Chlorine in PDB 8iyx: Cryo-Em Structure of the GPR34 Receptor in Complex with the Antagonist Yl-365

The binding sites of Chlorine atom in the Cryo-Em Structure of the GPR34 Receptor in Complex with the Antagonist Yl-365 (pdb code 8iyx). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Cryo-Em Structure of the GPR34 Receptor in Complex with the Antagonist Yl-365, PDB code: 8iyx:

Chlorine binding site 1 out of 1 in the Cryo-Em Structure of the GPR34 Receptor in Complex with the Antagonist Yl-365


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Cryo-Em Structure of the GPR34 Receptor in Complex with the Antagonist Yl-365 within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl401 b:82.8 occ:1.00 CL36 C:S6R401 0.0 82.8 1.0 C35 C:S6R401 1.8 82.8 1.0 C37 C:S6R401 2.7 82.8 1.0 C34 C:S6R401 2.8 82.8 1.0 C31 C:S6R401 4.0 82.8 1.0 C33 C:S6R401 4.1 82.8 1.0 CA C:GLY131 4.4 65.8 1.0 C32 C:S6R401 4.6 82.8 1.0 CE2 C:TYR135 4.6 62.4 1.0 C C:GLY131 4.6 65.8 1.0 N C:THR132 4.9 62.3 1.0 CD2 C:TYR135 4.9 62.4 1.0 NH2 C:ARG208 5.0 124.9 1.0

A.Xia, X.Yong, C.Zhang, G.Lin, G.Jia, C.Zhao, X.Wang, Y.Hao, Y.Wang, P.Zhou, X.Yang, Y.Deng, C.Wu, Y.Chen, J.Zhu, X.Tang, J.Liu, S.Zhang, J.Zhang, Z.Xu, Q.Hu, J.Zhao, Y.Yue, W.Yan, Z.Su, Y.Wei, R.Zhou, H.Dong, Z.Shao, S.Yang. Cryo-Em Structures of Human GPR34 Enable the Identification of Selective Antagonists. Proc.Natl.Acad.Sci.Usa V. 120 35120 2023.
ISSN: ESSN 1091-6490
PubMed: 37733739
DOI: 10.1073/PNAS.2308435120