Chlorine in PDB 8srx: Crystal Structure of Bak-Bax Heterodimer with Lysopc

The structure of Crystal Structure of Bak-Bax Heterodimer with Lysopc, PDB code: 8srx was solved by J.M.Brouwer, P.E.Czabotar, P.M.Colman, M.S.Miller, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	38.71 / 2.09
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	158.166, 45.562, 43.714, 90, 101.76, 90
R / Rfree (%)	21.6 / 26.5

The structure of Crystal Structure of Bak-Bax Heterodimer with Lysopc also contains other interesting chemical elements:

Sodium	(Na)	2 atoms
Zinc	(Zn)	1 atom

The binding sites of Chlorine atom in the Crystal Structure of Bak-Bax Heterodimer with Lysopc (pdb code 8srx). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Bak-Bax Heterodimer with Lysopc, PDB code: 8srx:

Chlorine binding site 1 out of 1 in the Crystal Structure of Bak-Bax Heterodimer with Lysopc


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Bak-Bax Heterodimer with Lysopc within 5.0Å range: probe atom residue distance (Å) B Occ D:Cl205 b:48.7 occ:1.00 O6 A:K6G201 2.8 37.2 1.0 C26 A:K6G201 3.2 62.3 1.0 C17 A:K6G201 3.5 35.0 1.0 CE D:LYS119 3.5 28.9 1.0 NZ D:LYS119 3.6 31.4 1.0 C19 A:K6G201 3.6 26.4 1.0 CD2 D:LEU122 3.7 27.4 1.0 CD D:LYS119 3.7 30.2 1.0 CD1 A:TYR143 3.8 42.2 1.0 CE1 A:TYR143 4.0 41.0 1.0 C21 A:K6G201 4.3 49.9 1.0 O3 A:K6G201 4.4 35.9 1.0 O2 A:K6G201 4.4 44.7 1.0 O A:HOH308 4.4 35.8 1.0 N1 A:K6G201 4.6 64.3 1.0 O D:HOH302 4.6 33.8 1.0 C22 A:K6G201 4.9 47.1 1.0 C16 A:K6G201 4.9 26.9 1.0 CG A:TYR143 4.9 34.2 1.0 CG D:LEU122 5.0 30.7 1.0

M.S.Miller, A.D.Cowan, J.M.Brouwer, S.T.Smyth, L.Peng, A.Z.Wardak, R.T.Uren, C.Luo, M.J.Roy, S.Shah, Z.Tan, G.E.Reid, P.M.Colman, P.E.Czabotar. Sequence Differences Between Bax and Bak Core Domains Manifest As Differences in Their Interactions with Lipids. Febs J. 2023.
ISSN: ISSN 1742-464X
PubMed: 38088212
DOI: 10.1111/FEBS.17031