Chlorine in PDB 8rpr: Crystal Structure of Sgvm Methyltransferase in Complex with Alpha- Ketoleucine and ZN2+ Ion

The structure of Crystal Structure of Sgvm Methyltransferase in Complex with Alpha- Ketoleucine and ZN2+ Ion, PDB code: 8rpr was solved by R.Saleem-Batcha, Z.Zou, J.Breiltgens, M.Mueller, J.N.Andexer, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	47.40 / 2.14
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	67.031, 67.031, 182.745, 90, 90, 90
R / Rfree (%)	19.5 / 23.2

The structure of Crystal Structure of Sgvm Methyltransferase in Complex with Alpha- Ketoleucine and ZN2+ Ion also contains other interesting chemical elements:

Magnesium	(Mg)	5 atoms
Zinc	(Zn)	1 atom

The binding sites of Chlorine atom in the Crystal Structure of Sgvm Methyltransferase in Complex with Alpha- Ketoleucine and ZN2+ Ion (pdb code 8rpr). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Sgvm Methyltransferase in Complex with Alpha- Ketoleucine and ZN2+ Ion, PDB code: 8rpr:

Chlorine binding site 1 out of 1 in the Crystal Structure of Sgvm Methyltransferase in Complex with Alpha- Ketoleucine and ZN2+ Ion


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Sgvm Methyltransferase in Complex with Alpha- Ketoleucine and ZN2+ Ion within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl402 b:87.2 occ:1.00 NH2 A:ARG339 3.1 99.2 1.0 NH1 A:ARG262 3.6 82.1 1.0 NH2 A:ARG262 4.0 88.3 1.0 CZ A:ARG339 4.1 89.8 1.0 NH1 A:ARG339 4.2 86.7 1.0 CZ A:ARG262 4.3 84.7 1.0

C.Sommer-Kamann, J.Breiltgens, Z.Zou, S.Gerhardt, R.Saleem-Batcha, F.Kemper, O.Einsle, J.N.Andexer, M.Muller. Structures and Protein Engineering of the Alpha-Keto Acid C-Methyltransferases Sgvm and Mrsa For Rational Substrate Transfer. Chembiochem 00258 2024.
ISSN: ESSN 1439-7633
PubMed: 38887142
DOI: 10.1002/CBIC.202400258