Chlorine in PDB 8j22: Cryo-Em Structure of FFAR2 Complex Bound with Tug-1375

The binding sites of Chlorine atom in the Cryo-Em Structure of FFAR2 Complex Bound with Tug-1375 (pdb code 8j22). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Cryo-Em Structure of FFAR2 Complex Bound with Tug-1375, PDB code: 8j22:

Chlorine binding site 1 out of 1 in the Cryo-Em Structure of FFAR2 Complex Bound with Tug-1375


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Cryo-Em Structure of FFAR2 Complex Bound with Tug-1375 within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl401 b:89.9 occ:1.00 CL01 C:9UJ401 0.0 89.9 1.0 C16 C:9UJ401 1.7 74.3 1.0 C21 C:9UJ401 2.6 74.6 1.0 C12 C:9UJ401 2.7 70.6 1.0 O05 C:9UJ401 2.9 78.2 1.0 N07 C:9UJ401 3.0 70.8 1.0 C13 C:9UJ401 3.2 72.4 1.0 C18 C:9UJ401 3.2 70.9 1.0 C10 C:9UJ401 3.3 73.8 1.0 CG2 C:THR163 3.4 98.0 1.0 C14 C:9UJ401 3.5 77.5 1.0 C15 C:9UJ401 3.6 72.9 1.0 O04 C:9UJ401 3.7 76.2 1.0 C09 C:9UJ401 3.8 76.1 1.0 C26 C:9UJ401 3.9 71.5 1.0 C17 C:9UJ401 4.0 69.8 1.0 OG1 C:THR163 4.2 100.0 1.0 CB C:THR163 4.3 101.8 1.0 O03 C:9UJ401 4.3 79.0 1.0 C23 C:9UJ401 4.4 72.1 1.0 C22 C:9UJ401 4.4 68.4 1.0 OE2 C:GLU166 4.5 96.8 1.0 C11 C:9UJ401 4.6 77.0 1.0 CG C:GLU166 4.8 96.6 1.0 S02 C:9UJ401 4.9 88.6 1.0 CZ C:PHE168 4.9 79.7 1.0 C19 C:9UJ401 5.0 77.6 1.0

F.Li, L.Tai, X.Sun, Z.Lv, W.Tang, T.Wang, Z.Zhao, D.Gong, S.Ma, S.Tang, Q.Gu, X.Zhu, M.Yu, X.Liu, J.Wang. Molecular Recognition and Activation Mechanism of Short-Chain Fatty Acid Receptors FFAR2/3. Cell Res. 2024.
ISSN: ISSN 1001-0602
PubMed: 38191689
DOI: 10.1038/S41422-023-00914-Z