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Atomistry » Chlorine » PDB 8q79-8qqe » 8qjt | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 8q79-8qqe » 8qjt » |
Chlorine in PDB 8qjt: Brm (SMARCA2) Bromodomain in Complex with Ligand 10Protein crystallography data
The structure of Brm (SMARCA2) Bromodomain in Complex with Ligand 10, PDB code: 8qjt
was solved by
P.S.Kerry,
A.J.Hole,
J.I.Perez-Dorado,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 8qjt:
The structure of Brm (SMARCA2) Bromodomain in Complex with Ligand 10 also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Brm (SMARCA2) Bromodomain in Complex with Ligand 10
(pdb code 8qjt). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Brm (SMARCA2) Bromodomain in Complex with Ligand 10, PDB code: 8qjt: Chlorine binding site 1 out of 1 in 8qjtGo back to Chlorine Binding Sites List in 8qjt
Chlorine binding site 1 out
of 1 in the Brm (SMARCA2) Bromodomain in Complex with Ligand 10
Mono view Stereo pair view
Reference:
M.Berlin,
J.Cantley,
M.Bookbinder,
E.Bortolon,
F.Broccatelli,
G.Cadelina,
E.W.Chan,
H.Chen,
X.Chen,
Y.Cheng,
T.K.Cheung,
K.Davenport,
D.Dinicola,
D.Gordon,
B.D.Hamman,
A.Harbin,
R.Haskell,
M.He,
A.J.Hole,
T.Januario,
P.S.Kerry,
S.G.Koenig,
L.Li,
M.Merchant,
I.Perez-Dorado,
J.Pizzano,
C.Quinn,
C.M.Rose,
E.Rousseau,
L.Soto,
L.R.Staben,
H.Sun,
Q.Tian,
J.Wang,
W.Wang,
C.S.Ye,
X.Ye,
P.Zhang,
Y.Zhou,
R.Yauch,
P.S.Dragovich.
Protacs Targeting Brm (SMARCA2) Afford Selective in Vivo Degradation Over BRG1 (SMARCA4) and Are Active in BRG1 Mutant Xenograft Tumor Models. J.Med.Chem. 2024.
Page generated: Tue Jul 30 12:00:05 2024
ISSN: ISSN 0022-2623 PubMed: 38180485 DOI: 10.1021/ACS.JMEDCHEM.3C01781 |
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