Chlorine in PDB 8q2x: Crystal Structure of YTHDC1 in Complex with Compound 10 (ZA_294)

The structure of Crystal Structure of YTHDC1 in Complex with Compound 10 (ZA_294), PDB code: 8q2x was solved by R.K.Bedi, F.Zalesak, A.Caflisch, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	38.21 / 1.60
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	39.71, 103.45, 42.12, 90, 105.81, 90
R / Rfree (%)	21.1 / 24.5

The binding sites of Chlorine atom in the Crystal Structure of YTHDC1 in Complex with Compound 10 (ZA_294) (pdb code 8q2x). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of YTHDC1 in Complex with Compound 10 (ZA_294), PDB code: 8q2x:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Crystal Structure of YTHDC1 in Complex with Compound 10 (ZA_294)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of YTHDC1 in Complex with Compound 10 (ZA_294) within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl601 b:52.8 occ:1.00 CL01 A:IV6601 0.0 52.8 1.0 C02 A:IV6601 1.8 40.6 1.0 N21 A:IV6601 2.8 36.2 1.0 N03 A:IV6601 2.8 35.4 1.0 ND2 A:ASN367 2.8 34.2 1.0 ND2 A:ASN364 2.9 45.2 1.0 CG A:ASN364 3.3 40.4 1.0 OD1 A:ASN364 3.5 37.8 1.0 N A:ASN364 3.5 33.1 1.0 N A:ASN363 3.5 32.6 1.0 CB A:ASN363 3.6 43.7 1.0 OG A:SER362 3.6 35.0 1.0 O A:VAL429 3.8 49.3 1.0 CD A:PRO431 3.9 50.6 1.0 CG A:ASN367 3.9 37.4 1.0 CA A:ASN363 3.9 37.3 1.0 C A:ASN363 4.1 38.3 1.0 C04 A:IV6601 4.1 33.7 1.0 C08 A:IV6601 4.1 38.8 1.0 CG A:PRO431 4.2 54.4 1.0 CB A:ASN364 4.3 37.6 1.0 CB A:ASN367 4.4 34.0 1.0 CA A:ASN364 4.4 35.1 1.0 C A:SER362 4.5 35.3 1.0 O A:ASN364 4.6 32.6 1.0 C07 A:IV6601 4.7 37.0 1.0 O A:HOH717 4.7 43.9 1.0 CB A:PRO431 4.7 55.6 1.0 OD1 A:ASN367 4.8 35.8 1.0 CB A:SER362 4.8 35.6 1.0 CA A:SER362 4.8 29.6 1.0 N A:PRO431 4.8 53.5 1.0 CG A:ASN363 4.8 52.2 1.0 ND2 A:ASN363 4.9 55.1 1.0 C A:ASN364 5.0 33.7 1.0 C A:VAL429 5.0 48.0 1.0

Chlorine binding site 2 out of 2 in the Crystal Structure of YTHDC1 in Complex with Compound 10 (ZA_294)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of YTHDC1 in Complex with Compound 10 (ZA_294) within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl601 b:55.0 occ:1.00 CL01 B:IV6601 0.0 55.0 1.0 C02 B:IV6601 1.8 47.7 1.0 N21 B:IV6601 2.8 47.7 1.0 N03 B:IV6601 2.8 42.9 1.0 OD1 B:ASN364 2.8 48.2 1.0 CG B:ASN364 3.3 40.5 1.0 ND2 B:ASN367 3.3 32.7 1.0 N B:ASN363 3.3 41.4 1.0 N B:ASN364 3.4 35.3 1.0 OG B:SER362 3.5 36.0 1.0 ND2 B:ASN364 3.5 38.1 1.0 CG B:PRO431 3.8 58.1 1.0 CB B:ASN363 3.8 51.7 1.0 CA B:ASN363 3.9 44.0 1.0 C B:ASN363 4.0 41.3 1.0 CG B:ASN367 4.1 34.9 1.0 C04 B:IV6601 4.1 40.7 1.0 C08 B:IV6601 4.2 52.6 1.0 O B:VAL429 4.2 40.8 1.0 CB B:ASN364 4.3 41.0 1.0 CB B:ASN367 4.3 30.9 1.0 C B:SER362 4.3 35.8 1.0 CD B:PRO431 4.3 59.0 1.0 CA B:ASN364 4.4 40.0 1.0 O B:ASN364 4.5 39.7 1.0 CA B:SER362 4.6 34.0 1.0 CB B:SER362 4.6 33.0 1.0 C07 B:IV6601 4.7 48.1 1.0 O B:HOH767 4.9 54.3 1.0 C B:ASN364 4.9 35.1 1.0

R.K.Bedi, F.Zalesak, A.Caflisch. Crystal Structure of YTHDC1 in Complex with Compound 10 (ZA_294) To Be Published.