Chlorine in PDB 8ihb: Cryo-Em Structure of HCA2-Gi Complex with GSK256073

The binding sites of Chlorine atom in the Cryo-Em Structure of HCA2-Gi Complex with GSK256073 (pdb code 8ihb). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Cryo-Em Structure of HCA2-Gi Complex with GSK256073, PDB code: 8ihb:

Chlorine binding site 1 out of 1 in the Cryo-Em Structure of HCA2-Gi Complex with GSK256073


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Cryo-Em Structure of HCA2-Gi Complex with GSK256073 within 5.0Å range: probe atom residue distance (Å) B Occ R:Cl602 b:83.3 occ:1.00 CL17 R:OKL602 0.0 83.3 1.0 C15 R:OKL602 1.7 81.4 1.0 N14 R:OKL602 2.7 83.0 1.0 N16 R:OKL602 2.7 77.1 1.0 OH R:TYR87 3.3 91.2 1.0 C13 R:OKL602 3.8 75.5 1.0 CE2 R:TYR87 3.8 89.7 1.0 CE2 R:TYR284 3.8 71.7 1.0 C12 R:OKL602 3.8 73.8 1.0 CZ R:TYR87 4.0 91.4 1.0 OH R:TYR284 4.2 75.5 1.0 CG R:LEU280 4.2 66.5 1.0 N R:SER281 4.3 70.2 1.0 C R:LEU280 4.4 68.4 1.0 O R:LEU280 4.4 73.2 1.0 CA R:SER281 4.4 73.9 1.0 CB R:LEU280 4.4 66.9 1.0 CD2 R:LEU280 4.4 70.5 1.0 CZ R:TYR284 4.4 70.1 1.0 O R:PHE277 4.5 81.4 1.0 CD2 R:LEU83 4.6 91.6 1.0 CD1 R:LEU34 4.6 85.8 1.0 CD2 R:LEU34 4.6 86.1 1.0 CB R:SER281 4.6 75.0 1.0 CD2 R:TYR284 4.7 70.3 1.0 CD1 R:LEU83 4.8 88.5 1.0

S.Suzuki, K.Tanaka, K.Nishikawa, H.Suzuki, A.Oshima, Y.Fujiyoshi. Structural Basis of Signaling Mechanisms of Hydroxycarboxylic Acid Receptors Through Ligand Binding To Be Published.