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Chlorine in PDB 8kh9: Crystal Structure of FGFR4(V550M) Kinase Domain with 8ZProtein crystallography data
The structure of Crystal Structure of FGFR4(V550M) Kinase Domain with 8Z, PDB code: 8kh9
was solved by
Q.M.Lin,
X.J.Chen,
Y.H.Chen,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of FGFR4(V550M) Kinase Domain with 8Z
(pdb code 8kh9). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of FGFR4(V550M) Kinase Domain with 8Z, PDB code: 8kh9: Jump to Chlorine binding site number: 1; 2; Chlorine binding site 1 out of 2 in 8kh9Go back to Chlorine Binding Sites List in 8kh9
Chlorine binding site 1 out
of 2 in the Crystal Structure of FGFR4(V550M) Kinase Domain with 8Z
Mono view Stereo pair view
Chlorine binding site 2 out of 2 in 8kh9Go back to Chlorine Binding Sites List in 8kh9
Chlorine binding site 2 out
of 2 in the Crystal Structure of FGFR4(V550M) Kinase Domain with 8Z
Mono view Stereo pair view
Reference:
F.Yang,
Q.Lin,
X.Song,
H.Huang,
X.Chen,
J.Tan,
Y.Li,
Y.Zhou,
Z.Tu,
H.Du,
Z.M.Zhang,
R.Ortega,
X.Lin,
A.V.Patterson,
J.B.Smaill,
Y.Chen,
X.Lu.
Discovery of 6-Formylpyridyl Urea Derivatives As Potent Reversible-Covalent Fibroblast Growth Factor Receptor 4 Inhibitors with Improved Anti-Hepatocellular Carcinoma Activity. J.Med.Chem. V. 67 2667 2024.
Page generated: Sun Aug 11 10:51:00 2024
ISSN: ISSN 0022-2623 PubMed: 38348819 DOI: 10.1021/ACS.JMEDCHEM.3C01810 |
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