1.0 CG B:ASN27 4.7 68.5 1.0 O B:GLN247 4.8 71.7 1.0 CA B:SER251 4.9 68.4 1.0 OE1 B:GLN247 4.9 71.7 1.0 C B:GLY26 5.0 69.3 1.0

Chlorine binding site 2 out of 2 in the ACE2-SIT1 Complex Bound with Proline


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of ACE2-SIT1 Complex Bound with Proline within 5.0Å range: probe atom residue distance (Å) B Occ D:Cl702 b:30.0 occ:1.00 OH D:TYR47 2.2 66.7 1.0 NE2 D:GLN247 2.8 71.7 1.0 OG D:SER287 3.2 57.0 1.0 OG D:SER251 3.2 68.4 1.0 CZ D:TYR47 3.3 66.7 1.0 CB D:SER251 3.4 68.4 1.0 ND2 D:ASN27 3.5 68.5 1.0 CE1 D:TYR47 3.8 66.7 1.0 ND2 D:ASN283 3.9 54.7 1.0 CD D:GLN247 3.9 71.7 1.0 CB D:SER287 4.1 57.0 1.0 O D:GLY26 4.3 69.3 1.0 CG D:GLN247 4.3 71.7 1.0 CE2 D:TYR47 4.4 66.7 1.0 OD1 D:ASN283 4.6 54.7 1.0 CG D:ASN283 4.7 54.7 1.0 CG D:ASN27 4.7 68.5 1.0 O D:GLN247 4.8 71.7 1.0 CA D:SER251 4.9 68.4 1.0 OE1 D:GLN247 4.9 71.7 1.0 C D:GLY26 5.0 69.3 1.0

Y.Li, Y.Chen, Y.Zhang, Y.Shen, K.Xu, Y.Liu, Z.Wang, R.Yan. Structural Insight Into the Substrate Recognition and Transport Mechanism of Amino Acid Transporter Complex ACE2-B 0 AT1 and ACE2-SIT1. Cell Discov V. 9 93 2023.
ISSN: ESSN 2056-5968
PubMed: 37684251
DOI: 10.1038/S41421-023-00596-2