Chlorine in PDB 8q2v: Crystal Structure of YTHDC1 in Complex with Compound 7 (ZA_560)

The structure of Crystal Structure of YTHDC1 in Complex with Compound 7 (ZA_560), PDB code: 8q2v was solved by R.K.Bedi, F.Zalesak, A.Caflisch, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	40.75 / 1.71
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	40.02, 103.86, 42.21, 90, 105.1, 90
R / Rfree (%)	20.9 / 25.1

The binding sites of Chlorine atom in the Crystal Structure of YTHDC1 in Complex with Compound 7 (ZA_560) (pdb code 8q2v). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of YTHDC1 in Complex with Compound 7 (ZA_560), PDB code: 8q2v:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Crystal Structure of YTHDC1 in Complex with Compound 7 (ZA_560)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of YTHDC1 in Complex with Compound 7 (ZA_560) within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl601 b:59.8 occ:1.00 CL17 A:IUQ601 0.0 59.8 1.0 C16 A:IUQ601 1.8 35.1 1.0 ND2 A:ASN364 2.7 42.4 1.0 N15 A:IUQ601 2.7 41.7 1.0 N18 A:IUQ601 2.7 34.8 1.0 ND2 A:ASN367 3.1 33.6 1.0 N A:ASN363 3.4 32.0 1.0 CB A:ASN363 3.5 40.0 1.0 CG A:ASN364 3.5 39.4 1.0 CG A:PRO431 3.6 57.6 1.0 N A:ASN364 3.7 32.5 1.0 OG A:SER362 3.8 29.4 1.0 O A:VAL429 3.8 53.0 1.0 CA A:ASN363 3.8 35.6 1.0 CD A:PRO431 3.9 59.4 1.0 C14 A:IUQ601 4.0 39.9 1.0 C03 A:IUQ601 4.0 31.8 1.0 OD1 A:ASN364 4.1 37.4 1.0 C A:ASN363 4.1 34.1 1.0 CG A:ASN367 4.2 35.5 1.0 ND2 A:ASN363 4.2 46.9 1.0 CG A:ASN363 4.4 46.5 1.0 CB A:ASN364 4.4 34.6 1.0 C A:SER362 4.5 30.1 1.0 C04 A:IUQ601 4.5 36.2 1.0 CA A:ASN364 4.6 30.4 1.0 CB A:ASN367 4.7 29.7 1.0 CA A:SER362 4.8 26.3 1.0 N A:PRO431 4.8 62.2 1.0 CB A:SER362 4.8 32.7 1.0 O A:ASN364 4.8 29.3 1.0 CB A:PRO431 4.8 61.5 1.0

Chlorine binding site 2 out of 2 in the Crystal Structure of YTHDC1 in Complex with Compound 7 (ZA_560)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of YTHDC1 in Complex with Compound 7 (ZA_560) within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl601 b:51.7 occ:1.00 CL17 B:IUQ601 0.0 51.7 1.0 C16 B:IUQ601 1.8 33.2 1.0 N15 B:IUQ601 2.7 29.5 1.0 N18 B:IUQ601 2.7 27.8 1.0 ND2 B:ASN364 2.9 37.5 1.0 N B:ASN363 3.3 30.9 1.0 OG B:SER362 3.3 30.5 1.0 CG B:ASN364 3.3 34.9 1.0 ND2 B:ASN367 3.3 26.4 1.0 N B:ASN364 3.4 29.3 1.0 OD1 B:ASN364 3.6 33.6 1.0 CB B:ASN363 3.7 36.4 1.0 CA B:ASN363 3.8 29.5 1.0 C14 B:IUQ601 3.9 31.7 1.0 CG B:PRO431 4.0 42.9 1.0 C03 B:IUQ601 4.0 28.2 1.0 C B:ASN363 4.0 31.2 1.0 O B:VAL429 4.2 32.5 1.0 CB B:ASN364 4.2 30.9 1.0 C B:SER362 4.3 25.7 1.0 CG B:ASN367 4.3 26.3 1.0 CA B:ASN364 4.4 30.2 1.0 CD B:PRO431 4.4 42.5 1.0 CB B:SER362 4.4 29.4 1.0 C04 B:IUQ601 4.5 26.9 1.0 CA B:SER362 4.5 31.1 1.0 CB B:ASN367 4.5 22.6 1.0 ND2 B:ASN363 4.5 46.0 1.0 CG B:ASN363 4.6 38.4 1.0 O B:ASN364 4.7 29.8 1.0

R.K.Bedi, F.Zalesak, A.Caflisch. Crystal Structure of YTHDC1 in Complex with Compound 7 (ZA_560) To Be Published.