Chlorine in PDB 8qj3: Receptor Sd-AMT1 (Off-State)

The structure of Receptor Sd-AMT1 (Off-State), PDB code: 8qj3 was solved by S.L.Andrade, T.Pflueger, M.Gschell, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	48.97 / 1.90
Space group	H 3
Cell size a, b, c (Å), α, β, γ (°)	114.757, 114.757, 278.565, 90, 90, 120
R / Rfree (%)	16.2 / 18.4

The binding sites of Chlorine atom in the Receptor Sd-AMT1 (Off-State) (pdb code 8qj3). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Receptor Sd-AMT1 (Off-State), PDB code: 8qj3:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Receptor Sd-AMT1 (Off-State)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Receptor Sd-AMT1 (Off-State) within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl701 b:33.3 occ:1.00 O A:HOH830 2.7 22.5 1.0 N A:GLU112 2.9 14.6 1.0 ND2 A:ASN40 3.1 31.2 1.0 OH A:TYR119 3.4 33.4 1.0 CG2 A:VAL41 3.6 25.7 1.0 CA A:GLU112 3.6 15.9 1.0 CA A:ALA111 3.8 16.7 1.0 C A:ALA111 3.9 16.9 1.0 CG A:ASN40 3.9 29.8 1.0 CD2 A:LEU395 4.0 34.7 1.0 CB A:ASN40 4.0 27.6 1.0 CB A:ALA111 4.0 15.0 1.0 O A:HOH806 4.2 26.5 1.0 O A:ASN37 4.4 20.5 1.0 CB A:ASN37 4.4 17.0 1.0 C A:GLU112 4.5 16.8 1.0 CZ A:TYR119 4.6 36.9 1.0 N A:ARG113 4.7 17.1 1.0 CG A:GLU112 4.7 15.6 1.0 CB A:GLU112 4.7 15.9 1.0 OE2 A:GLU29 4.8 25.5 1.0 N A:VAL41 4.8 23.0 1.0 CG A:ASN37 4.8 20.7 1.0 CE2 A:TYR119 4.9 32.8 1.0 CB A:VAL41 5.0 28.8 1.0 OD1 A:ASN40 5.0 31.6 1.0 C A:ASN40 5.0 21.2 1.0 O A:HOH816 5.0 29.8 1.0

Chlorine binding site 2 out of 2 in the Receptor Sd-AMT1 (Off-State)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Receptor Sd-AMT1 (Off-State) within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl703 b:34.6 occ:1.00 O B:HOH820 2.8 22.0 1.0 ND2 B:ASN40 2.9 36.3 1.0 N B:GLU112 2.9 15.4 1.0 CG2 B:VAL41 3.2 18.8 1.0 OH B:TYR119 3.4 37.0 1.0 CA B:GLU112 3.6 17.0 1.0 CG B:ASN40 3.7 29.8 1.0 CD2 B:LEU395 3.8 41.7 1.0 CA B:ALA111 3.8 15.8 1.0 CB B:ASN40 3.9 29.1 1.0 C B:ALA111 3.9 16.6 1.0 CB B:ALA111 4.1 15.5 1.0 O B:HOH816 4.2 28.8 1.0 O B:ASN37 4.3 20.1 1.0 CB B:ASN37 4.4 18.6 1.0 C B:GLU112 4.5 17.5 1.0 CZ B:TYR119 4.6 36.3 1.0 CB B:VAL41 4.6 24.7 1.0 N B:VAL41 4.7 23.8 1.0 OE2 B:GLU29 4.7 22.7 1.0 CG B:GLU112 4.7 17.8 1.0 N B:ARG113 4.8 16.7 1.0 OD1 B:ASN40 4.8 31.1 1.0 CB B:GLU112 4.8 17.7 1.0 CA B:VAL41 4.8 23.4 1.0 CG B:ASN37 4.9 21.2 1.0 CG B:LEU395 4.9 32.2 1.0 CE2 B:TYR119 4.9 32.2 1.0 C B:ASN40 4.9 21.6 1.0 O B:HOH814 5.0 30.8 1.0 CB B:LEU395 5.0 29.0 1.0

T.Pfluger, M.Gschell, L.Zhang, V.Shnitsar, A.J.Zabadne, P.Zierep, S.Gunther, O.Einsle, S.L.A.Andrade. How Sensor Amt-Like Proteins Integrate Ammonium Signals. Sci Adv V. 10 M9441 2024.
ISSN: ESSN 2375-2548
PubMed: 38838143
DOI: 10.1126/SCIADV.ADM9441