Chlorine in PDB 8ia5: Small Peptide Enhances the Binding of Nutline-3A to N-Terminal Domain of Mdmx

The structure of Small Peptide Enhances the Binding of Nutline-3A to N-Terminal Domain of Mdmx, PDB code: 8ia5 was solved by X.Y.Cheng, Q.Y.Wei, Y.Huang, Z.D.Su, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	26.81 / 1.93
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	47.08, 47.08, 90.45, 90, 90, 90
R / Rfree (%)	21 / 28.4

The binding sites of Chlorine atom in the Small Peptide Enhances the Binding of Nutline-3A to N-Terminal Domain of Mdmx (pdb code 8ia5). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Small Peptide Enhances the Binding of Nutline-3A to N-Terminal Domain of Mdmx, PDB code: 8ia5:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Small Peptide Enhances the Binding of Nutline-3A to N-Terminal Domain of Mdmx


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Small Peptide Enhances the Binding of Nutline-3A to N-Terminal Domain of Mdmx within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl201 b:42.8 occ:1.00 CL1 A:NUT201 0.0 42.8 1.0 C22 A:NUT201 1.7 39.8 1.0 C23 A:NUT201 2.7 44.5 1.0 C21 A:NUT201 2.7 41.6 1.0 H24 A:NUT201 2.8 43.6 1.0 H25 A:NUT201 2.8 42.1 1.0 HD23 A:LEU97 2.9 52.5 1.0 HD13 A:ILE59 2.9 35.9 1.0 HB3 A:LEU55 3.0 37.1 1.0 HZ A:PHE89 3.0 47.7 1.0 HD22 A:LEU97 3.1 52.5 1.0 HD12 A:ILE59 3.2 35.9 1.0 HD11 A:LEU97 3.2 51.1 1.0 CD2 A:LEU97 3.5 52.8 1.0 CD1 A:ILE59 3.5 35.5 1.0 HD12 A:LEU97 3.6 51.2 1.0 HD12 A:LEU55 3.7 41.8 1.0 CD1 A:LEU97 3.8 50.8 1.0 CZ A:PHE89 3.8 48.7 1.0 HD11 A:ILE59 3.9 35.9 1.0 CB A:LEU55 3.9 37.3 1.0 C24 A:NUT201 4.0 45.6 1.0 C20 A:NUT201 4.0 45.4 1.0 HB2 A:LEU55 4.0 37.1 1.0 HD23 A:LEU80 4.2 41.3 1.0 HD22 A:LEU55 4.2 41.1 1.0 HD21 A:LEU97 4.2 52.5 1.0 CG A:LEU97 4.3 52.3 1.0 HE1 A:PHE89 4.4 48.8 1.0 CD1 A:LEU55 4.4 42.7 1.0 C A:LEU55 4.5 33.6 1.0 HE3 A:MET52 4.5 46.5 1.0 C19 A:NUT201 4.5 43.5 1.0 HD13 A:LEU55 4.5 41.7 1.0 CE1 A:PHE89 4.5 46.8 1.0 HE2 A:MET52 4.6 46.4 1.0 O A:LEU55 4.6 38.9 1.0 HE2 A:PHE89 4.6 47.3 1.0 HA2 A:GLY56 4.6 36.5 1.0 CG A:LEU55 4.6 39.6 1.0 HD13 A:LEU97 4.7 51.0 1.0 CE2 A:PHE89 4.7 46.3 1.0 H26 A:NUT201 4.7 44.1 1.0 H23 A:NUT201 4.7 44.8 1.0 N A:GLY56 4.7 35.0 1.0 HD11 A:LEU80 4.7 34.9 1.0 HG13 A:ILE59 4.7 36.6 1.0 CG1 A:ILE59 4.8 36.5 1.0 CA A:LEU55 4.8 34.2 1.0 H A:GLY56 4.9 35.0 1.0 CD2 A:LEU55 4.9 41.8 1.0 HG A:LEU97 4.9 50.2 1.0 HB2 A:LEU97 5.0 44.2 1.0

