Chlorine in PDB 8ste: Cryo-Em Structure of NKCC1 FU_CTD

The binding sites of Chlorine atom in the Cryo-Em Structure of NKCC1 FU_CTD (pdb code 8ste). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Cryo-Em Structure of NKCC1 FU_CTD, PDB code: 8ste:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Cryo-Em Structure of NKCC1 FU_CTD


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Cryo-Em Structure of NKCC1 FU_CTD within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1301 b:61.8 occ:1.00 CL1 A:FUN1301 0.0 61.8 1.0 C2 A:FUN1301 1.8 61.8 1.0 C1 A:FUN1301 2.7 61.8 1.0 C3 A:FUN1301 2.8 61.8 1.0 O A:MET794 2.9 46.7 1.0 O1 A:FUN1301 3.1 61.8 1.0 S1 A:FUN1301 3.2 61.8 1.0 N1 A:FUN1301 3.3 61.8 1.0 CB A:MET794 3.8 46.7 1.0 C A:MET794 4.0 46.7 1.0 CD2 A:LEU886 4.0 43.7 1.0 C11 A:FUN1301 4.0 61.8 1.0 C4 A:FUN1301 4.0 61.8 1.0 CD2 A:LEU863 4.2 54.4 1.0 CE1 A:TYR903 4.5 50.6 1.0 CA A:MET794 4.6 46.7 1.0 C10 A:FUN1301 4.6 61.8 1.0 O2 A:FUN1301 4.6 61.8 1.0 CD2 A:LEU906 4.7 48.3 1.0 CG A:LEU886 4.7 43.7 1.0 CD1 A:TYR903 4.8 50.6 1.0 CB A:LEU886 4.8 43.7 1.0 CE A:MET794 4.9 46.7 1.0 CD1 A:LEU863 4.9 54.4 1.0

Chlorine binding site 2 out of 2 in the Cryo-Em Structure of NKCC1 FU_CTD


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Cryo-Em Structure of NKCC1 FU_CTD within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl1301 b:62.7 occ:1.00 CL1 B:FUN1301 0.0 62.7 1.0 C2 B:FUN1301 1.8 62.7 1.0 C3 B:FUN1301 2.7 62.7 1.0 C1 B:FUN1301 2.8 62.7 1.0 O1 B:FUN1301 2.9 62.7 1.0 S1 B:FUN1301 3.2 62.7 1.0 CD2 B:LEU886 3.2 46.1 1.0 O B:MET794 3.4 51.3 1.0 CG B:MET794 3.4 51.3 1.0 N1 B:FUN1301 3.7 62.7 1.0 CD1 B:LEU906 3.7 51.5 1.0 CB B:MET794 3.8 51.3 1.0 CD2 B:LEU863 3.8 57.5 1.0 C11 B:FUN1301 4.0 62.7 1.0 C4 B:FUN1301 4.0 62.7 1.0 CD1 B:LEU863 4.1 57.5 1.0 C B:MET794 4.2 51.3 1.0 CG B:LEU863 4.5 57.5 1.0 C10 B:FUN1301 4.6 62.7 1.0 O2 B:FUN1301 4.6 62.7 1.0 CA B:MET794 4.6 51.3 1.0 CG B:LEU886 4.7 46.1 1.0 CD1 B:TYR903 5.0 52.6 1.0

M.A.Moseng, C.C.Su, K.Rios, M.Cui, M.Lyu, P.Glaza, P.A.Klenotic, E.Delpire, E.W.Yu. Inhibition Mechanism of NKCC1 Involves the Carboxyl Terminus and Long-Range Conformational Coupling. Sci Adv V. 8 Q0952 2022.
ISSN: ESSN 2375-2548
PubMed: 36306358
DOI: 10.1126/SCIADV.ABQ0952