Chlorine in PDB 8pm6: Human Bile Salt Export Pump (Bsep) in Complex with Inhibitor Gbm in Nanodiscs

The binding sites of Chlorine atom in the Human Bile Salt Export Pump (Bsep) in Complex with Inhibitor Gbm in Nanodiscs (pdb code 8pm6). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Human Bile Salt Export Pump (Bsep) in Complex with Inhibitor Gbm in Nanodiscs, PDB code: 8pm6:

Chlorine binding site 1 out of 1 in the Human Bile Salt Export Pump (Bsep) in Complex with Inhibitor Gbm in Nanodiscs


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Human Bile Salt Export Pump (Bsep) in Complex with Inhibitor Gbm in Nanodiscs within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1409 b:119.5 occ:1.00 CL1 A:GBM1409 0.0 119.5 1.0 C31 A:GBM1409 1.7 112.1 1.0 C32 A:GBM1409 2.7 110.2 1.0 C29 A:GBM1409 2.7 108.8 1.0 CD1 A:PHE776 3.3 70.2 1.0 CB A:PHE776 3.4 59.4 1.0 N A:SER777 3.4 43.7 1.0 OG A:SER1022 3.6 77.7 1.0 CG A:PHE776 3.6 67.4 1.0 O A:ALA773 3.7 72.2 1.0 C A:PHE776 3.7 56.8 1.0 CA A:SER777 3.9 56.1 1.0 C30 A:GBM1409 4.0 108.8 1.0 C27 A:GBM1409 4.0 107.3 1.0 CB A:SER777 4.1 64.4 1.0 CB A:SER1022 4.1 68.7 1.0 CA A:PHE776 4.2 50.0 1.0 CE1 A:PHE776 4.3 66.3 1.0 O A:PHE776 4.3 71.4 1.0 O A:PHE1018 4.3 84.8 1.0 CB A:PHE1018 4.4 59.0 1.0 C28 A:GBM1409 4.5 106.8 1.0 C A:PHE1018 4.5 75.1 1.0 C A:ALA773 4.6 58.1 1.0 CA A:ALA773 4.8 45.7 1.0 CD2 A:PHE776 4.8 68.8 1.0 N A:ARG1019 4.9 67.5 1.0 N A:PHE776 5.0 52.6 1.0

H.Liu, R.N.Irobalieva, J.Kowal, D.Ni, K.Nosol, R.Bang-Sorensen, L.Lancien, H.Stahlberg, B.Stieger, K.P.Locher. Structural Basis of Bile Salt Extrusion and Small-Molecule Inhibition in Human Bsep. Nat Commun V. 14 7296 2023.
ISSN: ESSN 2041-1723
PubMed: 37949847
DOI: 10.1038/S41467-023-43109-1