Chlorine binding site 2 out of 2 in the Small Peptide Enhances the Binding of Nutline-3A to N-Terminal Domain of Mdmx


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Small Peptide Enhances the Binding of Nutline-3A to N-Terminal Domain of Mdmx within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl201 b:48.7 occ:1.00 CL A:NUT201 0.0 48.7 1.0 C15 A:NUT201 1.7 51.3 1.0 C16 A:NUT201 2.7 47.8 1.0 C14 A:NUT201 2.7 52.4 1.0 HB2 B:LEU2 2.7 50.1 1.0 H31 A:NUT201 2.8 47.3 1.0 HD21 A:LEU97 2.8 52.5 1.0 H32 A:NUT201 2.8 51.4 1.0 HB2 A:PRO94 3.0 57.7 1.0 HG3 B:GLU3 3.1 63.9 1.0 HE2 A:TYR98 3.2 48.2 1.0 HD13 B:LEU2 3.4 50.5 1.0 HE1 A:MET52 3.4 46.4 1.0 HG3 A:PRO94 3.5 58.2 1.0 CB B:LEU2 3.6 49.1 1.0 HB3 B:LEU2 3.6 50.1 1.0 CB A:PRO94 3.6 58.7 1.0 HB3 A:PRO94 3.7 57.8 1.0 CE2 A:TYR98 3.7 49.9 1.0 CD2 A:LEU97 3.7 52.8 1.0 OE1 B:GLU3 3.9 75.1 1.0 CG B:GLU3 3.9 64.6 1.0 CG A:PRO94 3.9 58.6 1.0 CD B:GLU3 3.9 74.4 1.0 HG2 A:PRO94 3.9 58.0 1.0 H B:GLU3 3.9 48.2 1.0 HE3 A:MET52 3.9 46.5 1.0 C17 A:NUT201 4.0 42.4 1.0 C13 A:NUT201 4.0 49.7 1.0 HD23 A:LEU97 4.0 52.5 1.0 HB3 A:LEU97 4.0 44.2 1.0 HG A:LEU97 4.1 50.2 1.0 N B:GLU3 4.1 47.1 1.0 CE A:MET52 4.1 45.7 1.0 CD1 B:LEU2 4.2 50.1 1.0 C B:LEU2 4.3 49.3 1.0 HA B:GLU3 4.3 49.5 1.0 CZ A:TYR98 4.3 46.5 1.0 HD22 A:LEU97 4.3 52.5 1.0 CD2 A:TYR98 4.3 45.5 1.0 OH A:TYR98 4.4 56.7 1.0 HD2 A:TYR98 4.4 46.8 1.0 CG A:LEU97 4.4 52.3 1.0 CG B:LEU2 4.4 51.3 1.0 HG2 B:GLU3 4.4 64.1 1.0 HD12 B:LEU2 4.5 50.5 1.0 C12 A:NUT201 4.5 45.4 1.0 CA B:LEU2 4.5 51.2 1.0 OE2 B:GLU3 4.5 70.4 1.0 HE2 A:MET52 4.6 46.4 1.0 CA B:GLU3 4.6 48.2 1.0 HG B:LEU2 4.6 49.9 1.0 H30 A:NUT201 4.7 44.5 1.0 H33 A:NUT201 4.7 49.2 1.0 CB A:LEU97 4.7 42.6 1.0 H B:LEU2 4.8 56.1 1.0 O B:LEU2 4.8 51.6 1.0 CB B:GLU3 4.9 54.2 1.0 HD11 B:LEU2 5.0 50.5 1.0

X.Y.Cheng, Q.Y.Wei, Y.Huang, Z.D.Su. Small Peptide Enhances the Binding of Nutline-3A to N-Terminal Domain of Mdmx To Be Published.